Zobrazeno 1 - 10
of 31
pro vyhledávání: '"R W, Kierstead"'
Publikováno v:
Journal of Medicinal Chemistry. 17:337-342
Autor:
R W, Guthrie, G L, Kaplan, F A, Mennona, J W, Tilley, R W, Kierstead, J G, Mullin, R A, LeMahieu, S, Zawoiski, M, O'Donnell, H, Crowley
Publikováno v:
Journal of Medicinal Chemistry. 32:1820-1835
A series of N-[4-(3-pyridinyl)butyl]-5,5-disubstituted-pentadienamides was prepared and evaluated for PAF-antagonist activity. Compounds were assayed in vitro in a PAF-binding assay employing washed, whole dog platelets as the receptor source and in
Autor:
Mullin John Guilfoyle, Herman J. Crowley, Robert William Guthrie, L. C. Blaber, A. Faraone, B. Simko, Francis A. Mennona, R. W. Kierstead
Publikováno v:
Journal of Medicinal Chemistry. 26:1561-1569
A series of binary (aryloxy)propanolamines has been prepared and examined in vitro and in vivo for beta-adrenoreceptor blocking activity. These symmetrical compounds consist of two (S)-(phenyloxy)propanolamine pharmacophores coupled through alkylened
Publikováno v:
Journal of Medicinal Chemistry. 15:1056-1060
Autor:
R. W. Kierstead, Donald J. Cram
Publikováno v:
Journal of the American Chemical Society. 77:1186-1190
Publikováno v:
Journal of the American Chemical Society. 80:3126-3132
Publikováno v:
Tetrahedron. 2:1-57
Publikováno v:
Canadian Journal of Chemistry. 37:679-699
The stable alkylation products of alkyl and aryl nitrosohydroxylamines seem to exist in a hitherto unknown structure, the diimide dioxide linkage. The alternative possibility is the alkyl diazotate monoxide structure, but the latter cannot account fo
Publikováno v:
Chemischer Informationsdienst. 12
Autor:
R A, LeMahieu, H A, Ax, J F, Blount, M, Carson, C W, Despreaux, D L, Pruess, J P, Scannell, F, Weiss, R W, Kierstead
Publikováno v:
The Journal of antibiotics. 29(7)
A new antibiotic, 3-O-oleandrosyl-5-O-desosaminylerythronolide A oxime (3) was produced from erythronolide A oxime (1) by the oleandomycin-producing culture, Streptomyces antibioticus ATCC 11891. The structure of 3 was determined by degradative studi