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pro vyhledávání: '"R W Van Dyke"'
Autor:
R W Van Dyke
Publikováno v:
American Journal of Physiology-Cell Physiology. 272:C1123-C1133
Acidification of endocytic vesicles, driven by the vacuolar H+ pump, is affected by parallel ion transporters. Because adenosine 3',5'-cyclic monophosphate (cAMP) and heterotrimeric G proteins may alter ion transporters, I tested whether cholera and
Autor:
R. W. Van Dyke
Publikováno v:
American Journal of Physiology-Cell Physiology. 269:C943-C954
Endocytic vesicles are acidified by an electrogenic vacuolar H(+)-ATPase. These studies examined whether rat liver endosomes also exhibit Na+/H+ exchange and whether this transporter alters acidification. Extravesicular Na+ caused saturable proton ef
Autor:
Tom Grotmol, R. W. Van Dyke
Publikováno v:
Digestive Diseases and Sciences. 37:1709-1717
The aim of the present study was to examine the possible role of microtubules in chloride secretion by distal rat colon stimulated by prostaglandin (PGE2) and theophylline. Distal colonic tissue from male rats was mounted in Ussing chambers, and shor
Publikováno v:
Journal of Biological Chemistry. 267:15412-15418
Glutamate, the major excitatory neurotransmitter in the mammalian central nervous system, is transported into bovine synaptic vesicles in a manner that is ATP dependent and requires a vesicular electrochemical proton gradient. We studied the electric
Autor:
R W Van Dyke
Publikováno v:
Hepatology. 14:201-204
We have used retrovirus-mediated gene transfer to demonstrate complementation of the cystic fibrosis (CF) defect in vitro. Amphotropic retroviruses were used to transduce a functional cystic fibrosis transmembrane conductance regulator (CFTR) cDNA in
Autor:
R. W. Van Dyke, J. C. Boucher, Vojo Deretic, Jennifer M. Skidmore, L E Tatterson, Jens F. Poschet
The CFTR gene encodes a transmembrane conductance regulator, which is dysfunctional in patients with cystic fibrosis (CF). The mechanism by which defective CFTR (CF transmembrane conductance regulator) leads to undersialylation of plasma membrane gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccad888ed116cf759ee5cc969d6dce2d
https://europepmc.org/articles/PMC61151/
https://europepmc.org/articles/PMC61151/
Autor:
R W, Van Dyke
Publikováno v:
Hepatology (Baltimore, Md.). 32(6)
In prior studies, we showed that cholera (CTX) and pertussis toxins (PTX) increase rat liver endosome acidification. This study was performed to characterize the effects of these toxins and cyclic adenosine monophosphate (cAMP) on endosome ion transp
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
Hepatic organic cation transport consists, in part, of carrier-mediated sinusoidal uptake stimulated by an inside-negative membrane potential and canalicular excretion driven by electroneutral organic cation/H+ exchange. Intracellular organic cation
Autor:
R W Van Dyke
Publikováno v:
Subcellular Biochemistry ISBN: 9781461376743
In eukaryotic cells the interior space of endosomes, lysosomes, and a variety of other intracellular organelles is maintained at a pH considerably more acidic than either cytosolic pH or extracellular pH. This acidic vesicle interior can be demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc5bbb6580b65212e220ef847d45e2d8
https://doi.org/10.1007/978-1-4615-5833-0_10
https://doi.org/10.1007/978-1-4615-5833-0_10
Autor:
R W, Van Dyke
Publikováno v:
Sub-cellular biochemistry. 27
Lysosomes, endosomes, and a variety of other intracellular organelles are acidified by a family of unique proton pumps, termed the vacuolar H(+)-ATPases, that are evolutionarily related to bacterial membrane proton pumps and the F1-F0 H(+)-ATPases th