Zobrazeno 1 - 10
of 376
pro vyhledávání: '"R. Adron Harris"'
Autor:
Barbara J. Mason, David Estey, Amanda Roberts, Giordano de Guglielmo, Olivier George, John Light, Mike Stoolmiller, Susan Quello, Michael Skinner, Farhad Shadan, Adnan Begovic, Mark C. Kyle, R. Adron Harris
Publikováno v:
Neurobiology of Stress, Vol 29, Iss , Pp 100604- (2024)
Alcohol Use Disorder (AUD) is a chronic relapsing disorder affecting an estimated 283 million individuals worldwide, with substantial health and economic consequences. Peroxisome proliferator-activated receptors (PPARs), particularly PPAR-α and PPAR
Externí odkaz:
https://doaj.org/article/d712f48a4d8d46ca9c970201760b2cc2
Autor:
Brent R. Kisby, Sean P. Farris, Michelle M. McManus, Florence P. Varodayan, Marisa Roberto, R. Adron Harris, Igor Ponomarev
Publikováno v:
Brain Sciences, Vol 11, Iss 9, p 1149 (2021)
Alcohol dependence is associated with adverse consequences of alcohol (ethanol) use and is evident in most severe cases of alcohol use disorder (AUD). The central nucleus of the amygdala (CeA) plays a critical role in the development of alcohol depen
Externí odkaz:
https://doaj.org/article/86e86662e299475c820d57fe9281bc4d
Autor:
Cecilia M. Borghese, Melissa Herman, Lawrence D. Snell, Keri J. Lawrence, Hyun-Young Lee, Donald S. Backos, Lauren A. Vanderlinden, R. Adron Harris, Marisa Roberto, Paula L. Hoffman, Boris Tabakoff
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Aminoquinoline derivatives were evaluated against a panel of receptors/channels/transporters in radioligand binding experiments. One of these derivatives (DCUK-OEt) displayed micromolar affinity for brain γ-aminobutyric acid type A (GABAA)
Externí odkaz:
https://doaj.org/article/deb9d0e8116a4679aa8f5c369a838e42
Autor:
Sarah A. Wolfe, Emily R. Workman, Chelcie F. Heaney, Farr Niere, Sanjeev Namjoshi, Luisa P. Cacheaux, Sean P. Farris, Michael R. Drew, Boris V. Zemelman, R. Adron Harris, Kimberly F. Raab-Graham
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Alcohol is thought to lead to neuroadaptive changes, although the underlying molecular mechanisms are unclear. Here, the authors find ethanol treatment alters GABAB-receptor expression via fragile-X mental retardation protein in mice, leading to anti
Externí odkaz:
https://doaj.org/article/e5cec5c74cef40f9abc05988792bd8e3
Autor:
Laura B. Ferguson, Lingling Zhang, Shi Wang, Courtney Bridges, R. Adron Harris, Igor Ponomarev
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Peroxisome proliferator activated receptors (PPARs) are nuclear hormone receptors that act as transcription factors in response to endogenous lipid messengers. The fibrates and thiazolidinediones are synthetic PPAR agonists used clinically to treat d
Externí odkaz:
https://doaj.org/article/73040b37a629402ea74685a44c9f838c
Publikováno v:
F1000Research, Vol 6 (2017)
Background: Innate immune signaling in the brain has emerged as a contributor to many central nervous system (CNS) pathologies, including mood disorders, neurodegenerative disorders, neurodevelopmental disorders, and addiction. Toll-like receptors (T
Externí odkaz:
https://doaj.org/article/48e64853ded04866b832fb2ba1fa13b6
Autor:
S. John Mihic, R. Adron Harris
Publikováno v:
BioTechniques, Vol 20, Iss 5, Pp 802-804 (1996)
Externí odkaz:
https://doaj.org/article/d073c268db0e46d3ad7e56e6283abf95
Autor:
Sean P. Farris, Cecilia M. Borghese, Elizabeth A. Osterndorff-Kahanek, Heather C. Aziz, Regina A. Mangieri, Yuri A. Blednov, Gregg E. Homanics, R. Adron Harris, R. Dayne Mayfield
Publikováno v:
Alcohol. 109:67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d7c0a849ca19efc39e49806c92af900
https://doi.org/10.1016/j.alcohol.2023.03.009
https://doi.org/10.1016/j.alcohol.2023.03.009
Autor:
Hugo R. Arias, Cecilia M. Borghese, Allison L. Germann, Spencer R. Pierce, Alessandro Bonardi, Alessio Nocentini, Paola Gratteri, Thanvi M. Thodati, Natalie J. Lim, R. Adron Harris, Gustav Akk
Publikováno v:
Biochem Pharmacol
(+)-Catharanthine, a coronaridine congener, potentiates the γ-aminobutyric acid type A receptor (GABA(A)R) and induces sedation through a non-benzodiazepine mechanism, but the specific site of action and intrinsic mechanism have not been defined. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf9b9afbb6d6267fc91a716f243787d
https://europepmc.org/articles/PMC9178925/
https://europepmc.org/articles/PMC9178925/
Autor:
Moatasem M. Azzam, Sonia Mason, Adriana DaCosta, R. Dayne Mayfield, Yuri A. Blednov, Robert O. Messing, R. Adron Harris, Anna S. Warden
Publikováno v:
Brain, Behavior, and Immunity. 77:66-76
Although there are sex differences in the effects of alcohol on immune responses, it is unclear if sex differences in immune response can influence drinking behavior. Activation of toll-like receptor 3 (TLR3) by polyinosinic:polycytidylic acid (poly(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2048efd2ba802bd38d5a5c258a17f319
https://doi.org/10.1016/j.bbi.2018.12.006
https://doi.org/10.1016/j.bbi.2018.12.006