Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R W, Nickells"'
Publikováno v:
Developmental Genetics. 14:51-57
Heat-shocked Xenopus embryos have an unusually complex heat shock response. The dominant heat shock protein (Hsp) has a relative molecular mass (Mr) of 62,000 D (Hsp62). Affinity-purified IgGs against the glycolytic enzyme pyruvate kinase (PK; EC 2.7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412c2cd7ff62ee01b04c5495c0fd5297
https://doi.org/10.1002/dvg.1020140107
https://doi.org/10.1002/dvg.1020140107
Publikováno v:
Molecular vision. 7
The temporal series of molecular events that occur in dying retinal ganglion cells is poorly understood. We have examined the change in expression of a normally-expressed ganglion cell marker gene, Thy1, relative to the kinetics of cell loss caused b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::545ff6f2dc2dcb1681c0cec3aec7e50f
https://pubmed.ncbi.nlm.nih.gov/11509915
https://pubmed.ncbi.nlm.nih.gov/11509915
Autor:
S, Sarkar, K P, Jülicher, M S, Burger, V, Della Valle, C J, Larsen, T R, Yeager, T B, Grossman, R W, Nickells, C, Protzel, D F, Jarrard, C A, Reznikoff
Publikováno v:
Cancer research. 60(14)
Inactivation of both the pRb (pRb-cyclin D1/cyclin-dependent kinase 4/6-p16) and p53 (p53-p21(WAF1)-p14(ARF)) pathways is thought to be essential for immortalization in vitro and malignant transformation in vivo. We identified different combinations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3b8112422a27880f2452955c18de14a
https://pubmed.ncbi.nlm.nih.gov/10919661
https://pubmed.ncbi.nlm.nih.gov/10919661
Autor:
R W, Nickells
Publikováno v:
Survey of ophthalmology. 43
Apoptosis is a genetically controlled form of cell death that ganglion cells undergo during normal development of the retina and in diseases affecting the optic nerve, such as glaucoma. This mechanism of cell death is controlled by specific genes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdeabae4fb624635ad5b6c3bd59e9e53
https://pubmed.ncbi.nlm.nih.gov/10416758
https://pubmed.ncbi.nlm.nih.gov/10416758
Publikováno v:
Investigative ophthalmologyvisual science. 40(5)
Retinal ganglion cells die by apoptosis during development and after trauma such as axonal damage and exposure to excitotoxins. Apoptosis is associated with changes in the expression of genes that regulate this process. The genes that regulate apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba5d409b31b71873347b1675590cd6e8
https://pubmed.ncbi.nlm.nih.gov/10102300
https://pubmed.ncbi.nlm.nih.gov/10102300
Publikováno v:
Investigative ophthalmologyvisual science. 38(12)
Retinal ganglion cells die by apoptosis after axotomy, and this process may reflect altered expression of cell-death genes. Several of these genes, including bcl-2, bcl-x, and bax, share homology at the amino acid level in the BH1 and BH2 domains, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a96fa53edcbf098b79bdd17f7e509b7
https://pubmed.ncbi.nlm.nih.gov/9375574
https://pubmed.ncbi.nlm.nih.gov/9375574
Autor:
R W, Nickells
Publikováno v:
Journal of glaucoma. 5(5)
Research on the mechanism of cell death in experimental glaucoma indicates that ganglion cells die by apoptosis. Several stimuli may account for the activation of apoptosis in glaucoma, including neurotrophin deprivation caused by blockage of retrogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17675dd78a399ff46a4db9f78c817284
https://pubmed.ncbi.nlm.nih.gov/8897235
https://pubmed.ncbi.nlm.nih.gov/8897235
Publikováno v:
Investigative ophthalmologyvisual science. 36(5)
To investigate whether retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.Chronic elevated eye pressure was produced in 20 monkey eyes, and the optic nerve was transected unilaterally in the orbit of 10 monkeys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4893b417a163a57a2c8c1e583b585e07
https://pubmed.ncbi.nlm.nih.gov/7706025
https://pubmed.ncbi.nlm.nih.gov/7706025
Publikováno v:
Developmental biology (New York, N.Y. : 1985). 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::904d5e8b664bad005c761a63a8e78294
https://pubmed.ncbi.nlm.nih.gov/2696497
https://pubmed.ncbi.nlm.nih.gov/2696497