Zobrazeno 1 - 10
of 420
pro vyhledávání: '"R. A. Cowan"'
Autor:
R. McTaggart‐Cowan, P. A. Vaillancourt, A. Zadra, S. Chamberland, M. Charron, S. Corvec, J. A. Milbrandt, D. Paquin‐Ricard, A. Patoine, M. Roch, L. Separovic, J. Yang
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 11, Iss 11, Pp 3593-3635 (2019)
Abstract Atmospheric physics is represented in numerical models by parameterizations that use resolved‐scale information to estimate the effects of physical processes on the atmospheric state. Over time, our understanding of these processes improve
Externí odkaz:
https://doaj.org/article/b9a626e470ad417fb0773b181f22d871
Publikováno v:
Crisis. 43:135-141
Abstract. Background: "Committed suicide" is often deemed less acceptable than alternative phrases, but such judgments vary widely across individuals. Aim: We tested whether the endorsement of statements containing "committed suicide" is greater when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0316c1062496da3189bc42c6ba973d42
https://doi.org/10.1027/0227-5910/a000767
https://doi.org/10.1027/0227-5910/a000767
Autor:
L. Magnusson, D. Ackerley, Y. Bouteloup, J.-H. Chen, J. Doyle, P. Earnshaw, Y. C. Kwon, M. Köhler, S. T. K Lang, Y.-J. Lim, M. Matsueda, T. Matsunobu, R. McTaggart-Cowan, A. Reinecke, M. Yamaguchi, L. Zhou
Publikováno v:
Bulletin of the American Meteorological Society.
In the DIMOSIC (DIfferent MOdels, Same Initial Conditions) project, forecasts from different global medium-range forecast models have been created based on the same initial conditions. The dataset consists of 10-day deterministic forecasts from seven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6685d8a62a15011dbc3d1d677182e1b
https://doi.org/10.1175/bams-d-21-0234.1
https://doi.org/10.1175/bams-d-21-0234.1
ObjectivesImplantation of a dorsal column stimulator (DCS) for axial spine and radicular pain is a commonly performed procedure. Despite the benefits of this device to reduce pain and improve quality of life, some patients elect to have the device ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c0f500976c3d3d7436867a874a27a45
https://doi.org/10.1101/2021.11.10.21266180
https://doi.org/10.1101/2021.11.10.21266180
Autor:
Harold B. Brooks, Shuang Luo, Timothy I. Meier, Kwame Frimpong, Timothy B. Durham, Matthew Lee, Kevin Robert Fales, Kenneth Jeff Thrasher, Philip W. Iversen, Robert T. Foreman, Yu-Hua Hui, Charles D. Spencer, Sandaruwan Geeganage, Kenneth D. Roth, Alicia Torrado, Yong Wang, Chong Si, Jefferson R. Mc Cowan, Stefan Jon Thibodeaux, Zhipei Wu, Timothy Alan Shepherd, James Lee Toth, Tao Wang, Yue-Wei Qian, Robert Dean Dally, Njoroge F George, Susan A. Konicek
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
AICARFT is a folate dependent catalytic site within the ATIC gene, part of the purine biosynthetic pathway, a pathway frequently upregulated in cancers. LSN3213128 is a potent (16 nM) anti-folate inhibitor of AICARFT and selective relative to TS, SHM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8239c8bd258656146d4e890853c7f73a
http://link.springer.com/article/10.1038/s41598-018-33453-4
http://link.springer.com/article/10.1038/s41598-018-33453-4
Autor:
Alicia Torrado, Shane Atwell, Timothy B. Durham, Njoroge F George, Timothy I. Meier, Brandon J. Margolis, Stefan Jon Thibodeaux, Yu-Hua Hui, Robert Dean Dally, Kevin Robert Fales, Kenneth Jeff Thrasher, James Lee Toth, Jing Wang, Kwame Frimpong, Susan A. Konicek, Yong Wang, Chong Si, Kenneth D. Roth, Matthew Lee, Zhipei Wu, Jefferson R. Mc Cowan, Timothy Alan Shepherd, Sandaruwan Geeganage, Harold B. Brooks
Publikováno v:
Journal of Medicinal Chemistry. 60:9599-9616
A hallmark of cancer is unbridled proliferation that can result in increased demand for de novo synthesis of purine and pyrimidine bases required for DNA and RNA biosynthesis. These synthetic pathways are frequently upregulated in cancer and involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b243bbece7ad1a8ca057dbf632832ff1
https://doi.org/10.1021/acs.jmedchem.7b01046
https://doi.org/10.1021/acs.jmedchem.7b01046
Autor:
Daniel Nehls, Dwight S Tyndall, R Scott Cowan, Reginald J. Davis, Michael N Bucci, Dennis Oh, Robert J. Jackson
Publikováno v:
Medical Devices (Auckland, N.Z.)
Michael N Bucci,1 Dennis Oh,2 R Scott Cowan,3 Reginald J Davis,4 Robert Jackson,5 Dwight S Tyndall,6 Daniel Nehls7 1Piedmont Spine and Neurosurgical Group, PA, Greenville, SC, USA; 2Baystate Medical Center, Springfield, MA, USA; 3New England Orthoped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093de68764c89fbf35cc97b356fdd75f
https://doi.org/10.2147/mder.s127133
https://doi.org/10.2147/mder.s127133
Autor:
C. Mpamhanga, Justyna Iwaszkiewicz, Frederick W. Muskett, P.J. Coombs, Ming Zhang, B. Saxty, Mai Perroud, R. H. Cowan, Margot Thome, Gareth Hall, R. Baravalle, Rebekka Schairer, L.R. Hale, Carr, Chantal Décaillet
Publikováno v:
Proc Natl Acad Sci U S A
The catalytic activity of the protease MALT1 is required for adaptive immune responses and regulatory T (Treg)-cell development, while dysregulated MALT1 activity can lead to lymphoma. MALT1 activation requires its monoubiquitination on lysine 644 (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f36f1c44b408f49607cb06fd5beea7
https://europepmc.org/articles/PMC7022147/
https://europepmc.org/articles/PMC7022147/
Publikováno v:
Geological Society, London, Special Publications. 392:155-175
Two localities where the inverted metamorphic sole of the Oman Ophiolite are best exposed, Sumeini Window and Wadi Tayyin, have been mapped and sampled in greater detail. In both areas an inverted pressure and temperature profile is exposed beneath t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f399902045c46e4cfdbf0e7aab732643
https://doi.org/10.1144/sp392.8
https://doi.org/10.1144/sp392.8
Publikováno v:
Learning and Individual Differences. 16:337-349
The influences of domain-specific meteorological knowledge and general visual–spatial abilities on the comprehension of simple weather maps were examined in a regression-based study involving a sample of participants with relatively low meteorologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd78cec864fcfd23ac41c096515a9883
https://doi.org/10.1016/j.lindif.2007.01.003
https://doi.org/10.1016/j.lindif.2007.01.003