Acute buspirone abolishes the expression of behavioral dopaminergic supersensitivity in mice

Autor: C.M.T. Queiroz, F.B. Alcântara, A.M.L. Yagüe, T. Bibancos, R. Frussa-Filho

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 35, Iss 2, Pp 237-242 (2002)

Previous studies have shown that rats withdrawn from long-term treatment with dopamine receptor blockers exhibit dopaminergic supersensitivity, which can be behaviorally evaluated by enhanced general activity observed in an open-field. Recently, it h

Externí odkaz: https://doaj.org/article/bcaed97e5b4e42b7a985faa89a0850ee

Postnatal Transplantation of Interneuronal Precursor Cells Decreases Anxiety-Like Behavior in Adult Mice

Autor: M. F. Valente, S. Romariz, M. E. Calcagnotto, L. Ruiz, L. E. Mello, R. Frussa-Filho, B. M. Longo

Publikováno v: Cell Transplantation, Vol 22 (2013)

The GABAergic system is critically involved in the modulation of anxiety levels, and dysfunction of GABAergic neurotransmission appears to be involved in the development of generalized anxiety disorder. Precursor cells from the medial ganglionic emin

Externí odkaz: https://doaj.org/article/f5467d01a4bc439eaf31524c848fcdbc

Mitochondrial calcium, oxidative stress and apoptosis in a neurodegenerative disease model induced by 3-nitropropionic acid

Autor: R. Frussa-Filho, Tatiana R. Rosenstock, A C P Carvalho, Aron Jurkiewicz, Soraya S. Smaili

Publikováno v: Journal of Neurochemistry. 88:1220-1228

Intracellular calcium homeostasis is important for cell survival. However, increase in mitochondrial calcium (Ca2+m) induces opening of permeability transition pore (PTP), mitochondrial dysfunction and apoptosis. Since alterations of intracellular Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09e3509f3b0dcb849f41475dcd728301
https://doi.org/10.1046/j.1471-4159.2003.02250.x

MK-801 blocks the development of behavioral sensitization to the ethanol

Autor: R, Camarini, R, Frussa-Filho, M G, Monteiro, H M, Calil

Publikováno v: Alcoholism, clinical and experimental research. 24(3)

Studies have indicated that MK-801 (a noncompetitive N-methyl-D-aspartate receptor antagonist) participates in the long-term neural changes responsible for sensitization to stimulant drugs. It is known that repeated administration of low doses of eth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc9096e1ac6e78e164b320f7a567d7dc
https://pubmed.ncbi.nlm.nih.gov/10776664

Effect of a submaxillary gland extract on Ehrlich tumor growth in mice

Autor: Leoni Villano Bonamin, P. Weill, R. Frussa-Filho

Publikováno v: Brazilian Journal of Medical and Biological Research, Volume: 32, Issue: 10, Pages: 1205-1209, Published: OCT 1999
Brazilian Journal of Medical and Biological Research, Vol 32, Iss 10, Pp 1205-1209 (1999)

Ablation of host submaxillary glands modifies Ehrlich tumor growth and tumor-infiltrating leukocytes, possibly by modifications in the serum level of growth factors produced by this gland. To extend this research, 7-month-old male EPM-1 mice (N = 30)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5751774e0382089fbec952987d6609
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001000005&lng=en&tlng=en