Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R. A. Conradi"'
Publikováno v:
Revista Espanola de Enfermedades Digestivas, Vol 99, Iss 2, Pp 120-121 (2007)
Externí odkaz:
https://doaj.org/article/dc6061d51fde44188511d5ee4cbc54f2
Publikováno v:
Lipophilicity in Drug Action and Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a46ef27a1bee6678926f46d87bd7da51
https://doi.org/10.1002/9783527614998.ch14
https://doi.org/10.1002/9783527614998.ch14
Publikováno v:
Revista Española de Enfermedades Digestivas v.99 n.2 2007
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde68f43c4cb1371012c743ff2e4cf7b
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082007000200015
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082007000200015
Autor:
D A, Kloosterman, J T, Goodwin, P S, Burton, R A, Conradi, B J, Stockman, T A, Scahill, J R, Blinn
Publikováno v:
Biopolymers. 53(5)
Efficient transport of intact drug (solute) across the intestinal epithelium is typically a requirement for good oral activity. In general, the membrane permeability of a solute is a complex function of its size, lipophilicity, hydrogen bond potentia
Autor:
Z, Zhao, K A, Koeplinger, T, Peterson, R A, Conradi, P S, Burton, A, Suarato, R L, Heinrikson, A G, Tomasselli
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(9)
The mechanism of sulfonamide cleavage of PNU-109112, a potent HIV-1 protease inhibitor, by glutathione-S-transferase (GST) was investigated in the presence of reduced GSH. GST-catalyzed sulfonamide cleavage takes place via the nucleophilic attack of
Publikováno v:
Pharmaceutical research. 10(12)
Publikováno v:
Pharmaceutical research. 9(3)
In order to study the influence of hydrogen bonding in the amide backbone of a peptide on permeability across a cell membrane, a series of tetrapeptide analogues was prepared from D-phenylalanine. The amide nitrogens in the parent oligomer were seque
Publikováno v:
Pharmaceutical research. 7(9)
Human colon adenocarcinoma (Caco-2) cells, when grown on semipermeable filters, spontaneously differentiate in culture to form confluent monolayers which both structurally and functionally resemble the small intestinal epithelium. Because of this pro
Publikováno v:
Journal of Medicinal Chemistry. 22:1000-1002
Alkenylidene bisphenols are prepared by condensation of an appropriate phenol with a haloacetaldehyde, followed by base-induced elimination, or by condensation of the corresponding aryl methyl ether, elimination, and deprotection of the phenol with b
Publikováno v:
Journal of the American Chemical Society. 98(15)