Zobrazeno 1 - 10
of 41
pro vyhledávání: '"R. Al Mubarak"'
Autor:
Paul S. Baxter, Nóra M. Márkus, Owen Dando, Xin He, Bashayer R. Al-Mubarak, Jing Qiu, Giles E. Hardingham
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Abstract Many neurodegenerative diseases are associated with neuronal misfolded protein accumulation, indicating a need for proteostasis-promoting strategies. Here we show that de-repressing the transcription factor Nrf2, epigenetically shut-off in e
Externí odkaz:
https://doaj.org/article/31e7accf92224a198e1bdc3f8cf5ddba
Autor:
Bashayer R. Al-Mubarak, Karen F.S. Bell, Sudhir Chowdhry, Paul J. Meakin, Paul S. Baxter, Sean McKay, Owen Dando, Michael L.J. Ashford, Irina Gazaryan, John D. Hayes, Giles E. Hardingham
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102158- (2021)
The transcription factor Nrf2 is a stress-responsive master regulator of antioxidant, detoxification and proteostasis genes. In astrocytes, Nrf2-dependent gene expression drives cell-autonomous cytoprotection and also non-cell-autonomous protection o
Externí odkaz:
https://doaj.org/article/bfac644fbd9a4a15bd392002c220b8e0
Autor:
Abeer A. Alabdullah, Basma Al-Abdulaziz, Hanan Alsalem, Amna Magrashi, Subramanian M. Pulicat, Amer A. Almzroua, Falah Almohanna, Abdullah Mohamed Assiri, Nada A. Al Tassan, Bashayer R. Al-Mubarak
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective Delivery of constructs for silencing or over-expressing genes or their modified versions is a crucial step for studying neuronal cell biology. Therefore, efficient transfection is important for the success of these experimental tec
Externí odkaz:
https://doaj.org/article/eead3479070b41148e82426a27eddf8e
Autor:
Faris M. Abomelha, Hesham AlDhalaan, Mohammad Ghaziuddin, Nada A. Al-Tassan, Bashayer R. Al-Mubarak
Publikováno v:
Genes. 13(9)
Even in the era of information “prosperity” in the form of databases and registries that compile a wealth of data, information about ASD and ADHD remains scattered and disconnected. These data systems are powerful tools that can inform decision-m
Publikováno v:
MEJ. Mansoura Engineering Journal. 32:58-69
In this work, a nonlinear model representing the dynamics of the container sway of a gantry crane is derived. The dynamics of the induction motors are also taken into consideration in addition to the simultaneous travelling, trolley and housing motio
Autor:
Bashayer R Al-Mubarak, Saeed A Bohlega, Thamer S Alkhairallah, Amna I Magrashi, Maha I AlTurki, Dania S Khalil, Basma S AlAbdulaziz, Hussam Abou Al-Shaar, Abeer E Mustafa, Eman A Alyemni, Bashayer A Alsaffar, Asma I Tahir, Nada A Al Tassan
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135950 (2015)
Parkinson's disease (PD) is one of the major causes of parkinsonism syndrome. Its characteristic motor symptoms are attributable to dopaminergic neurons loss in the midbrain. Genetic advances have highlighted underlying molecular mechanisms and provi
Externí odkaz:
https://doaj.org/article/f62aea7f0947470ea1bff78fbff8926b
Autor:
Monica Kraft, Nicole Pavelka, R. Al Mubarak, Hong Wei Chu, Max A. Seibold, Dennis R. Voelker, Julie G. Ledford, Liwu Li, Azzeddine Dakhama
Publikováno v:
A21. ADVANCES IN ASTHMA PATHOGENESIS.
Autor:
Bashayer R. Al-Mubarak, Amer A. Almzroua, Nada A. Al Tassan, Abdullah Mohamed Assiri, Falah Al-Mohanna, Abeer A. Alabdullah, Hanan Alsalem, Basma S. AlAbdulaziz, Amna Magrashi, Subramanian M. Pulicat
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
BMC Research Notes
BMC Research Notes
Objective Delivery of constructs for silencing or over-expressing genes or their modified versions is a crucial step for studying neuronal cell biology. Therefore, efficient transfection is important for the success of these experimental techniques e
Autor:
Abeer E. Mustafa, Batoul Baz, Amna Magrashi, Tariq Faquih, Eman A.A. Al Yemni, Jameela Shinwari, Dorota Monies, Shazia Subhani, Nada Al-Tassan, Amjad Jabaan, Basma S. AlAbdulaziz, Wafa Ali, Mohamed Abouelhoda, Ewa Goljan, Bashayer R. Al-Mubarak, Thamer Alkhairallah, Mohamed H Al-Hamed, Renad Albar, Saeed Bohlega
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Genetic studies of the familial forms of Parkinson’s disease (PD) have identified a number of causative genes with an established role in its pathogenesis. These genes only explain a fraction of the diagnosed cases. The emergence of Next Generation
Autor:
Abeer E, Mustafa, Tariq, Faquih, Batoul, Baz, Rana, Kattan, Abdulelah, Al-Issa, Asma I, Tahir, Faiqa, Imtiaz, Khushnooda, Ramzan, Moeenaldeen, Al-Sayed, Mohammed, Alowain, Zuhair, Al-Hassnan, Hamad, Al-Zaidan, Mohamed, Abouelhoda, Bashayer R, Al-Mubarak, Nada A, Al Tassan
Publikováno v:
Genes
Quick and accurate molecular testing is necessary for the better management of many inherited diseases. Recent technological advances in various next generation sequencing (NGS) platforms, such as target panel-based sequencing, has enabled comprehens