Zobrazeno 1 - 10
of 84
pro vyhledávání: '"R. A. J. Challiss"'
Autor:
Julian W. Gardner, Shannon B. Olsson, Johannes G.E. Gardeniers, Angel Guerrero, Marina Cole, Bill S. Hansson, R. A. J. Challiss, Tim Pearce
Publikováno v:
Bioinspiration & biomimetics. 10(4)
There is an ever-increasing demand for data to be embedded in our environment at ever-decreasing temporal and spatial scales. Whilst current communication and storage technologies generally exploit the electromagnetic properties of media, chemistry o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1420219a793564dc76ed2d5c6ad4c86
http://www.scopus.com/inward/record.url?scp=84940399449&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=84940399449&partnerID=8YFLogxK
Publikováno v:
Journal of Neurochemistry. 63:2369-2372
The ability of receptors coupled to phosphoinositide turnover to evoke accumulation of inositol 1,4,5-trisphosphate (InsP3) over extended incubation periods, and consequently to affect the level of InsP3 receptor expression, was studied in cultured c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55904412c9d44dcfcf3e66801efb580
https://doi.org/10.1046/j.1471-4159.1994.63062369.x
https://doi.org/10.1046/j.1471-4159.1994.63062369.x
Publikováno v:
Journal of Neurochemistry. 70:1772-1775
Stable expression of the human type 1alpha metabotropic glutamate (mGlu 1alpha) receptor was achieved in Chinese hamster ovary cells using an isopropyl-beta-D-thiogalactoside (IPTG)-repressible expression system. Treatment of the cells with IPTG resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab554d5e8ed84c30f8840866971fb413
https://doi.org/10.1046/j.1471-4159.1998.70041772.x
https://doi.org/10.1046/j.1471-4159.1998.70041772.x
Publikováno v:
Neuropharmacology. 38:1485-1492
The potential role of N-linked glycosylation of the human type 1 alpha metabotropic glutamate (mGlu1 alpha) receptor was studied in a recombinant, inducible expression system, where receptor expression was induced in the absence and presence of tunic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6e37df56a6944a164db6c18be3f192
https://doi.org/10.1016/s0028-3908(99)00099-4
https://doi.org/10.1016/s0028-3908(99)00099-4
Publikováno v:
Biochemical Journal. 338:619-628
Extracellular signal-regulated kinases (ERKs) and c-Jun N-terminal kinases (JNKs, or stress-activated protein kinases) are activated by diverse extracellular signals and mediate a variety of cellular responses, including mitogenesis, differentiation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f72a679796099a12fc163ca9fa2c6f84
https://doi.org/10.1042/bj3380619
https://doi.org/10.1042/bj3380619
Publikováno v:
Biochemical Society Transactions. 27:164-170
Introduction The amino acid ],-glutamate is the principal excitatory neurotransmitter in the central nervous system. Through its interaction with a broad variety of receptors present at the surface of responding cells, 1.-glutamate has been proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d9b3e857e369438dbe352beb7b863b
https://doi.org/10.1042/bst0270164
https://doi.org/10.1042/bst0270164
Publikováno v:
British Journal of Pharmacology. 126:873-882
1 Different expression levels of the human type Ice metabotropic glutamate (mGlu1 alpha) receptor were obtained in transfected Chinese hamster ovary cells using an isopropyl beta-D-thiogalactopyranoside (IPTG) inducible system. Expression of mGlu1 al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9a11846e2466ac9cdf6cfa3baa4057e
https://doi.org/10.1038/sj.bjp.0702359
https://doi.org/10.1038/sj.bjp.0702359
Publikováno v:
British Journal of Pharmacology. 124:47-54
1. The effects of isoenzyme-selective inhibitors of phosphodiesterases PDE3 and PDE4 on cyclic AMP concentration, two indices of phosphoinositide hydrolysis, and contractile responses to spasmogens have been investigated in bovine tracheal smooth mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2350db48a392c952f6d5624ec3bc93c8
https://doi.org/10.1038/sj.bjp.0701792
https://doi.org/10.1038/sj.bjp.0701792
Publikováno v:
Journal of Lipid Mediators and Cell Signalling. 14:157-168
It is apparent that the phosphoinositide signalling pathway is subject to a variety of regulatory features which will ultimately dictate the magnitude and profile of cellular responses to agonist occupation of PIC-linked receptors. Our understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b355b2f79543e808a8436928798503
https://doi.org/10.1016/0929-7855(96)00521-4
https://doi.org/10.1016/0929-7855(96)00521-4
Publikováno v:
Biochemical Journal. 316:905-913
The effects of protein kinase C (PKC) activation on muscarinic receptor-mediated phosphoinositide and Ca2+ signalling were examined in the human neuroblastoma, SH-SY5Y. Carbachol evoked rapid transient elevations of Ins(1,4,5)P3 and intracellular [Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545edee5654e9d7a4a98de1a8b832c03
https://doi.org/10.1042/bj3160905
https://doi.org/10.1042/bj3160905