Zobrazeno 1 - 10
of 301
pro vyhledávání: '"R., Neuwirtová"'
Publikováno v:
Mitochondrion. 4:321-329
It was hypothesised that mitochondrial iron overload in patients with refractory anemia with ring sideroblasts (RARS) results from mitochondrial DNA (mtDNA) mutations. To analyse the mtDNA sequence of iron storing mitochondria sensitively, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e4995bc15bea34075cbe96393b3a83
https://doi.org/10.1016/j.mito.2004.06.002
https://doi.org/10.1016/j.mito.2004.06.002
Publikováno v:
Vnitrni lekarstvi. 59(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37993c488f98dfc8f3d3983ada5d342e
https://pubmed.ncbi.nlm.nih.gov/23909270
https://pubmed.ncbi.nlm.nih.gov/23909270
Publikováno v:
Casopis lekaru ceskych. 147(12)
The prognosis of multiple myeloma (MM) has substantially improved during last decades due to new, so-called targeted drugs--proteasome inhibitor bortezomib and immunomodulatory drugs (ImiDs), thalidomide and lenalidomide. They could be used in variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1600070f1370e14237a5ea994544825
https://pubmed.ncbi.nlm.nih.gov/19235487
https://pubmed.ncbi.nlm.nih.gov/19235487
Publikováno v:
Vnitrni lekarstvi. 53(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::316b877befa0825458d1f4e76d042771
https://pubmed.ncbi.nlm.nih.gov/17419182
https://pubmed.ncbi.nlm.nih.gov/17419182
Publikováno v:
Casopis lekaru ceskych. 145(8)
Successful therapy with ATG and cyclosporine A in some myelodysplastic syndrome (MDS) patients led us to study the existence of T cells attacking autologous hemopoietic cells. In our study, we attempted to give the direct prove of autoreactive T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aac1dc94e83f699b2ce18d9187b93ce7
https://pubmed.ncbi.nlm.nih.gov/16995421
https://pubmed.ncbi.nlm.nih.gov/16995421
Autor:
O, Fuchs, R, Neuwirtová
Publikováno v:
Vnitrni lekarstvi. 52(6)
Posttranslational protein modifications are effective devices that cells use to control the functions of proteins. Ubiquitin-like protein modifiers (Ubls) are posttranslationally attached to proteins by enzymatic reactions that are similar to ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7356254aafc6c7a01d3fa21edbe1e10a
https://pubmed.ncbi.nlm.nih.gov/16871767
https://pubmed.ncbi.nlm.nih.gov/16871767
Autor:
O, Fuchs, R, Neuwirtová
Publikováno v:
Vnitrni lekarstvi. 52(4)
Proteasome is protein complex with proteolytic activity. Proteasomes are in addition to lysosomes the main proteolytic machinery of the eukaryotic cell. Proteins destined for degradation in proteasomes are marked by ubiquitinylation, which consists i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52b27320193ab0c5256c1cadca3a381d
https://pubmed.ncbi.nlm.nih.gov/16755993
https://pubmed.ncbi.nlm.nih.gov/16755993
Publikováno v:
Casopis lekaru ceskych. 140(24)
Single cell gel electrophoresis or comet assay is used at present in the world to study of DNA damage, DNA repair and apoptosis. The aim of the work is to introduce the principle of comet assay to the medical community and to give a basic survey of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9e0a3e7dcf6c2f229109bbe7fa7fce9
https://pubmed.ncbi.nlm.nih.gov/14655279
https://pubmed.ncbi.nlm.nih.gov/14655279
Publikováno v:
Sbornik lekarsky. 103(3)
A number of prognostic scoring systems for patients with myelodysplastic syndrome (MDS) have been introduced since FAB classification of the MDS in 1982. Recently, the International Prognostic Scoring System (IPSS), published in 1997 by Greenberg et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e5e1d823809c7f02603348f7ebd295d
https://pubmed.ncbi.nlm.nih.gov/12688177
https://pubmed.ncbi.nlm.nih.gov/12688177
Publikováno v:
Sbornik lekarsky. 103(3)
Myelodysplastic syndromes (MDS) are classified as oncohematologic, clonal diseases. However, some MDS subtypes lack malignant clinical features. Literary data on the clonality of blood cells in MDS are controversial. Therefore we examined the clonali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20114b906224454d2e525db022728426
https://pubmed.ncbi.nlm.nih.gov/12688178
https://pubmed.ncbi.nlm.nih.gov/12688178