Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R Whidborne"'
Autor:
Annette Fink, Dianne De Santis, Manuela Testi, Marcel G.J. Tilanus, Blanka Vidan-Jeras, Thuong Hien Tran, Gottfried Fischer, Mathijs Groeneweg, Ingrid Fae, Marco Andreani, Ben M. Matern, Christina E.M. Voorter, R. Whidborne, Sendi Montanic
Publikováno v:
Human Immunology. 79(11):763-772
The gold standard for typing at the allele level of the highly polymorphic Human Leucocyte Antigen (HLA) gene system is sequence based typing. Since sequencing strategies have mainly focused on identification of the peptide binding groove, full-lengt
Autor:
David Groth, R Whidborne, J.D. Wetherall, Christine Bundell, Patricia Martinez, Audrey A. Margery-Muir
Publikováno v:
Lupus. 27:1687-1696
The relationship between serum concentration of complement C4 ([C4]) and C4 gene copy number (GCN) was investigated in 56 systemic lupus erythematosus (SLE) patients and 33 age and sex-matched controls in a Western Australian population. C4A and C4B
Supplemental material for Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort by A A Margery-Muir, C Bundell, J D Wetherall, R Whidborn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13afa4fa0de3a281d018403322eeb505
Autor:
Meilyn Hew, Alison Castley, Campbell S. Witt, Patricia Martinez, Dominic F. J. Mallon, J.D. Wetherall, Audrey A. Margery-Muir, R. Whidborne
Publikováno v:
Arthritis & Rheumatology. 66:2512-2520
Objective To establish gene copy number (GCN)–specific normal ranges for serum C4 genes and to determine their utility with respect to the interpretation of chronically low serum C4 concentrations in patients with clinically quiescent systemic lupu
Autor:
R. Whidborne, F. Trimboli, David Sayer, Campbell S. Witt, Frank T. Christiansen, Brian Brestovac
Publikováno v:
Tissue Antigens. 57:46-54
The HLA-DRB1 sequencing based typing strategies reported to date require separate amplifications of each sample with a series of group-specific primers followed by sequencing of any resulting polymerase chain reaction (PCR) products. Whilst this resu
Publikováno v:
Scandinavian Journal of Rheumatology. 44:255-256
Tumour necrosis factor receptor-associated periodic syndrome (TRAPS; MIM no. 142680) is the most common autosomal dominant autoinflammatory disorder caused by heterozygous mutations in the TNFRSF1A...
Autor:
Andrew Lucas, David Burgner, J Waring, Pam Nicol, R. Whidborne, Elizabeth McKinnon, Aesen Thambiran, Michaela Lucas, Martyn A. French
Publikováno v:
Thorax. 65(5)
BACKGROUND Diagnosis of latent tuberculosis infection (LTBI) is a cornerstone of the health assessment of resettled high incidence populations, particularly in children. Two blood-based interferon gamma release assays (IGRAs), T-SPOT.TB and QFT-Gold
Autor:
Dianne De Santis, Marcel G. J. Tilanus, Frank T. Christiansen, E. Rozemuller, D.C. Sayer, R. Whidborne
Publikováno v:
Tissue antigens. 63(5)
We have described previously a novel single-tube polymerase chain reaction (PCR) amplification (STAmp) protocol for the efficient sequencing-based typing (SBT) of human leukocyte antigen (HLA)-DRB1. The PCR amplification mix includes primers to each
Publikováno v:
Tissue antigens. 57(1)
The HLA-DRB1 sequencing based typing strategies reported to date require separate amplifications of each sample with a series of group-specific primers followed by sequencing of any resulting polymerase chain reaction (PCR) products. Whilst this resu
Publikováno v:
Tissue Antigens. 69:56-57
The Royal Perth Hospital laboratory has been using sequencing-based typing for all HLA loci since 2002. In the period to October 2005, approximately 12,000 HLA A and HLA B, 5000 HLA C and DQB1, and 17,000 DRB1 requests have been processed. Twenty nin