Výsledky vyhledávání

16. The Use of Hydroxamic Acids to Block Electron Transport in Pathogenic African Trypanosomes

Autor: R. W. Grady, A. B. Clarkson

The aerobic and anaerobic pathways of glycolysis in Trypanosoma brucei brucei are blocked by a combination of salicylhydroxamic acid (SHAM) and glycerol, both in vitro and in vivo. To effect cures, however, SHAM must be administered in doses that cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e357fcedf3495f89adbe71583971243
https://doi.org/10.1159/000430639

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Epispadias Repair: Complete Penile Disassembly

Autor: R. W. Grady, P. C. Black, M. E. Mitchell

Publikováno v: Advanced Urology Surgery, Third Edition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c00a9ceead25f77525a7a27878ac4fa
https://doi.org/10.1002/9780470755914.ch34

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Primary Reconstruction of Cloacal Exstrophy

Autor: R. W. Grady, M. E. Mitchell, P. C. Black

Publikováno v: Advanced Urology Surgery, Third Edition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f8b74de5172e2212855d3d92c804c44
https://doi.org/10.1002/9780470755914.ch70

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Complete primary repair of exstrophy. Surgical technique

Autor: R W, Grady, M E, Mitchell

Publikováno v: The Urologic clinics of North America. 27(3)

The single-stage reconstructive approach to exstrophy evolved out of changes in the management of exstrophy. The success of Jeffs and others that functionally reconstructed the bladder of patients with exstrophy demonstrated that the approach was fea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4592391bb5453e9d6f6fa107c08d0400
https://pubmed.ncbi.nlm.nih.gov/10985156

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Long-term followup of the hematuria-dysuria syndrome

Autor: J, Chadwick Plaire, W T, Snodgrass, R W, Grady, M E, Mitchell

Publikováno v: The Journal of urology. 164(3 Pt 2)

The hematuria-dysuria syndrome is the most common reported complication of gastrocystoplasty. We reviewed our cases of gastrocystoplasty to determine the long-term incidence and significance of the syndrome.We performed a retrospective study of 78 pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b3d26a1509a20559da71bff8603d4da3
https://pubmed.ncbi.nlm.nih.gov/10958709

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Vaginal calculi secondary to partial vaginal outlet obstruction in pediatric patients

Autor: J C, Plaire, W T, Snodgrass, R W, Grady, M E, Mitchell

Publikováno v: The Journal of urology. 164(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::960be664324b09f56e54ceeebd9dac93
https://pubmed.ncbi.nlm.nih.gov/10840445

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Complete primary repair of exstrophy

Autor: R W, Grady, M E, Mitchell

Publikováno v: The Journal of urology. 162(4)

The surgical correction of bladder exstrophy to achieve continence with voiding remains a challenging problem for the urologist. Since 1989 we have performed complete primary repair for exstrophy based on the concept that the primary defect of bladde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e383bb27cd22d24333ff76c9b8fd5101
https://pubmed.ncbi.nlm.nih.gov/10492228

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Antiretroviral effects of deoxyhypusyl hydroxylase inhibitors: a hypusine-dependent host cell mechanism for replication of human immunodeficiency virus type 1 (HIV-1)

Autor: L, Andrus, P, Szabo, R W, Grady, A R, Hanauske, T, Huima-Byron, B, Slowinska, S, Zagulska, H M, Hanauske-Abel

Publikováno v: Biochemical pharmacology. 55(11)

The HIV-1 protein Rev, critical for translation of incompletely spliced retroviral mRNAs encoding capsid elements, requires a host cell protein termed "eukaryotic initiation factor 5A" (eIF-5A). This is the only protein containing hypusine, a lysine-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfcb76a9a32fd3c566ed49ed3b82417b
https://pubmed.ncbi.nlm.nih.gov/9714299

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Chelation therapy in beta-thalassemia: the benefits and limitations of desferrioxamine

Autor: P J, Giardina, R W, Grady

Publikováno v: Seminars in hematology. 32(4)

In summary, long-term studies of DFO therapy in multiply-transfused patients with beta-thalassemia major have clearly shown it to be generally safe and effective. Appropriate use of DFO can remove excess iron, prevent iron-induced organ damage, and i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88563521c2f235e0ec2fd823b1ec3218
https://pubmed.ncbi.nlm.nih.gov/8560288

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NF-kappa B transcription factor activation by hydrogen peroxide can be decreased by 2,3-dihydroxybenzoic acid and its ethyl ester derivative

Autor: Sylvie Legrand-Poels, R. W. Grady, Christine Sappey, Jacques Piette, Johan R. Boelaert

Publikováno v: Archives of biochemistry and biophysics. 321(1)

Reactive oxygen species like hydrogen peroxide (H2O2) have been shown to serve as messengers in the induction of NF-kappa B and, hence, in the activation and replication of human immunodeficiency virus type 1 (HIV-1) in human cells. Several antioxida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630c3688a090f3edd8dab15e71892717
https://pubmed.ncbi.nlm.nih.gov/7639530

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