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Super-resolution imaging of structure, molecular composition, and stability of single oligonucleotide polyplexes

Autor: Natalia Feiner-Gracia, Lorenzo Albertazzi, R. Alis Olea, Najoua El Boujnouni, Roland Brock, Alexander H. van Asbeck, Robert Fitzner

Publikováno v: Nano Letters, 19(5), 2784-2792. American Chemical Society
Nano Letters
Nano Letters, 19, 5, pp. 2784-2792
Nano Letters, 19, 2784-2792

[Image: see text] The successful application of gene therapy relies on the development of safe and efficient delivery vectors. Cationic polymers such as cell-penetrating peptides (CPPs) can condense genetic material into nanoscale particles, called p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4ad3a1eb6a79202d250c919458da5a
http://www.scopus.com/inward/record.url?scp=85065546776&partnerID=8YFLogxK

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Membrane permeation of arginine-rich cell-penetrating peptides independent of transmembrane potential as a function of lipid composition and membrane fluidity

Autor: Rike Wallbrecher, R. Alis Olea, Petra H. M. Bovee-Geurts, Tobias Ackels, Merel J. W. Adjobo-Hermans, Jürgen Schiller, Marc Spehr, Marco J. Klein, Anne S. Ulrich, Caillon Lucie, Toin H. van Kuppevelt, Roland Brock

Publikováno v: Journal of Controlled Release, 256, pp. 68-78
Journal of controlled release, 256, 68-78
Journal of Controlled Release, 256, 68-78
Journal of controlled release 256, 68-78 (2017). doi:10.1016/j.jconrel.2017.04.013

Journal of controlled release 256, 68-78 (2017). doi:10.1016/j.jconrel.2017.04.013
Published by Elsevier, New York, NY [u.a.]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6c4e7cc40f2a79409c7e3fc4099c56
https://hdl.handle.net/2066/174429

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Corioamnionitis subclínica: un reto diagnóstico. A propósito de un caso

Autor: M. Sancha Naranjo, G. Vegas García de Yébenes, D. Abehsera Davó, F. Magdaleno Dans, R. Alcedo Olea, A González González

Publikováno v: Clínica e Investigación en Ginecología y Obstetricia. 41:189-192

Resumen El diagnostico de la corioamnionitis subclinica en pacientes con rotura prematura de membranas en gestacion pretermino supone un reto. Cuando se descarta infeccion intraamniotica mediante amniocentesis, no esta claro, dentro del manejo expect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f117b9729d7c4e872e5c59a0f1c8cf83
https://doi.org/10.1016/j.gine.2013.05.004

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[Untitled]

Autor: Vera Pawlowsky-Glahn, Josep Antoni Martín-Fernández, R. A. Olea-Meneses

Publikováno v: Mathematical Geology. 33:889-909

The additive logratio (alr) transformation has been used in several case studies to predict regionalized compositions using standard geostatistical estimation methods such as ordinary kriging and ordinary cokriging. It is a simple method that allows

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b2ef3ffdeb9fd3e461bb08c88d9cb9f
https://doi.org/10.1023/a:1012293922142

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Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. I. Regulatory volume decrease

Autor: Julio Morán, R. Sánchez Olea, D. Miranda, Herminia Pasantes-Morales

Publikováno v: American Journal of Physiology-Cell Physiology. 272:C1798-C1803

Exposure of NIH/3T3 fibroblasts not expressing P-glycoprotein to 50, 30, 20, and 10% hyposmotic solutions led to cell volume increases of 70, 32, 21, and 12%, respectively. After swelling, NIH/3T3 cells exhibited regulatory volume decrease (RVD), att

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d50ca696bcb0dd3b052f1124e81bd9
https://doi.org/10.1152/ajpcell.1997.272.6.c1798

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Cl channel blockers inhibit the volume-activated efflux of Cl and taurine in cultured neurons

Autor: R. Sanchez-Olea, Oscar Jerez García, Herminia Pasantes-Morales, M. Morales

Publikováno v: American Journal of Physiology-Cell Physiology. 270:C1703-C1708

The effects of the Cl channel blockers 5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB), 1,9-dideoxyforskolin (DDF), dipyridamole, and niflumic acid and of the polyunsaturated fatty acids arachidonic, linolenic, and linoleic acids on regulatory vol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252a35e7fe33edef57f285fea818e6f4
https://doi.org/10.1152/ajpcell.1996.270.6.c1703

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Inhibition of volume regulation and efflux of osmoregulatory amino acids by blockers of Cl− transport in cultured astrocytes

Autor: R. Sanchez-Olea, Julio Morán, Herminia Pasantes-Morales, Claudia Peña

Publikováno v: Neuroscience Letters. 156:141-144

Regulatory volume decrease (RVD) in astrocytes was inhibited by the Cl- exchanger blockers 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), dipyridamole and niflumic acid but not by the Cl- channel inhibitors diphenylamine-2-carboxylate (DPC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7affe45d51ee43d02a2b336f37b8c57
https://doi.org/10.1016/0304-3940(93)90458-w

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Neurons respond to hyposmotic conditions by an increase in intracellular free calcium

Autor: R. Sanchez-Olea, Arne Schousboe, Herminia Pasantes-Morales

Publikováno v: Neurochemical Research. 18:147-152

The effect of hyposmotic conditions on the concentration of intracellular free calcium ([Ca2+]i) was studied in cultured cerebellar granule cells and cerebral cortical neurons after loading of the cells with the fluorescent Ca2+ chelator Fluo-3. It w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edda70e0127ae8bbb748e413699effa
https://doi.org/10.1007/bf01474677

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Hyposmolarity-induced taurine release in cerebellar granule cells is associated with diffusion and not with high-affinity transport

Autor: R. Sánchez Olea, Julio Morán, Herminia Pasantes-Morales, Arne Schousboe

Publikováno v: Journal of Neuroscience Research. 30:661-665

The effects of hyposmotic conditions on taurine uptake and release were studied in mice cultured cerebellar granule cells. The effect of DIDS (4,4′-diisothiocyanatostilbene-2,2′-disulfonate) and of the divalent cations Mg++ and Mn++ on the hyposm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9e4e9c378b4a325064ee9db080767fa
https://doi.org/10.1002/jnr.490300409

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Hyposmolarity-activated fluxes of taurine in astrocytes are mediated by diffusion

Autor: R. Sanchez-Olea, Arne Schousboe, Herminia Pasantes-Morales, Julio Morán

Publikováno v: Neuroscience Letters. 130:233-236

In order to obtain information about the mechanism responsible for swelling associated taurine release in astrocytes, the kinetics of taurine uptake in cultured astrocytes from mouse cerebral cortex was studied under isosmotic and hyposmotic (50% osm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cd295f798afc93560d8958c9cdf576
https://doi.org/10.1016/0304-3940(91)90404-h

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