Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R. A. Bialecki"'
Autor:
R. A. Bialecki
Publikováno v:
Expert Opinion on Investigational Drugs. 7:653-658
The International Business Communications conference on 'Pulmonary Hypertension: New Understanding for Therapeutic Development' was held in San Diego, CA, USA. Approximately 100 basic scientists and clinicians from academia and industry participated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f017296fd2e2772544dc6aaa608f964d
https://doi.org/10.1517/13543784.7.4.653
https://doi.org/10.1517/13543784.7.4.653
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 11:159-163
Endothelins (ET) have been implicated in the pathogenesis of hypoxia-induced pulmonary hypertension. We evaluated the contribution of protein kinase C (PKC) to the ET-1 response of isolated endothelium-denuded extralobar pulmonary artery (PA) from ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78050da07ef0fd70d567463158c1ece7
https://doi.org/10.1006/pupt.1998.0131
https://doi.org/10.1006/pupt.1998.0131
Autor:
Herbert G. Barthlow, W. L. Rumsey, Wallace W. Murdoch, Richard B. Stow, Michael Mallamaci, R. A. Bialecki, Carol S. Fisher
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 274:L552-L559
Endothelins (ETs) have been implicated in the pathogenesis of hypoxia-induced pulmonary hypertension. We determined whether hypoxic exposure of rats (10% O2-90% N2, 1 atm, 1–48 days) altered contraction to ET in isolated segments of endothelium-den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b48fb3b6aba35ba6240613ac514e9f
https://doi.org/10.1152/ajplung.1998.274.4.l552
https://doi.org/10.1152/ajplung.1998.274.4.l552
Autor:
T. N. Tulenko, R. A. Bialecki
Publikováno v:
American Journal of Physiology-Cell Physiology. 264:C32-C39
The effect of cholesterol enrichment on arterial relaxation was studied by evaluating sodium nitroprusside (SNP)- and endothelium-mediated relaxation of isolated rabbit carotid artery. Arterial segments were perfused in vitro (4 h) with cholesterol-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382a645c175d28fe4776e9d201717c49
https://doi.org/10.1152/ajpcell.1993.264.1.c32
https://doi.org/10.1152/ajpcell.1993.264.1.c32
Autor:
W L, Rumsey, D, Aharony, R A, Bialecki, B M, Abbott, H G, Barthlow, R, Caccese, S, Ghanekar, D, Lengel, M, McCarthy, B, Wenrich, B, Undem, C, Ohnmacht, A, Shenvi, J S, Albert, F, Brown, P R, Bernstein, K, Russell
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(1)
The tachykinins, substance P, neurokinin A, and neurokinin B, have been implicated in many diseases. The present study evaluated the pharmacological properties of a novel tachykinin antagonist ZD6021 [3-cyano-N-((2S)-2-(3,4-dichlorophenyl)-4-[4-[2-(m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ead071d78eeb5f7f2b56a413e03c6ef
https://pubmed.ncbi.nlm.nih.gov/11408556
https://pubmed.ncbi.nlm.nih.gov/11408556
Autor:
H.G. Barthlow, B.M. Abbott, W. L. Rumsey, R.B. Stow, R.G. Caccese, R. A. Bialecki, J. Rumsey, C.S. Fisher
Publikováno v:
Pulmonary pharmacologytherapeutics. 12(5)
Endothelin-1 (ET-1) is a potent vasoconstrictor and comitogen implicated in the pathogenesis of pulmonary hypertension (PH). We evaluated the effects of an ET(A)receptor-selective antagonist, ZD1611, on hypoxia-induced PH in rats.Prophylacticandthera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8ecd8d5ebc8448c9b9ea1d1f2c9a66
https://pubmed.ncbi.nlm.nih.gov/10545286
https://pubmed.ncbi.nlm.nih.gov/10545286
Publikováno v:
Chest. 114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaebc922f25c1153501784f537c77d93
https://pubmed.ncbi.nlm.nih.gov/9676649
https://pubmed.ncbi.nlm.nih.gov/9676649
Publikováno v:
The American journal of physiology. 272(2 Pt 1)
The receptors mediating arterial smooth muscle contraction to endothelins (ET) differ among species and origin of vascular bed. We characterized ET receptors mediating contraction of endothelium-denuded human intralobar pulmonary artery (hIPA) and ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427be1f5519a1ef47ea19cafce056a85
https://pubmed.ncbi.nlm.nih.gov/9124371
https://pubmed.ncbi.nlm.nih.gov/9124371
Autor:
R. A. Bialecki
Publikováno v:
IABEM Symposium on Boundary Integral Methods for Nonlinear Problems ISBN: 9789401064064
At elevated temperatures the impact of the thermal stresses on the mechanical behaviour of structures might be significant. Additionally, the presence of higher temperatures causes that the mechanical material properties change. Temperature field cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eed0506e4a3661c6b895d6a1c71cf6b
https://doi.org/10.1007/978-94-011-5706-3_4
https://doi.org/10.1007/978-94-011-5706-3_4
Autor:
R. A. Bialecki, T. N. Tulenko
Publikováno v:
The American journal of physiology. 257(2 Pt 1)
We studied the effects of cholesterol enrichment on arterial function by evaluating its effects on 45Ca2+ uptake and tension development in the carotid artery of the rabbit. Arterial segments were enriched with cholesterol in vitro, using media conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9381eaec255dd4d840870e6dcc6be070
https://pubmed.ncbi.nlm.nih.gov/2548388
https://pubmed.ncbi.nlm.nih.gov/2548388