Výsledky vyhledávání - "R. A. Daines"

A modern analogue of western United States summer palaeoclimate at 6000 years before present

Autor: Cary J. Mock, Andrea R. Brunelle-Daines

Publikováno v: The Holocene. 9:541-545

A modern summer-climate analogue of western United States 6 ka palaeoclimate, based on broad-scale patterns from proxy data and general-circulation-model simulations, provides details concerning its sum mer synoptic climatology. August 1955 serves as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25d284f6d17c1e313f381d996bd7588d
https://doi.org/10.1191/095968399668724603

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(E)-3-[[[[6-(2-Carboxyethenyl)-5-[[8-(4-methoxyphenyl)octyl]oxy]-2-pyridinyl]methyl]thio]methyl]benzoic Acid and Related Compounds: High Affinity Leukotriene B4 Receptor Antagonists

Autor: R A, Daines, P A, Chambers, D S, Eggleston, J J, Foley, D E, Griswold, R C, Haltiwanger, D R, Jakas, W D, Kingsbury, L D, Martin, I, Pendrak

Publikováno v: Journal of Medicinal Chemistry. 37:3327-3336

(E)-3-[[[[6-(2-Carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]methyl]thio]methyl]benzoic acid (11, SB 201993) is a novel, potent LTB4 receptor antagonist. Compound 11 arose from a structure-activity study of a series of trisubstituted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b1deca0554311ece95c563c1e51085
https://doi.org/10.1021/jm00046a017

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Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist

Autor: N, Aiyar, R A, Daines, J, Disa, P A, Chambers, C F, Sauermelch, M, Quiniou, N, Khandoudi, B, Gout, S A, Douglas, R N, Willette

Publikováno v: The Journal of pharmacology and experimental therapeutics. 296(3)

Calcitonin gene-related peptide (CGRP), a potent vasodilatory and cardiotonic peptide, has a potential role for CGRP in diverse physiologic and pathophysiologic situations such as congestive heart failure, diabetes, migraine, and neurogenic inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96553d7c76f0a775c09535e373ab6fc8
https://pubmed.ncbi.nlm.nih.gov/11181905

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Retrosynthetic and synthetic chemistry on amphotericin B. Synthesis of C(1)–C(20) and C(21)–C(38) fragments and construction of the 38-membered macrocycle

Autor: N. S. Simpkins, Tushar Kanti Chakraborty, Kyriacos C. Nicolaou, R. A. Daines

Publikováno v: J. Chem. Soc., Chem. Commun.. :413-416

For the first time, amphotericin B (I) has been successfully derivatized and degraded to intermediates that have been converted into compounds (II)[C(1)–C(20) fragment] and (III)[C(21)–C(38) fragment], projected as major key intermediates for a t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f547a22de287e6b283a0980d678b2300
https://doi.org/10.1039/c39860000413

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