Výsledky vyhledávání - "R W Rosenstein"

Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. I. Mapping of genes for Id-460 expression to the variable region of immunoglobulin heavy-chain locus and to the variable region of immunoglobulin kappa-light-chain locus

Autor: Charles A. Janeway, R W Rosenstein, P D Gottlieb, E A Dzierzak

Publikováno v: The Journal of Experimental Medicine

The genetic contro of the expression of an idiotype (Id-460) associated with the 2,4-dinitrophenyl (DNP)-binding BALB/c myeloma protein MOPC 460 was studied using congenic strains of mice. It was shown that the expression of high levels of Id-460 dur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4a2225666144a7bee46d4be2ecf021
https://doi.org/10.1084/jem.152.3.720

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Characterization of T-cell surface proteins bound by heterologous antisera to antigen-specific T-cell products

Autor: R W Rosenstein, Wlodzimierz Ptak, Robert E. Cone, J H Murray, G M Iverson, Richard K. Gershon

Publikováno v: Proceedings of the National Academy of Sciences. 78:6411-6415

Heterologous antisera specific for murine T-cell antigen-recognition molecules were prepared by immunization of rabbits with dinitrophenyl-specific murine T-cell suppressor factors that had been purified by hapten-affinity chromatography. The antiser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c1f0b54429018eea2ab1d5229ebc1b
https://doi.org/10.1073/pnas.78.10.6411

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Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. II. Transient idiotypic dominance

Autor: E A Dzierzak, R W Rosenstein, Charles A. Janeway

Publikováno v: The Journal of Experimental Medicine

After immunization of mice with 2,4-dinitrophenyl-ovalbumin (DNP-OVA), it was shown previously that strains having Igh-Va genes and able to express light chains of the Vk1 group produce high levels of anti-DNP antibody bearing an idiotype (Id-460) as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdd99753ef4d5a6d275940e73921f62
https://doi.org/10.1084/jem.154.5.1432

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Purification and characterization of TNP-specific immunoregulatory molecules produced by T cells sensitized by picrylchloride (PC1F)

Autor: W Ptak, R K Gershon, R W Rosenstein, J H Murray, R E Cone

Publikováno v: The Journal of Immunology. 131:2859-2863

T cell-derived TNP-specific factors associated with immunoregulatory activity were obtained by culture of T cells obtained from mice sensitized by skin-painting with picrylchloride. Culture medium was absorbed to TNP-Sepharose and TNP binding protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fc3796bec1f40e1eb527b5af4503acf
https://doi.org/10.4049/jimmunol.131.6.2859

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Transfer of an antigen-specific immediate hypersensitivity-like reaction with an antigen-binding factor produced by T cells

Autor: Wlodzimierz Ptak, R W Rosenstein, Philip W. Askenase, Richard K. Gershon

Publikováno v: Proceedings of the National Academy of Sciences. 79:1969-1973

The fact that T cell-dependent activation of mast cells occurs in delayed-type hypersensitivity led us to investigate whether a T cell product could mimic some of the functions of IgE. We report that 24- or 48-hr cultures of T cells from mice immuniz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554763a8c7eee80fee78f8c2d6384dd6
https://doi.org/10.1073/pnas.79.6.1969

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Interactions between molecules (subfactors) released by different T cell sets that yield a complete factor with biological (suppressive) activity

Autor: Richard K. Gershon, Wlodzimierz Ptak, R W Rosenstein

Publikováno v: Proceedings of the National Academy of Sciences. 79:2375-2378

T cells that have been immunized to express optimal levels of contact hypersensitivity upon adoptive transfer to normal animals can be inhibited from doing so by incubating them with an antigen-specific T suppressor factor. This factor is composed of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4186e4e79b15e51e6d070114bbfe4319
https://doi.org/10.1073/pnas.79.7.2375

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T cells produce an antigen-binding factor with in vivo activity analogous to IgE antibody

Autor: R W Rosenstein, Wlodzimierz Ptak, Philip W. Askenase

Publikováno v: The Journal of Experimental Medicine

T cell-dependent activation of resident tissue mast cells is required for the elicitation of delayed-type hypersensitivity skin reactions in mice. A T cell-derived antigen-binding factor that transfers the ability to elicit an immediate hypersensitiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2f48054180d3eac2fa12f0346ea20e
http://europepmc.org/articles/PMC2186957

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Isolation and partial characterization of an antigen-specific T-cell factor associated with the suppression of delayed type hypersensitivity

Autor: R W Rosenstein, Robert E. Cone, Wlodzimierz Ptak, G M Iverson, J H Murray, Richard K. Gershon

Antigen-specific factors associated with immunosuppressive activity, released by cultured T cells from mice tolerant to the haptens trinitrophenyl, dinitrophenyl and oxazolone, were purified by hapten affinity chromatography. Their binding specificit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3e3967d0763ff827b3eb8df2f0daa1
https://europepmc.org/articles/PMC348874/

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