Zobrazeno 1 - 10
of 1 794
pro vyhledávání: '"R. A. RUSSELL"'
Publikováno v:
Health Expectations, Vol 27, Iss 5, Pp n/a-n/a (2024)
ABSTRACT Background Multiple sclerosis (MS) is a complex immune‐mediated disease with no currently known cure. There is growing evidence to support the role of diet in reducing some of the symptoms and disease progression in MS, and we previously d
Externí odkaz:
https://doaj.org/article/f9ec459208b74b6aab2b99152f60a1c4
Autor:
Simon Butterworth, Francesca Torelli, Eloise J Lockyer, Jeanette Wagener, Ok-Ryul Song, Malgorzata Broncel, Matt R G Russell, Aline Cristina A Moreira-Souza, Joanna C Young, Moritz Treeck
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1011021 (2022)
Toxoplasma gondii is an intracellular parasite that can infect many host species and is a cause of significant human morbidity worldwide. T. gondii secretes a diverse array of effector proteins into the host cell which are critical for infection. The
Externí odkaz:
https://doaj.org/article/1ef7567a322246b68d3ab5f125e50e7c
Autor:
Gábor M. Mórotz, Sandra M. Martín-Guerrero, Andrea Markovinovic, Sebastien Paillusson, Matthew R. G. Russell, Pedro M. Pereira Machado, Roland A. Fleck, Wendy Noble, Christopher C.J. Miller
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Signaling between the endoplasmic reticulum (ER) and mitochondria regulates a number of fundamental physiological processes. This signaling involves close physical contacts between the two organelles that are mediated by the VAPB-PTPIP51 ″tethering
Externí odkaz:
https://doaj.org/article/39eaf584213b4fd8b1fbbb27b0353415
Autor:
Joanna C. Young, Malgorzata Broncel, Helena Teague, Matt R. G. Russell, Olivia L. McGovern, Matt Renshaw, David Frith, Ambrosius P. Snijders, Lucy Collinson, Vern B. Carruthers, Sarah E. Ewald, Moritz Treeck
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT The intracellular parasite Toxoplasma gondii resides within a membrane-bound parasitophorous vacuole (PV) and secretes an array of proteins to establish this replicative niche. It has been shown previously that Toxoplasma secretes kinases an
Externí odkaz:
https://doaj.org/article/8ec188a235d64c0fb4aaa3600be59d6f
Autor:
V Svolos, R Hansen, R K Russell, D R Gaya, J P Seenan, J Macdonald, D Wilson, P Henderson, S Din, G T Ho, C Quince, U Z Ijaz, S Milling, B Nichols, R Papadopoulou, S McKirdy, L Gervais, S Shields, K Gerasimidis
Publikováno v:
Journal of Crohn's and Colitis. 17:i513-i515
Background Treatment with the CD-TREAT solid food diet improves disease activity indices, faecal calprotectin (FCAL) levels and quality of life in adults and children with active Crohn’s disease (CD); particularly in patients who adhere to the diet
Autor:
K Gerasimidis, B Nichols, R Papadopoulou, U Ijaz, R Rajendran, C Quince, R K Russell, R Hansen, G Ramage
Publikováno v:
Journal of Crohn's and Colitis. 17:i122-i124
Background The fungal community (mycobiome) and immunological responses to specific fungi have been implicated in Crohn’s disease (CD) pathogenesis and its phenotype. There is limited data on profiling the mycobiome in paediatric CD and how it chan
Autor:
Emma S Sherling, Abigail J Perrin, Ellen Knuepfer, Matthew R G Russell, Lucy M Collinson, Louis H Miller, Michael J Blackman
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008049 (2019)
The malaria parasite Plasmodium falciparum invades, replicates within and destroys red blood cells in an asexual blood stage life cycle that is responsible for clinical disease and crucial for parasite propagation. Invasive malaria merozoites possess
Externí odkaz:
https://doaj.org/article/2489d6a65cf34f7da3cb255cdebd8f41
Autor:
Abigail J. Perrin, Christine R. Collins, Matthew R. G. Russell, Lucy M. Collinson, David A. Baker, Michael J. Blackman
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Apicomplexa are obligate intracellular parasites that actively invade, replicate within, and egress from host cells. The parasite actinomyosin-based molecular motor complex (often referred to as the glideosome) is considered an important med
Externí odkaz:
https://doaj.org/article/093ba9dc06054e14aab1802c0b6e0989
Autor:
O Atia, Z Shavit-Brunschwig, A Quteineh, R Lev-Tzion, R Stein, E Broide, D Urlep, J Hyams, M Aloi, D S Shouval, A Assa, S Hussey, J Markowitz, A Yerushalmy, E Miele, R K Russell, D Turner
Publikováno v:
Journal of Crohn's and Colitis. 17:i904-i905
Background We previously reported the effectiveness of vedolizumab (VDZ) to induce remission in children with CD and UC enrolled in the prospective,multicenter VEDOKIDS study.In this extended analysis,we aimed to explore the effectiveness and safety
Publikováno v:
Journal of Crohn's and Colitis. 17:i956-i957
Background Whilst the high burden of mental health comorbidity in people with inflammatory bowel disease (IBD) is now being recognised, less is known about the additional impacts of having concurrent IBD and a mental health condition, especially in c