Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R. A. H. Adan"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Leptin exerts its effects on energy balance by inhibiting food intake and increasing energy expenditure via leptin receptors in the hypothalamus. While LepR neurons in the arcuate nucleus of the hypothalamus, the primary target of leptin, ha
Externí odkaz:
https://doaj.org/article/8f33abfdc0e242afb1bb2b1d18736e5c
Autor:
R A H, Adan, A A, van Elburg
Publikováno v:
Tijdschrift voor psychiatrie. 64(5)
a id="_idTextAnchor001"/aTranslational (genetic) research focuses on the translation of preclinical research into practice. While many genetic studies have been conducted in recent years, the results do not simply translate to the clinic.brAIM: To vi
Publikováno v:
Molecular psychiatry. 27(2)
Neurological and psychiatric disorders, including substance use disorders, share a range of symptoms, which could be the result of shared genetic background. Many genetic loci have been identified for these disorders using genome-wide association stu
Autor:
Sergueï O. Fetissov, Jochen Seitz, Andreas Karwautz, R. A. H. Adan, A. A. van Elburg, John F. Baines, Beate Herpertz-Dahlmann
Publikováno v:
European psychiatry 64(S1), S0087 (2021). doi:10.1192/j.eurpsy.2021.100 special issue: "Abstracts of the 29th European Congress of Psychiatry"
29. European Congress of Psychiatry, EPA Virtual 2021, online, 2021-04-10-2021-04-13
29. European Congress of Psychiatry, EPA Virtual 2021, online, 2021-04-10-2021-04-13
29. European Congress of Psychiatry, EPA Virtual 2021, online, 10 Apr 2021 - 13 Apr 2021; European psychiatry 64(S1), S0087 (2021). doi:10.1192/j.eurpsy.2021.100 special issue: "Abstracts of the 29th European Congress of Psychiatry"
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Publikováno v:
Obesity reviews : an official journal of the International Association for the Study of Obesity. 19(4)
Western diets, with high consumption of simple sugars and saturated fats, contribute to the rise in the prevalence of obesity. It now seems clear that high-fat diets cause obesity, at least in part, by modifying the composition and function of the mi
Publikováno v:
Physiology & Behavior, 94(5), 689-695. PERGAMON-ELSEVIER SCIENCE LTD
Up to 80% of patients with Anorexia Nervosa (AN) demonstrate hyperactivity. Hyperactivity counteracts weight gain during treatment and is associated with poor outcome of the disease. We hypothesized that hyperactivity in AN patients has a neurobiolog
Autor:
K C G, de Git, R A H, Adan
Publikováno v:
Obesity reviews : an official journal of the International Association for the Study of Obesity. 16(3)
The consumption of Western diets, high in sugar and saturated fat, is a crucial contributor to the alarming incidence of obesity and its associated morbidities. These diets have been reported to induce an inflammatory response in the hypothalamus, wh
Publikováno v:
Current topics in behavioral neurosciences. 6
Hyperactivity in anorexia nervosa is difficult to control and negatively impacts outcome. Hyperactivity is a key driving force to starvation in an animal model named activity-based anorexia (ABA). Recent research has started unraveling what mechanism
Autor:
P H, Jethwa, A, Warner, M J, Fowler, M, Murphy, M W, de Backer, R A H, Adan, P, Barrett, J M, Brameld, F J P, Ebling
Publikováno v:
Journal of neuroendocrinology. 22(6)
Many vertebrates express profound annual cycles of body fattening, although it is not clear whether these represent differential activity of the central pathways known to mediate homeostatic control of food intake and energy expenditure, or whether t
Publikováno v:
Journal of Biological Chemistry. 267:21746-21752
Cyclic adenosine 3',5'-monophosphate (cAMP) has been implicated as an intracellular messenger mediating osmotic regulation of expression of the gene encoding the neuropeptide vasopressin (VP) in the hypothalamus. We have used a heterologous transient