Zobrazeno 1 - 5
of 5
pro vyhledávání: '"R W Knippenberg"'
Publikováno v:
Journal of Leukocyte Biology. 52:407-414
We have previously demonstrated that bactericidal activity and superoxide anion (O2-) production are depressed concomitantly in polymorphonuclear leukocytes (PMNs) following thermal injury in a guinea pig model, and the bactericidal defect is related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96acc1da68ad50997f8c8801c65bcd6d
https://doi.org/10.1002/jlb.52.4.407
https://doi.org/10.1002/jlb.52.4.407
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(2)
MDL 105,212 has been identified as a potent, nonpeptide NK-1 and NK-2 receptor antagonist that inhibits effects of substance P and neurokinin A in vitro and in vivo (Kudlacz et al., 1996). In the present study, the compound inhibited capsaicin-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af06d80b126af31512db42a92e8dc93a
https://pubmed.ncbi.nlm.nih.gov/8930178
https://pubmed.ncbi.nlm.nih.gov/8930178
Autor:
E M, Kudlacz, S A, Shatzer, R W, Knippenberg, D E, Logan, M, Poirot, P L, van Giersbergen, T P, Burkholder
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(2)
We have identified and characterized a novel, potent, nonselective tachykinin receptor antagonist, MDL 105,212A [(R)-1-[2-[3-(3,4- dichlorophenyl)-1-(3,4,5-trimethoxybenzoyl)-pyrrolidin-3-yl] -ethyl]- 4-phenylpiperidine-4-carboxamide, hydrochloride].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7267b5a146c9c2c6021867a8cd9e772
https://pubmed.ncbi.nlm.nih.gov/8627566
https://pubmed.ncbi.nlm.nih.gov/8627566
Publikováno v:
The Journal of Immunology. 143:2609-2616
PG of the E series inhibit major effector functions of polymorphonuclear leukocytes (PMN) by elevating intracellular cAMP. The present study investigated the involvement of this mechanism in the bactericidal defect of PMN induced by thermal injury in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91d6df5ccf19ad3dcdbc6d747b35e67b
https://doi.org/10.4049/jimmunol.143.8.2609
https://doi.org/10.4049/jimmunol.143.8.2609
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 143(8)
PG of the E series inhibit major effector functions of polymorphonuclear leukocytes (PMN) by elevating intracellular cAMP. The present study investigated the involvement of this mechanism in the bactericidal defect of PMN induced by thermal injury in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8303dfcd6933b97b1670adfc703f450
https://pubmed.ncbi.nlm.nih.gov/2551963
https://pubmed.ncbi.nlm.nih.gov/2551963