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pro vyhledávání: '"R. A. Burges"'
Autor:
R A, Burges
Publikováno v:
Journal of human hypertension. 5
Amlodipine is a 1,4-dihydropyridine calcium antagonist which, although structurally related to nifedipine, has a number of important distinguishing properties. A high oral bioavailability of amlodipine has been demonstrated in a number of animal spec
Autor:
M, Gwilt, J E, Arrowsmith, K J, Blackburn, R A, Burges, P E, Cross, H W, Dalrymple, A J, Higgins
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(1)
UK-68,798 increased the duration and effective refractory period of cardiac action potentials recorded in vitro from canine ventricular muscle and Purkinje fibers in a concentration dependent manner from 5 nM to 1 microM. The resting membrane potenti
Autor:
R A, Burges
Publikováno v:
Postgraduate medical journal. 67
Amlodipine is a novel dihydropyridine calcium antagonist with distinctive pharmacokinetic and pharmacodynamic properties, including slow onset and long duration of action, with minimal effects on cardiac electrophysiology and myocardial contractility
Autor:
R. A. Burges, D. G. Gardiner, M. Gwilt, A. J. Higgins, K. J. Blackburn, S. F. Campbell, P. E. Cross, J. K. Stubbs
Publikováno v:
Journal Of Cardiovascular Pharmacology. 9:110-119
Publikováno v:
Annals of the New York Academy of Sciences. 522:516-518
Autor:
R. A. Burges, K. J. Blackburn
Publikováno v:
Nature New Biology. 235:249-250
WE have studied the enzyme adenyl cyclase to extend the evidence that β-adrenoreceptors consist of at least two types, β-1 and β-2 (refs. 1-4.) Cyclic 3′,5′-AMP has been shown to be the intracellular mediator of the action of various hormones,
Publikováno v:
Nature. 208:894-894
UROKINASE is a proteolytic enzyme in human urine1. Its ability to activate plasminogen has stimulated interest in its potential clinical use as a thrombolytic agent.
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