Výsledky vyhledávání

Development of a miRNA-based classifier for detection of colorectal cancer molecular subtypes

Autor: Ronja S. Adam, Dennis Poel, Leandro Ferreira Moreno, Joey M. A. Spronck, Tim R. de Back, Arezo Torang, Patricia M. Gomez Barila, Sanne ten Hoorn, Florian Markowetz, Xin Wang, Henk M. W. Verheul, Tineke E. Buffart, Louis Vermeulen

Publikováno v: Molecular Oncology, 16, 2693-2709
Molecular Oncology, 16, 14, pp. 2693-2709
Adam, R S, Poel, D, Ferreira Moreno, L, Spronck, J M A, de Back, T R, Torang, A, Gomez Barila, P M, ten Hoorn, S, Markowetz, F, Wang, X, Verheul, H M W, Buffart, T E & Vermeulen, L 2022, ' Development of a miRNA-based classifier for detection of colorectal cancer molecular subtypes ', Molecular oncology, vol. 16, no. 14, pp. 2693-2709 . https://doi.org/10.1002/1878-0261.13210
Molecular oncology, 16(14), 2693-2709. Elsevier

Funder: New York Stem Cell Foundation; Id: http://dx.doi.org/10.13039/100003194
Previously, colorectal cancer (CRC) has been classified into four distinct molecular subtypes based on transcriptome data. These consensus molecular subtypes (CMSs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0c48418cdee935eae702b5a61b89d8
http://www.scopus.com/inward/record.url?scp=85128936267&partnerID=8YFLogxK

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Long-term Survival Update and Extended RAS Mutational Analysis of the CAIRO2 Trial:Addition of Cetuximab to CAPOX/Bevacizumab in Metastatic Colorectal Cancer

Autor: Sanne ten Hoorn, Linda Mol, Dirkje W. Sommeijer, Lisanne Nijman, Tom van den Bosch, Tim R. de Back, Bauke Ylstra, Erik van Dijk, Carel J.M. van Noesel, Roy J. Reinten, Iris D. Nagtegaal, Miriam Koopman, Cornelis J.A. Punt, Louis Vermeulen

Publikováno v: ten Hoorn, S, Mol, L, Sommeijer, D W, Nijman, L, van den Bosch, T, de Back, T R, Ylstra, B, van Dijk, E, van Noesel, C J M, Reinten, R J, Nagtegaal, I D, Koopman, M, Punt, C J A & Vermeulen, L 2022, ' Long-term Survival Update and Extended RAS Mutational Analysis of the CAIRO2 Trial : Addition of Cetuximab to CAPOX/Bevacizumab in Metastatic Colorectal Cancer ', Clinical Colorectal Cancer . https://doi.org/10.1016/j.clcc.2022.11.006
Clinical colorectal cancer. Elsevier
Clinical Colorectal Cancer, 22, 1, pp. 67-75
Clinical Colorectal Cancer, 22, 67-75
Clinical Colorectal Cancer. Elsevier

Contains fulltext : 290951.pdf (Publisher’s version ) (Open Access) BACKGROUND: Here we present updated survival of the CAIRO2 trial and assessed whether the addition of anti-EGFR to anti-VEGF therapy could still be an effective treatment option fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7572ff40393021d942c81fa5a98366b4
https://research.vumc.nl/en/publications/78222ce6-256a-40ff-a6b0-90cb02d060ad

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Akademický článek

Cardiovascular Health and Related Health Care Use of Moluccan-Dutch Immigrants.

Autor: Tim R de Back, Adee J Bodewes, Lizzy M Brewster, Anton E Kunst

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0138644 (2015)

Studies regularly show a higher incidence, prevalence and mortality of cardiovascular disease among immigrant groups from low-income countries. Despite residing in the Netherlands for over 60 years, the Moluccan-Dutch cardiovascular disease profile a

Externí odkaz: https://doaj.org/article/7903847691e1444495b4b7bd42b20eec

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Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone

Autor: Dirkje W. Sommeijer, Matthew T. Seymour, Lianne Koens, Cornelis J. A. Punt, Sanne ten Hoorn, David Fisher, Tim Maughan, Louis Vermeulen, Faye Elliott, Anne Trinh, Phil Quirke, Susan D. Richman, Jenny F. Seligmann, Tim R. de Back, Richard Adams

Publikováno v: British Journal of Cancer
British journal of cancer, 125(8), 1080-1088. Nature Publishing Group

Background Patient selection for addition of anti-EGFR therapy to chemotherapy for patients with RAS and BRAF wildtype metastatic colorectal cancer can still be optimised. Here we investigate the effect of anti-EGFR therapy on survival in different c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329765bd38bc4fb86b004b51f8c16428
https://eprints.whiterose.ac.uk/176152/6/s41416-021-01477-9.pdf

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Fluid overload due to intravenous fluid therapy for vaso-occlusive crisis in sickle cell disease: incidence and risk factors

Autor: Man Wai Tang, Koen de Heer, Charlotte F. van Tuijn, Harriët Heijboer, Jorn J. Gerritsma, Tim R. de Back, Ajab K. Sayedi, Erfan Nur, Aafke E. Gaartman, Bart J. Biemond

Publikováno v: British Journal of Haematology
British journal of haematology, 194(5), 899-907. Wiley-Blackwell

Summary Intravenous fluid therapy (IV‐FT) is routinely used in the treatment of vaso‐occlusive crises (VOCs), as dehydration possibly promotes and sustains erythrocyte sickling. Patients with sickle cell disease (SCD) are at risk of developing di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9b67ee106f447c4788488dd7e88021
https://pubmed.ncbi.nlm.nih.gov/34263922

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Clinical Value of Consensus Molecular Subtypes in Colorectal Cancer: A Systematic Review and Meta-Analysis

Autor: Dirkje W. Sommeijer, Tim R. de Back, Sanne ten Hoorn, Louis Vermeulen

Publikováno v: ten Hoorn, S, de Back, T R, Sommeijer, D W & Vermeulen, L 2022, ' Clinical Value of Consensus Molecular Subtypes in Colorectal Cancer : A Systematic Review and Meta-Analysis ', Journal of the National Cancer Institute, vol. 114, no. 4, pp. 503-516 . https://doi.org/10.1093/jnci/djab106

Background The consensus molecular subtypes (CMSs) of colorectal cancer (CRC) capture tumor heterogeneity at the gene-expression level. Currently, a restricted number of molecular features are used to guide treatment for CRC. We summarize the evidenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ee7714d7c965425a13f31ee5d45ed3
https://pubmed.ncbi.nlm.nih.gov/34077519

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Autoimmune cytopenias in chronic lymphocytic leukemia: a concise review and treatment recommendations

Autor: Arnon P. Kater, Sanne H. Tonino, Tim R. de Back

Introduction: Chronic lymphocytic leukemia (CLL) is frequently complicated by cytopenias, either due to bone marrow infiltration or autoimmunity, resulting in autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), pure red cell aplasia (P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5e50b346607e54f4b452ad328278db

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The High Output State of Sickle Cell Patients: Associations with Anemia-Related Organ Damage

Autor: Charlotte F.J. van Tuijn, Berto J. Bouma, Tim R. de Back, Erfan Nur, Bart J. Biemond

Publikováno v: Blood. 132:3661-3661

Introduction: As longevity of sickle cell disease (SCD) patients increases, chronic organ damage becomes more prevalent. Tricuspid regurgitation velocity (TRV) ≥2.5 m/sec) has long been considered a reliable indicator of pulmonary hypertension (PH)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcc4bcb6865194bad892f82d4278bedb
https://doi.org/10.1182/blood-2018-99-117501

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Cardiovascular Health and Related Health Care Use of Moluccan-Dutch Immigrants

Autor: Anton E. Kunst, Tim R. de Back, Lizzy M. Brewster, Adee J. Bodewes

Publikováno v: PLoS ONE, 10(9). Public Library of Science
PLoS ONE, Vol 10, Iss 9, p e0138644 (2015)
PLoS ONE

Objective Studies regularly show a higher incidence, prevalence and mortality of cardiovascular disease among immigrant groups from low-income countries. Despite residing in the Netherlands for over 60 years, the Moluccan-Dutch cardiovascular disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e09099b47785034a4518ba6945e6cc
https://pure.amc.nl/en/publications/cardiovascular-health-and-related-health-care-use-of-moluccandutch-immigrants(0299955b-22d7-4428-89ac-0b2a4268b0d2).html

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Conductivity Measurements of Electrochemically Oxidized Langmuir−Blodgett Films of Phthalocyaninato−Polysiloxane

Autor: P. Gattinger, R. Silerova (Back), Dieter Neher, H. Rengel

Publikováno v: The Journal of Physical Chemistry B. 103:6858-6862

The dark electrical conductivity of Langmuir−Blodgett assemblies of phthalocyaninato−polysiloxane (PcPS) has been measured at room temperature as a function of the degree of electrochemical oxidation. The conductivity is observed to increase from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b18d35c54fbb9c246e4c0cf5bc444ff8
https://doi.org/10.1021/jp990897q

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