Zobrazeno 1 - 10
of 34
pro vyhledávání: '"R. A. Knyazev"'
Autor:
E. B. Menshchikova, R. A. Knyazev, N. V. Trifonova, N. A. Deeva, A. R. Kolpakov, L. P. Lidia P. Romakh, N. V. Kandalintseva
Publikováno v:
Сибирский научный медицинский журнал, Vol 43, Iss 5, Pp 108-117 (2023)
The antitumor antibiotic doxorubicin, a representative of a large group of anthriacyclines, is widely and quite effectively used to treat patients with malignant neoplasms. The aim of this study was to study the effect of TS-13, a synthetic phenolic
Externí odkaz:
https://doaj.org/article/c5229a4af04b43fb9232eac5a11fa178
Publikováno v:
Сибирский научный медицинский журнал, Vol 43, Iss 4, Pp 91-96 (2023)
The aim of this study was to investigate the possibility of using apolipoprotein A-I (apo A-I) as a transport form of the green fluorescent protein (GFP) gene into rat hepatocytes.Material and methods. A culture of isolated rat hepatocytes was used a
Externí odkaz:
https://doaj.org/article/c5af514ec20a45f699f4e07052db881b
Autor:
L. M. Polyakov, R. A. Knyazev, N. V. Trifonova, M. V. Kotova, E. I. Solovyova, A. V. Ryabchenko
Publikováno v:
Атеросклероз, Vol 16, Iss 4, Pp 13-17 (2020)
This work presents the characteristics of the catalytic activity of hydroxylation of benzo[a] pyrene (B[a]P) in rat liver microsomes using plasma lipoproteins (LP) (VLDL, LDL, HDL) as transport forms of B[a]P. The aim of the study was: to study the e
Externí odkaz:
https://doaj.org/article/f6f12d58f58d4af985ac868145b2ba49
Autor:
L. M. Polyakov, R. A. Knyazev, N. V. Trifonova, M. V. Kotova, E. I. Solovyova, A. V. Ryabchenko
Publikováno v:
Атеросклероз, Vol 16, Iss 3, Pp 45-52 (2020)
Interest in the study of high density lipoproteins (HDL) is associated with the functional activity of these particles, which, first of all, determines their antiatherogenic properties. The main biological role of HDL is the «reverse» transport of
Externí odkaz:
https://doaj.org/article/a40f08efea8446db9a83e3069aae8f31
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 6, Pp 31-36 (2020)
The paper deals with the functions of the main classes of blood plasma lipoproteins (LP) that are associated with the transport of cholesterol esters included in their composition. The aim of the study was to investigate the features of the uptake of
Externí odkaz:
https://doaj.org/article/b6c309f89662460aa1a1d67b4ba254d6
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 4, Pp 30-36 (2019)
The paper discusses the transport functions of the main classes of blood plasma lipoproteins (LP) that are not associated with the metabolism of lipids that make up their composition. The aim of the study was to study the ability of various plasma LP
Externí odkaz:
https://doaj.org/article/695164fc55fb45fda18f39aac4acd89c
Publikováno v:
Сибирский научный медицинский журнал, Vol 38, Iss 6, Pp 29-34 (2019)
With the widespread development of the phenomenon of RNA interference, currently, researchers are puzzled to obtain effective carriers of small interfering RNA (siRNA). Previously, we obtained a modified recombinant polypeptide based on human apolipo
Externí odkaz:
https://doaj.org/article/04f4ac3e75eb4d31acc9f27f0b34b60a
Publikováno v:
Сибирский научный медицинский журнал, Vol 38, Iss 6, Pp 13-18 (2019)
The catalytic domain of the nuclear inclusion protein of the tobacco etch virus protease, TEVp, is used for the cleavage of artificial fusion polypeptides. However, the production of a recombinant enzyme has certain difficulties, such as a low yield
Externí odkaz:
https://doaj.org/article/b5a62093c83a410884dcaef83dca5768
Publikováno v:
Сибирский онкологический журнал, Vol 17, Iss 6, Pp 64-69 (2019)
Introduction. The development of new and highly effective antitumor therapy is one of the priorities of pharmacology. The paper presents one of the solutions to the problem related to the development of transport forms of antitumor drugs.The aim of t
Externí odkaz:
https://doaj.org/article/49abf8df11c24369b6824475cd37f1ad
Publikováno v:
Сибирский онкологический журнал, Vol 0, Iss 3, Pp 43-46 (2016)
Studies were conducted using ascetic HA-1 hepatomas and ascitic Ehrlich’s carcinoma cells. After passage of cells in mice, cell culture containing tumor-associated macrophages was studied. It was shown that the very low-density lipoprotein (VLDL)-c
Externí odkaz:
https://doaj.org/article/3ff90b75178f4723a257bc0a61a4d495