Zobrazeno 1 - 10 of 181 pro vyhledávání: '"R. A. Sparks"'
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Akademický článek
Sidestream Smoke Extracts from Harm-Reduction and Conventional Camel Cigarettes Inhibit Osteogenic Differentiation via Oxidative Stress and Differential Activation of intrinsic Apoptotic Pathways
Autor: Nicole R. L. Sparks, Lauren M. Walker, Steven R. Sera, Joseph V. Madrid, Michael Hanna, Edward C. Dominguez, Nicole I. zur Nieden
Publikováno v: Antioxidants, Vol 11, Iss 12, p 2474 (2022)
Epidemiological studies suggest cigarette smoking as a probable environmental factor for a variety of congenital anomalies, including low bone mass, increased fracture risk and poor skeletal health. Human and animal in vitro models have confirmed hyp
Externí odkaz: https://doaj.org/article/07c1209263284e1a89ffab36c48c4aac
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Exposure to Cigarette Smoke Impedes Human Osteoblast Differentiation Independently of Nicotine
Autor: Ivann K C Martinez, Nicole R L Sparks, J V Madrid, Prue Talbot, Nicole I zur Nieden
Publikováno v: Nicotine & Tobacco Research. 24:1921-1926
Introduction Tobacco smoking has been implicated in an array of adverse health outcomes, including those that affect adult bone. However, little is known about the impact of tobacco products on developing bone tissue as it develops in the embryo. Aim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd35e7341e93b404c56c9f6ab791bf06
https://doi.org/10.1093/ntr/ntac144
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Nanchangmycin regulates FYN, FAK and ERK to control the fibrotic activity of hepatic stellate cells
Autor: S. J. Ho Sui, Sean P. Moran, Alan C. Mullen, D. Wrobel, Rory Kirchner, Juxiang Chen, Joshua V. Pondick, M. Bieler, J. F. Doerner, R. P. Sparks, Jörg F. Rippmann, Wei Li, Raza-Ur Rahman, Lorena Pantano, Chi-Kuang Sun
Chronic liver injury causes fibrosis, characterized by the formation of scar tissue resulting from excessive accumulation of extracellular matrix (ECM) proteins. Hepatic stellate cell (HSC) myofibroblasts are the primary cell type responsible for liv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5a5f99395e9e235a46d5a30621b0885
https://doi.org/10.1101/2021.10.08.463221
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The inner membrane protein YhiM is necessary for Escherichia coli growth at high temperatures and low osmolarity
Autor: M. A. Evans, M. A. Anderson, R. L. Sparks-Thissen, M. D. Mann
Publikováno v: Archives of Microbiology. 199:171-175
To survive, Escherichia coli must be able to survive in rapidly changing environmental conditions including changes in temperature and osmolarity. We have studied the role of the inner membrane protein YhiM in changing environmental conditions. Our d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a9d77fbed154c26479e69a80f4f4cd
https://doi.org/10.1007/s00203-016-1288-3
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10
Human Pluripotent Stem Cells to Assess Developmental Toxicity in the Osteogenic Lineage
Autor: Joseph V, Madrid, Steven R, Sera, Nicole R L, Sparks, Nicole I, Zur Nieden
Publikováno v: Methods in molecular biology (Clifton, N.J.). 1797
Musculoskeletal birth defects are frequent, yet their causes remain insufficiently investigated. Aside from genetic factors, exposure to environmental toxicants is suspected to contribute to the etiology of skeletal malformations. However, most chemi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::adc0ec378cf64c1f03a6fd1086589e2c
https://pubmed.ncbi.nlm.nih.gov/29896689
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