Zobrazeno 1 - 10
of 37
pro vyhledávání: '"R. A. Janis"'
Autor:
M R N Christine Bluhm, Stephen C. Hammill, Paul A. Friedman, Anita Wokhlu, Thomas M. Munger, Win-Kuang Shen, H R N Kristi Monahan, Samuel J. Asirvatham, David O. Hodge, Peter A. Brady, Yong-Mei Cha, M R N Janis Haroldson, Douglas L. Packer
Publikováno v:
Journal of cardiovascular electrophysiology. 21(10)
Ablation eliminates atrial fibrillation (AF) in studies with 1 year follow-up, but very late recurrences may compromise long-term efficacy. In a large cohort, we sought to describe the determinants of delayed recurrence after AF ablation.Seven hundre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b8836315e8fb021afd3aff7e6cdfd6
https://pubmed.ncbi.nlm.nih.gov/20500237
https://pubmed.ncbi.nlm.nih.gov/20500237
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 257(3)
Binding of the hypoglycemic sulfonylurea, [3H]glyburide, to crude membrane fractions from brain, heart and smooth (intestinal) muscle was saturable, linear with protein concentration and reversible. Saturation analysis revealed high affinity sites (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dfba237ce697d4655a02078d3405e0b
https://pubmed.ncbi.nlm.nih.gov/1904493
https://pubmed.ncbi.nlm.nih.gov/1904493
Autor:
Edwin E. Daniel, R. A. Janis
Publikováno v:
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology. 1:695-729
Calcium (Ca) regulation in the uterus is reviewed. The topics included are 1) Ca content of myometrium (normal Ca content effects of various proceedings on Ca content effect of hormonal state on Ca content); 2) uterine Ca fluxes (use of compartmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7ba8cbe5cb03c231e6911844dae51b
https://doi.org/10.1016/0306-039x(75)90025-2
https://doi.org/10.1016/0306-039x(75)90025-2
Autor:
R. A. Janis, D. J. Triggle
Publikováno v:
Journal of Medicinal Chemistry. 26:775-785
Toward the beginning of this Perspective we posed a number of questions to be answered concerning the Ca2+ channel antagonists. Biochemical, chemical, clinical, pharmacological, and physiological studies collectively support the conclusion that this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ffb3156bcc9b31629aab0695be5e3ad
https://doi.org/10.1021/jm00360a001
https://doi.org/10.1021/jm00360a001
Publikováno v:
Circulation Research. 40:299-305
Spontaneously hypertensive rats (SHR) and two strains of normotensive rats were compared with respect to enzymatic activities and calcium accumulation of plasma membrane and endoplasmic reticulum enriched fractions from their mesenteric arteries. Inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf60dbf24f69d18d6821d85348a12bd
https://doi.org/10.1161/01.res.40.3.299
https://doi.org/10.1161/01.res.40.3.299
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 65:1452-1460
Binding of [3H]nitrendipine, [3H]nimodipine, and (+)[3H]PN 200-110 to microsomal preparations of guinea pig smooth and cardiac muscle and brain synaptosomes revealed high affinity interaction with KD values in the sequence, (+)PN 200-110 > nitrendipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9adc075d2b90e65f059d437ea95586b
https://doi.org/10.1139/y87-228
https://doi.org/10.1139/y87-228
Publikováno v:
Circulation Research. 39:133-140
Subcellular fractions were obtained from aortas and ventricles of 6-month-old spontaneously hypertensive and normotensive Wistar rats by the use of differential and sucrose density gradient centrifugation. These preparations were studied to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cb14c00ca14ba7c747998cc5603afb
https://doi.org/10.1161/01.res.39.1.133
https://doi.org/10.1161/01.res.39.1.133
Publikováno v:
Journal of Vascular Research. 13:279-292
A method for isolating a plasma membrane-enriched fraction and other subcellular fractions from rat mesenteric arteries by the use of a discontinuous sucrose density gradient is described. Electron microscopy showed both plasma membrane and endoplasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb14ee1bd1b710ae0a8e66ca0a1a8c5
https://doi.org/10.1159/000158098
https://doi.org/10.1159/000158098
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 365:171-176
A subcellular fraction enriched in sarcolemma was isolated by differential and sucrose gradient centrifugation from human myometrium. The Ca2+ binding characteristics of this fraction were compared to that of mitochondria and microsomes that were iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f1a7ba740451a613ea27f86fe17d02
https://doi.org/10.1007/bf01067015
https://doi.org/10.1007/bf01067015
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 58:243-248
The effects of oxytocin and methacholine on cyclic nucleotide levels in estrogen-primed rabbit myometrium were studied in the presence and absence of 1-methyl-3-isobutyl xanthine (MIX), a phosphodiesterase inhibitor. In the absence of MIX, methacholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1cb5bafd526adcf9cfcebfe881caa6
https://doi.org/10.1139/y80-042
https://doi.org/10.1139/y80-042