Zobrazeno 1 - 10
of 374
pro vyhledávání: '"R Zucali"'
Publikováno v:
European Journal of Haematology. 57:149-156
The presence of bcl-2 in myeloid leukemias has been associated with a decrease in therapy-induced apoptosis, reduced patient survival and in vitro autonomous growth of leukemic cells. The present study focuses on the quantitation of resistance to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc817cc1e3bb498df5a37b164a902ad
https://doi.org/10.1111/j.1600-0609.1996.tb01353.x
https://doi.org/10.1111/j.1600-0609.1996.tb01353.x
Publikováno v:
Cytometry Part B: Clinical Cytometry. :281-289
Background: We have been interested in studying the roles of two aldehyde dehydrogenases in the biology of lung cancer. In this study, we seek to apply Aldefluor flow cytometry-based assay for the measurement of aldehyde dehydrogenase (ALDH) activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf28700ca98f888005b1e4a97d74475b
https://doi.org/10.1002/cyto.b.20161
https://doi.org/10.1002/cyto.b.20161
Autor:
James R. Zucali, Sonia Levi, Patrick Gentile, Keisuke Miyazawa, Thomas A. Rado, Paolo Arosio, Carolyn H. Srivastava, Charlie Mantel, Hal E. Broxmeyer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1c95ad229ca2d7f00905a5115e4e0a
https://doi.org/10.1159/000419358
https://doi.org/10.1159/000419358
Publikováno v:
Cancer Chemotherapy and Pharmacology. 59:127-136
Purpose: Aldehyde dehydrogenases class-1A1 (ALDH1A1) and class-3A1 (ALDH3A1) have been associated with resistance to cyclophosphamide (CP) and its derivatives. We have previously reported the downregulation of these enzymes by all-trans retinoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d72e7c06d395739570908003823401
https://doi.org/10.1007/s00280-006-0233-6
https://doi.org/10.1007/s00280-006-0233-6
Autor:
Santosh Gowda, James R. Zucali, Govind R. Vartikar, Dagmara Mohuczy, Jan S. Moreb, Amir A Gabr
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 312:339-345
Multiple prior studies have identified aldehyde dehydrogenases (ALDH) that are capable of oxidizing retinal to retinoic acid. In this study, we test the hypothesis that the accumulation of intracellular retinoic acid may lead to the suppression of AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af79ad6f180c0529b6bbb3b6f45738f7
https://doi.org/10.1124/jpet.104.072496
https://doi.org/10.1124/jpet.104.072496
Autor:
David N. Silverman, James R. Zucali, Amy S. Hearn, Anupam Agarwal, Harry S. Nick, Jorge E. Garcia, Vincent Leveque, Bradley S. Fletcher, Christopher A. Davis, J. Andres Melendez, Justin S. Bickford
Publikováno v:
Journal of Biological Chemistry. 279:12769-12776
Mn-SOD serves as the primary cellular defense against oxidative damage by converting superoxide radicals () to O2 and H2O2. A unique characteristic of this mitochondrial anti-oxidant enzyme is the conservation from bacteria to man of a rapidly formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef520191db002e77d3640c52773d24c2
https://doi.org/10.1074/jbc.m310623200
https://doi.org/10.1074/jbc.m310623200
Publikováno v:
British Journal of Haematology. 120:457-463
Overexpression of manganese superoxide dismutase (MnSOD) has been postulated as one possible mechanism of protection from oxidative damage and free radicals. Doxorubicin treatment induces oxygen free radicals, leading to cytotoxicity and myelosuppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c93da6e3aba790d79913191f023cdc6
https://doi.org/10.1046/j.1365-2141.2003.04074.x
https://doi.org/10.1046/j.1365-2141.2003.04074.x
Publikováno v:
Blood. 93:3558-3564
Transfusions (Tx) of Ultraviolet B (UVB)-irradiated peripheral blood mononuclear leukocytes (MNL) have been shown to induce humoral immune tolerance to major histocompatability complex (MHC) antigens (Blood 88:4375, 1996). To determine whether cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fddf9d0b289263642228bbd7054b79bd
https://doi.org/10.1182/blood.v93.10.3558.410k31_3558_3564
https://doi.org/10.1182/blood.v93.10.3558.410k31_3558_3564
Autor:
B Salvadori, F. Cusumano, S. Andreola, Rosalba Miceli, R. Zucali, Umberto Veronesi, A. R. Conti, Ettore Marubini
Publikováno v:
British Journal of Surgery. 86:84-87
Background This study aimed to analyse the possibility of surgical rescue of intrabreast tumour recurrence (IBTR) following conservative operation for breast cancer, i.e. quadrantectomy, axillary dissection and radiotherapy. Methods Of 2544 patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2907a323f4fe6c15c119777165b634b
https://doi.org/10.1046/j.1365-2168.1999.00961.x
https://doi.org/10.1046/j.1365-2168.1999.00961.x