Histamine inhibits the production of interleukin-12 through interaction with H2 receptors

Autor: L. A. Aarden, A. E. Alewijnse, L. C. M. Boeije, E. de Groot, A. Snijders, T C T M van der Pouw Kraan, R. (Rob) Leurs

Publikováno v: Journal of Clinical Investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
Journal of clinical investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
van der Pouw Kraan, C T M, Snijders, A, Boeije, L C M, Groot, E R, Alewijnse, A E, Leurs, R & Aarden, L A 1998, ' Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. ', Journal of Clinical Investigation, vol. 102, no. 10, pp. 1866-1873 . https://doi.org/10.1172/JCI3692

IL-12 is essential for T helper 1 (Th1) development and inhibits the induction of Th2 responses. Atopic diseases, which are characterized by Th2 responses, are associated with the overproduction of histamine. Here we present evidence that histamine,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6033fac61ec7b992f3e32c9f8a14ebd0
https://hdl.handle.net/1871/21567