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ChemInform Abstract: SOLVENT EFFECTS ON THE VISIBLE SPECTRA OF NITROXIDES AND RELATION TO NITROGEN HYPERFINE SPLITTING CONSTANTS. NONEMPIRICAL POLARITY SCALES FOR APROTIC AND HYDROXYLIC SOLVENTS

Autor: P. MUKERJEE, C. RAMACHANDRAN, R. A. PYTER

Publikováno v: Chemischer Informationsdienst. 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12abf878d6cf728cceded16fd7abc7ce
https://doi.org/10.1002/chin.198244042

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ChemInform Abstract: Azido Glycols: Potent, Low Molecular Weight Renin Inhibitors Containing an Unusual Post Scissile Site Residue

Autor: Hugh N. Nellans, Keith W. Woods, Jerome Cohen, D. J. Hoffman, Saul H. Rosenberg, Jacob J. Plattner, R. A. Pyter, Thomas J. Perun, S. G. Spanton, Herman H. Stein, H. D. Kleinert, David A. Egan

Publikováno v: ChemInform. 20

Basic hydrolysis of the oxazolidinone (I) followed by N-protection produces the allylic alcohol (IIb) which is converted to the diol (IV) by hydroboration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7dd627880ac5a7e98909f15287167f6
https://doi.org/10.1002/chin.198949112

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Stability of methylprednisolone sodium succinate in 5% dextrose and 0.9% sodium chloride injections

Autor: R A, Pyter, L C, Hsu, J D, Buddenhagen

Publikováno v: American journal of hospital pharmacy. 40(8)

The stability of methylprednisolone sodium succinate (MPSS) in two intravenous solutions was studied. Using a factorial design, solutions consisting of 1% or 5% (w/w) free methylprednisolone in 5% dextrose injection or 0.9% sodium chloride injection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94f12a6350fefdc6da88c0204f5e6d2a
https://pubmed.ncbi.nlm.nih.gov/6351604

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Azido glycols: potent, low molecular weight renin inhibitors containing an unusual post scissile site residue

Autor: Keith W. Woods, Jerry Cohen, R. A. Pyter, Hollis D. Kleinert, Saul H. Rosenberg, S. G. Spanton, Daniel J. Hoffman, Hugh N. Nellans, Herman H. Stein, David A. Egan

Publikováno v: Journal of medicinal chemistry. 32(6)

Azidomethyl-substituted 1,2- and 1,3-diols were prepared from Boc-cyclohexylalanal and evaluated as transition state analogue renin inhibitors, leading to the development of a small (MW less than 600), nanomolar inhibitor. Remarkable aqueous solubili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f51b5c85a5a364de739e6224739821c
https://pubmed.ncbi.nlm.nih.gov/2657067

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