Zobrazeno 1 - 10
of 40
pro vyhledávání: '"R William DePaolo"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118875 (2015)
The contribution of vitamin A to immune health has been well established. However, recent evidence indicates that its active metabolite, retinoic acid (RA), has the ability to promote both tolerogenic and inflammatory responses. While the outcome of
Externí odkaz:
https://doaj.org/article/5f206cbf317c4c84ac8b27e9a780424b
Autor:
Marion Avril, R. William DePaolo
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Colorectal cancer (CRC) is a significant public health problem accounting for about 10% of all new cancer cases globally. Though genetic and epigenetic factors influence CRC, the gut microbiota acts as a significant component of the disease’s etiol
Externí odkaz:
https://doaj.org/article/95f5a46bcdc74c50b8749fa29f0a7f4c
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver injury and liver transplantation in Western countries. The pathogenesis of NAFLD includes overnutrition-associated metabolic syndrome or the improper consumption of dietar
Externí odkaz:
https://doaj.org/article/2e0515240f904fff804e2bcd7bad6a42
Proportion of genus-level bacteria affected by the interaction of housing and genotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8623b9524d30acfb57e2177e9f224d5a
https://doi.org/10.1158/1940-6207.22533770.v1
https://doi.org/10.1158/1940-6207.22533770.v1
Autor:
Heinz-Josef Lenz, R. William DePaolo, Volker Heinemann, Alfredo Falcone, Chiara Cremolini, Marta Schirripa, Mitsukuni Suenaga, Yuji Miyamoto, Jordan D. West, Anish Parekh, Martin D. Berger, Satoshi Matsusaka, Stefan Stremitzer, Yu Sunakawa, Yan Ning, Dongyun Yang, Wu Zhang, Shu Cao, Sebastian Stintzing, Fotios Loupakis, Satoshi Okazaki
This figure shows the signal pathway of TLR1, TLR2, and TLR6. TLR1 and TLR6, each of which forms a heterodimer with TLR2, initiate MAPK or NFκB pathway through TAK1. MyD88: myeloid differentiation factor88, TRAF: TNF receptor-associated factor, IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d381791c040b61920f12222919b865
https://doi.org/10.1158/1535-7163.22508994
https://doi.org/10.1158/1535-7163.22508994
Autor:
Heinz-Josef Lenz, R. William DePaolo, Volker Heinemann, Alfredo Falcone, Chiara Cremolini, Marta Schirripa, Mitsukuni Suenaga, Yuji Miyamoto, Jordan D. West, Anish Parekh, Martin D. Berger, Satoshi Matsusaka, Stefan Stremitzer, Yu Sunakawa, Yan Ning, Dongyun Yang, Wu Zhang, Shu Cao, Sebastian Stintzing, Fotios Loupakis, Satoshi Okazaki
This table shows the association of each SNP and clinical outcome in TRIBE. The association between SNP and clinical outcome in FIRE-3 is also demonstrated when there are statistically significant associations in TRIBE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65077c3c10f653ebfe2f94ffa87f5cfd
https://doi.org/10.1158/1535-7163.22508991
https://doi.org/10.1158/1535-7163.22508991
Publikováno v:
Cancer Prevention Research. 13:25-40
Tightly regulated immune responses must occur in the intestine to avoid unwanted inflammation, which may cause chronic sequela leading to diseases such as colorectal cancer. Toll-like receptors play an important role in preventing aberrant immune res
Food-borne illnesses are a major health concern worldwide. While 1 in 6 individuals are infected in the United States yearly, there is little research into which dietary factors can alter the risk of infection. Despite evidence suggesting a correlati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::328d6b890bc6c4dc44accdb2454173b6
https://doi.org/10.1101/2021.12.06.471175
https://doi.org/10.1101/2021.12.06.471175
Publikováno v:
Current Protocols. 1
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) provides a fast and easy means to identify culturable microorganisms to the species level. The sample preparation of microbial colonies for MALDI-TOF analysis
Autor:
Denise Chac, Ian B. Stanaway, C Diener, Mariion Avril, Wynn Burke, Jennifer Z. Huang, P. McCleary, Amy D. Willis, Sumita Jain, Benjamin D. Ross, Melissa C. Kordahi, William M. Grady, Sean M. Gibbons, R. William DePaolo, Vince Friedman, Richard P. Darveau, Cynthia W. Ko, Anika Parker
Publikováno v:
SSRN Electronic Journal.
The rising incidence of colorectal cancer (CRC) is a major health concern worldwide, yet little is known about the composition and role of the microbiota associated with precancerous polyps. Here, we found distinct microbial signatures between patien