Výsledky vyhledávání

Direct effect of the neurotoxicant acrylamide on kinesin-based microtubule motility

Autor: D W, Sickles, S T, Brady, A, Testino, M A, Friedman, R W, Wrenn

Publikováno v: Journal of neuroscience research. 46(1)

Acrylamide (ACR) is an environmental toxicant and prototypic tool for studying mechanisms of peripheral neuropathies. Reductions in fast anterograde axonal transport (faAXT) are thought to be a critical step leading to axonal degeneration. Kinesin an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11640f0689ccd3a9703d5d93001f621a
https://pubmed.ncbi.nlm.nih.gov/8892100

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Stimulation by phosphatidylserine and calmodulin of calcium-dependent phosphorylation of endogenous proteins from cerebral cortex

Autor: R W Wrenn, B C Wise, N Katoh, J.F. Kuo

Publikováno v: Journal of Biological Chemistry. 255:12042-12046

The Ca2+-dependent phosphorylation of a number of proteins in the cytosol of the rat or guinea pig cerebral cortex was profoundly stimulated by phosphatidylserine; calmodulin, on the other hand, had only a minimal effect. The Ca2+-dependent phosphory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82445546bf048a114332c6aefc517eac
https://doi.org/10.1016/s0021-9258(19)70241-5

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Stimulation by phosphatidylserine and calmodulin of calcium-dependent phosphorylation of endogenous proteins from cerebral cortex

Autor: R W, Wrenn, N, Katoh, B C, Wise, J F, Kuo

Publikováno v: The Journal of biological chemistry. 255(24)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8f20d82b57afde50c8e2558146fe825
https://pubmed.ncbi.nlm.nih.gov/7440585

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Inhibition by adriamycin of calmodulin-sensitive and phospholipid-sensitive calcium-dependent phosphorylation of endogenous proteins from heart

Autor: J.F. Kuo, R W Wrenn, N Katoh, B C Wise

Adriamycin, a lipid-interacting anti-cancer agent, was found to inhibit phospholipid-sensitive Ca2+-dependent phosphorylation of endogenous proteins from the cytosol of the guinea-pig heart. The drug, unexpectedly, also inhibited phosphorylation of s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46db21bd9f5f01538f7ca62501c93105
https://europepmc.org/articles/PMC1163227/

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Effects of parathyroid hormone on cyclic AMP, cyclic GMP, and efflux of calcium in isolated renal tubules

Autor: D M, Biddulph, R W, Wrenn

Publikováno v: Journal of cyclic nucleotide research. 3(2)

The effects of parathyroid hormone (PTH) on concentrations of cyclic AMP and cyclic GMP were investigated in isolated renal cortical tubules from hamsters. Efflux of 45Ca from tubules was compared to temporal changes in both cyclic nucleotide concent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::64ecc908bdc19305b58b636ce6a3bc0a
https://pubmed.ncbi.nlm.nih.gov/195984

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Pharmacology of the cardiac endocrine system

Autor: Howard Schomer, Walter H. Newman, Mark G. Currie, William F. Oehlenschlager, R. W. Wrenn, Catherine E. Lofton

Publikováno v: Functional Morphology of the Endocrine Heart ISBN: 9783642724343

Over the past six years, data and information have accumulated which indicate that the atrial endocrine system and its secreted bioactive peptide(s) are important participants in the regulation of blood pressure and fluid and electrolyte homeostasis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdf873afff86e1a5ed2ea0e8a4f7cd06
https://doi.org/10.1007/978-3-642-72432-9_13

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Redistribution of phospholipid/calcium-dependent protein kinase and altered phosphorylation of its soluble and particulate substrate proteins in phorbol ester-treated rat pancreatic acini

Autor: M W, Wooten, R W, Wrenn

Publikováno v: Cancer research. 45(8)

The biological activity of phorbol esters, such as 12-O-tetra-decanoylphorbol-13-acetate, have been associated with activation of phospholipid/Ca2+-dependent protein kinase. Treatment of rat pancreatic acini with 12-O-tetradecanoylphorbol-13-acetate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75df479b8c631303c798c67dc05312c8
https://pubmed.ncbi.nlm.nih.gov/2410105

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Dual calcium-dependent protein phosphorylation systems in pancreas and their differential regulation by polymyxin B1

Autor: R W, Wrenn, M W, Wooten

Publikováno v: Life sciences. 35(3)

Both phospholipid/calcium (PL/Ca2+) activated and calmodulin/Ca2+ (CaM/Ca2+)activated protein kinase systems were found in rat pancreatic extracts treated with Sephadex G-25. At least four substrate proteins for PL/Ca2+-activated kinase and one for a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::16e72379e3eeee72640000c48bab8fe0
https://pubmed.ncbi.nlm.nih.gov/6205237

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Correlation between cyclic AMP levels and calcium efflux in isolated renal cortical tubules

Autor: R W, Wrenn, D M, Biddulph

Publikováno v: Journal of cyclic nucleotide research. 5(3)

Isolated renal cortical tubules from male hamsters were utilized to examine the possible relationship between cyclic AMP (cAMP) and efflux of calcium. Both parathyroid hormone (PTH) and prostaglandin E1 (PGE1) produced dose-related increases in cAMP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::befb9b1968a3ffca0453d3de0924fe17
https://pubmed.ncbi.nlm.nih.gov/225358

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