Zobrazeno 1 - 10
of 40
pro vyhledávání: '"R W Holz"'
Publikováno v:
Molecular and Cellular Biology. 15:1137-1143
Rab3A is a small, Ras-like GTPase expressed in neuroendocrine cells, in which it is associated with secretory vesicle membranes and regulates exocytosis. Using the yeast two-hybrid system, we have identified a rat brain cDNA encoding a novel 50-kDa p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bf0632efc9336feae6a3dc5847656a
https://doi.org/10.1128/mcb.15.3.1137
https://doi.org/10.1128/mcb.15.3.1137
Publikováno v:
Journal of Biological Chemistry. 269:17215-17220
Secretion of catecholamines from individual bovine adrenal medullary cells in culture was examined by amperometry with 1-micron radius carbon-fiber electrodes. Vesicular secretion is observed as a series of current spikes upon exposure to a secretago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1e56b11a03a720f6cc254f3a83483e
https://doi.org/10.1016/s0021-9258(17)32542-5
https://doi.org/10.1016/s0021-9258(17)32542-5
Autor:
R W, Holz, D, Axelrod
Publikováno v:
Acta physiologica (Oxford, England). 192(2)
Our current notions of different granule pools, granule interaction with the plasma membrane, and ultimately granule and plasma membrane soluble N-ethylmaleimide-sensitive-factor attachment protein (SNARE) interactions, result largely from inferences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b55d969865d9da2e9a844fbd7e7f8965
https://pubmed.ncbi.nlm.nih.gov/18021319
https://pubmed.ncbi.nlm.nih.gov/18021319
Publikováno v:
The Journal of biological chemistry. 276(16)
Rim1 was identified in brain by its ability to bind Rab3a-GTP and has been postulated to be a Rab3a effector protein. Like Rabphilin3, it modulates secretion and contains a zinc finger and two C2 domains. We have investigated the structural basis for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f2b858a7d85c7158917e074268a4d70
https://pubmed.ncbi.nlm.nih.gov/11278839
https://pubmed.ncbi.nlm.nih.gov/11278839
Autor:
M A, Bittner, R W, Holz
Publikováno v:
The Journal of biological chemistry. 275(33)
alpha-Latrotoxin, a component of black widow spider venom, stimulates transmitter release from nerve terminals and intact chromaffin cells and enhances secretion from permeabilized chromaffin cells already maximally stimulated by Ca(2+). In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab25c5ed425a8efd089c49f5c399a5c8
https://pubmed.ncbi.nlm.nih.gov/10851245
https://pubmed.ncbi.nlm.nih.gov/10851245
Publikováno v:
The Journal of biological chemistry. 274(6)
Stimulation of neurotransmitter release by alpha-latrotoxin requires its binding to the calcium-independent receptor of alpha-latrotoxin (CIRL), an orphan neuronal G protein-coupled receptor. CIRL consists of two noncovalently bound subunits, p85, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee948bb15d926ea9ab9b28b830a4a742
https://pubmed.ncbi.nlm.nih.gov/9920906
https://pubmed.ncbi.nlm.nih.gov/9920906
Publikováno v:
The Journal of biological chemistry. 273(17)
In the present study we investigated the lipid binding characteristics of the C2 domains of Rabphilin3a. We found that the tandem C2 domain of Rabphilin3a specifically bound lipid vesicles containing phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49f4648562043d6f8e34d832a19d0457
https://pubmed.ncbi.nlm.nih.gov/9553075
https://pubmed.ncbi.nlm.nih.gov/9553075
Publikováno v:
Molecular pharmacology. 49(2)
Regulated exocytosis from bovine chromaffin cells is stimulated by the influx of Ca2+ through plasma membrane ion channels that are opened by nicotinic stimulation and/or depolarization. Recently, we developed a novel method that enabled us to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3e13d7b9035044ec274914616bcd06e
https://pubmed.ncbi.nlm.nih.gov/8632762
https://pubmed.ncbi.nlm.nih.gov/8632762
Publikováno v:
The Journal of biological chemistry. 270(28)
Rabphilin3a had been identified in brain as a Rab3a-binding protein and may serve as an effector for Rab3a function. We have cloned a splice variant of brain-Rabphilin3a from a bovine adrenal chromaffin cell cDNA library and investigated the function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::750ec83bbb5b34f2e9b4f98e1f47bf53
https://pubmed.ncbi.nlm.nih.gov/7622481
https://pubmed.ncbi.nlm.nih.gov/7622481
Publikováno v:
Methods in enzymology. 257
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f763d06c7da70ef00eba224ce45c61b8
https://pubmed.ncbi.nlm.nih.gov/8583925
https://pubmed.ncbi.nlm.nih.gov/8583925