Zobrazeno 1 - 10
of 2 124
pro vyhledávání: '"R., Perkins"'
Publikováno v:
Conservation Science and Practice, Vol 6, Iss 9, Pp n/a-n/a (2024)
Abstract Networks of marine protected areas (MPAs) are being increasingly implemented worldwide as conservation management tools. We report here on MPA effectiveness using data from a 17‐year long remotely operated vehicle (ROV) monitoring program
Externí odkaz:
https://doaj.org/article/dea1a51cc7e4463f81a3af37921bd44e
Publikováno v:
Microorganisms, Vol 12, Iss 10, p 2073 (2024)
On-time receipt of pneumococcal vaccines is essential in patients with rheumatoid arthritis (RA) as immunosuppressive medications increase their risk of invasive pneumococcal disease (IPD). However, data regarding the impact of timely administration
Externí odkaz:
https://doaj.org/article/daad9a9a31264dfa966790041edb752b
Autor:
Jack S. Talbot, Dean R. Perkins, Christine M. Tallon, Tony G. Dawkins, Andrew J. M. Douglas, Ryan Beckerleg, Andrew Crofts, Melissa E. Wright, Saajan Davies, Jessica J. Steventon, Kevin Murphy, Rachel N. Lord, Christopher J. A. Pugh, Jon L. Oliver, Rhodri S. Lloyd, Philip N. Ainslie, Ali M. McManus, Mike Stembridge
Publikováno v:
Experimental Physiology, Vol 108, Iss 12, Pp 1500-1515 (2023)
Abstract Global cerebral blood flow (gCBF) and cerebrovascular reactivity to hypercapnia (CVRCO2) are modulated by gonadal hormone activity, while insulin‐like growth factor 1 facilitates exercise‐mediated cerebral angiogenesis in adults. Whether
Externí odkaz:
https://doaj.org/article/20b61a3e79984408bcdf31f2b7030741
Autor:
David Cipolla, Jimin Zhang, Brice Korkmaz, James D. Chalmers, Jessica Basso, Daniel Lasala, Carlos Fernandez, Ariel Teper, Kevin C. Mange, Walter R. Perkins, Eugene J. Sullivan
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Brensocatib is an oral, selective, reversible inhibitor of dipeptidyl peptidase-1 (DPP-1), responsible for activating neutrophil serine proteases (NSPs) including neutrophil elastase (NE), proteinase 3 (PR3), and cathepsin G (CatG
Externí odkaz:
https://doaj.org/article/85f654da54af4f9a8406df384ca1cca2
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Temperate rocky reefs are complex habitats that support high levels of biodiversity and productivity. However, the sessile benthic communities attached to these reefs are vulnerable to climate change and local human impacts due to their limited capac
Externí odkaz:
https://doaj.org/article/6470b3d5115047bd811f8d3c577d3baf
Autor:
Manuel Corpas, Carmen de Mendoza, Víctor Moreno-Torres, Ilduara Pintos, Pedro Seoane, James R. Perkins, Juan A.G. Ranea, Segun Fatumo, Tamas Korcsmaros, José Manuel Martín-Villa, Pablo Barreiro, Octavio Corral, Vicente Soriano
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107735- (2023)
Summary: Characterization of host genetic factors contributing to COVID-19 severity promises advances on drug discovery to fight the disease. Most genetic analyses to date have identified genome-wide significant associations involving loss-of-functio
Externí odkaz:
https://doaj.org/article/2b5a8dac1ff64d15bb041f095ac7cbc1
Autor:
Madeline E. Sherlock, Gadareth Higgs, Diane Yu, Danielle L. Widner, Neil A. White, Narasimhan Sudarsan, Harini Sadeeshkumar, Kevin R. Perkins, Gayan Mirihana Arachchilage, Sarah N. Malkowski, Christopher G. King, Kimberly A. Harris, Glenn Gaffield, Ruben M. Atilho, Ronald R. Breaker
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1059-1076 (2022)
Riboswitch architectures that involve the binding of a single ligand to a single RNA aptamer domain result in ordinary dose-response curves that require approximately a 100-fold change in ligand concentration to cover nearly the full dynamic range fo
Externí odkaz:
https://doaj.org/article/d97719da4d29432b890e0c781466c70c
Autor:
Patrick P. McDonald, Franziska Graf Leifer, Jessica Basso, Dan Lasala, Dedong Li, Kuan-Ju Chen, Jimin Zhang, Walter R. Perkins, David C. Cipolla
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Rheumatoid arthritis (RA) is a painful and incurable disease characterized by chronic joint inflammation and a progressive destruction of cartilage and bone. Although current treatments have improved clinical outcomes for some patients, the high rela
Externí odkaz:
https://doaj.org/article/8bdd637f3aad40d9abb74d1bb722c196
Autor:
Kuan-Ju Chen, Jimin Zhang, Daniel LaSala, Jessica Basso, Donald Chun, Yuchen Zhou, Patrick P. McDonald, Walter R. Perkins, David C. Cipolla
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neutrophils have been implicated in initiating and perpetuating systemic lupus erythematosus and the resultant kidney damage in lupus nephritis (LN) patients, in part through an excessive release of neutrophil serine proteases (NSPs). NSP zymogens ar
Externí odkaz:
https://doaj.org/article/39068ea155094654afda96d63a8b6583
Autor:
Adrian R. Muxworthy, Jack N. Turney, Liang Qi, Evelyn B. Baker, Joseph R. Perkins, Maryam A. Abdulkarim
Publikováno v:
Frontiers in Earth Science, Vol 11 (2023)
High-temperature susceptibility (HT-χ) data are routinely measured in Earth, planetary, and environmental sciences to rapidly identify the magnetic mineralogy of natural systems. The interpretation of such data can be complicated. Whilst some minera
Externí odkaz:
https://doaj.org/article/16164c9a4fa249b98bba24688b4fe311