Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R W, Lappe"'
Publikováno v:
Circulation Research. 72:1091-1102
Recombinant desulfatohirudin (HI), a potent and specific thrombin inhibitor, was compared with heparin (HE) as an adjunct to streptokinase thrombolysis. In pentobarbital-anesthetized dogs, an occlusive thrombus (whole blood+thrombin) was introduced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46211e5fb75ec9a0e00076104a875f52
https://doi.org/10.1161/01.res.72.5.1091
https://doi.org/10.1161/01.res.72.5.1091
Publikováno v:
Journal of Cardiovascular Pharmacology. 22:S149-S153
Endothelin (ET) induces depolarization and contraction of glomerular mesangial cells (MCs), thereby influencing intraglomerular hemodynamics and filtration rate. In an attempt to clarify the ionic mechanism by which ET regulates MC function, we exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6c303a2837fe6e8cf3ef39ae1caf77
https://doi.org/10.1097/00005344-199322008-00040
https://doi.org/10.1097/00005344-199322008-00040
Autor:
R E, Chatelain, R D, Ghai, A J, Trapani, L M, Odorico, B N, Dardik, S, De Lombaert, R W, Lappe, C A, Fink
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(3)
Dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitors, by decreasing angiotensin-II production and by preventing the degradation of atrial natriuretic peptide (ANP), may be useful for the treatment of hypertension and conges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d9ea082891221a423242bc16a42d171
https://pubmed.ncbi.nlm.nih.gov/9495857
https://pubmed.ncbi.nlm.nih.gov/9495857
Autor:
A J, Trapani, J L, Balwierczak, R W, Lappe, J L, Stanton, S C, Graybill, M F, Hopkins, P, Savage, D M, Sperbeck, A Y, Jeng
Publikováno v:
Biochemistry and molecular biology international. 31(5)
The IC50 values of phosphoramidon, CGS 25015, CGS 26129, thiorphan and benazeprilat for inhibition of endothelin converting enzyme partially purified from porcine aortic endothelial cells were 3.5, 18, 58,100 and100 microM, respectively. A similar ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6de7a89d81673f13f68730671c7f9c52
https://pubmed.ncbi.nlm.nih.gov/8136704
https://pubmed.ncbi.nlm.nih.gov/8136704
Publikováno v:
Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 11(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e3f76efb9d63da4979a113b8815b4de
https://pubmed.ncbi.nlm.nih.gov/8158354
https://pubmed.ncbi.nlm.nih.gov/8158354
Autor:
L. Li, T. A. Leedom, V. R. Doppalapudi, J. D. Rizzo, N. J. Levin, K. Johnson, C. W. Bradshaw, J. Lai, R. W. Lappe, G. Woodnutt
Publikováno v:
Journal of Clinical Oncology. 25:14011-14011
14011 Background: TSP-1 reduces angiogenesis and tumor growth in vivo, and induces endothelial cell apoptosis in vitro. CVX-045 was produced by fusing a peptide derived from TSP-1, known to have anti-vascular activity, to a proprietary monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82127ac0bb3485f6c38748c07299d15d
https://doi.org/10.1200/jco.2007.25.18_suppl.14011
https://doi.org/10.1200/jco.2007.25.18_suppl.14011
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 14:137-140
SUMMARY 1. The hemodynamic responses to i.v. infusion of 0.3 and 0.6 μg/kg per min of human atrial natriuretic factor (hANF [102–126]) in intact, conscious, one-kidney, perinephritic, hypertensive beagles were examined and compared with the respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a60aa9debb0d950f95a6cc0eec5805
https://doi.org/10.1111/j.1440-1681.1987.tb00968.x
https://doi.org/10.1111/j.1440-1681.1987.tb00968.x
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 249:R781-R786
Previous studies have demonstrated that infusion of synthetic atriopeptin II (AP II) lowered arterial pressure, reduced regional blood flow, and increased total peripheral and regional vascular resistances in conscious spontaneously hypertensive rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7203f3022a8d58c8669a2de79f9e10
https://doi.org/10.1152/ajpregu.1985.249.6.r781
https://doi.org/10.1152/ajpregu.1985.249.6.r781
Publikováno v:
The American journal of physiology. 249(4 Pt 2)
Surgical denervation of kidneys results in interruption of both afferent and efferent renal nerves. We attempted selective efferent renal denervation in rats by slow infusions of 6-hydroxydopamine (6-OHDA) into the right renal artery. Integrity of ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af1721ec635fcb20f44e24b64b4f3bd
https://pubmed.ncbi.nlm.nih.gov/3931485
https://pubmed.ncbi.nlm.nih.gov/3931485
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 235(3)
The present study was designed to examine the effects of two different converting enzyme inhibitors on regional hemodynamics in conscious spontaneously hypertensive rats. Rats were chronically instrumented with miniaturized pulsed Doppler flow probes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68d9e1649cecb0a6e365ed33ad916226
https://pubmed.ncbi.nlm.nih.gov/3001271
https://pubmed.ncbi.nlm.nih.gov/3001271