Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R W, Curley"'
Autor:
H, Abou-Issa, R W, Curley, G A, Alshafie, K L, Weiss, M, Clagett-Dame, J S, Chapman, S M, Mershon
Publikováno v:
Anticancer research. 21(6A)
The antitumor effects of N-(4-hydroxyphenyl)retinamide (4-HPR), and its stable C-linked analog, 4-hydroxybenzylretinone (4-HBR) on the regression of established 7,12-dimethylbenz(a)anthracene(DMBA)-induced rat mammary tumors were compared. 4-HBR is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d56c831ed817081bf42398590353e160
https://pubmed.ncbi.nlm.nih.gov/11911255
https://pubmed.ncbi.nlm.nih.gov/11911255
Autor:
K L, Weiss, G, Alshafie, J S, Chapman, S M, Mershon, H, Abou-Issa, M, Clagett-Dame, R W, Curley
Publikováno v:
Bioorganicmedicinal chemistry letters. 11(12)
The synthesis of a nonhydrolyzable, carbon-linked analogue (4-HBR) of the retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) using Umpolung methods is described. Preliminary studies of biological activity show 4-HBR is similar to 4-HPR in its actions alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc7333b3a1126bcc2ac03d2e33d96f66
https://pubmed.ncbi.nlm.nih.gov/11412986
https://pubmed.ncbi.nlm.nih.gov/11412986
Publikováno v:
Anticancer research. 19(2A)
The long term chemopreventive effects of the N-(4-hydroxyphenyl) retinamide-O-glucuronide (4-HPROG), and its stable C-linked benzyl glucuronide analog, retinamidobenzyl glucuronide (4-HPRCG) on the growth and development of 7,12-dimethylbenz[a]anthra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cea502223149c6a75e15dba16deef2ce
https://pubmed.ncbi.nlm.nih.gov/10368645
https://pubmed.ncbi.nlm.nih.gov/10368645
Publikováno v:
Pharmaceutical research. 16(5)
Vitamin A (retinol) and its metabolites comprise the natural retinoids. While the biological action of these molecules are thought to be primarily mediated by ca. 55 kDa nuclear retinoic acid receptors, a number of structurally similar 15-20 kDa prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::577f26c387e91254e28d755d6f79eed7
https://pubmed.ncbi.nlm.nih.gov/10350006
https://pubmed.ncbi.nlm.nih.gov/10350006
Publikováno v:
Anticancer research. 17(5A)
The growth inhibitory effects of N-(4- Hydroxyphenyl) retinamide (4-HPR) and its glucuronide derivative, N-(4-Hydroxyphenyl) retinamide-O-glucuronide (4-HPROG) on established DMBA induced rat mammary tumors were compared. The results indicate that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6edf50152287146a04f21834bbcf1c9
https://pubmed.ncbi.nlm.nih.gov/9413168
https://pubmed.ncbi.nlm.nih.gov/9413168
Publikováno v:
Anticancer research. 16(2)
The O-glucuronide analog of N-(4-hydroxyphenyl)retinamide (4-HPROG) has shown a greater chemopreventive activity than the parent N-(4-hydroxyphenyl)retinamide (4-HPR). However, this compound is relatively unstable. In order to improve stability and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06d5b7d74c0b7b8dfb1c862dace6f437
https://pubmed.ncbi.nlm.nih.gov/8687125
https://pubmed.ncbi.nlm.nih.gov/8687125
Publikováno v:
Anticancer research. 15(3)
The independent effects of the potential cancer chemopreventive agent calcium glucarate (CGT) when fed (128 mmol/kg diet) during the initiation (I), promotion (P) or (I+P) phases of 7,12-dimethylbenzanthracene-induced rat mammary carcinogenesis, was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d96f1c5185c08786ec9cb2748568421
https://pubmed.ncbi.nlm.nih.gov/7645962
https://pubmed.ncbi.nlm.nih.gov/7645962
Publikováno v:
ACS Symposium Series ISBN: 9780841227682
Food Phytochemicals for Cancer Prevention I: Fruits and Vegetables
Food Phytochemicals for Cancer Prevention I: Fruits and Vegetables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2bfdd744f6134f0d4bed8ad0e54bc28
https://doi.org/10.1021/bk-1994-0546.ch030
https://doi.org/10.1021/bk-1994-0546.ch030
In vivo use of N-(4-hydroxyphenyl retinamide)-0-glucuronide as a breast cancer chemopreventive agent
Publikováno v:
Anticancer research. 13(5A)
The inhibitory effects of N-(4-hydroxyphenyl) retinamide and its glucuronide derivative on the development and growth of 7,12-dimethylbenz (a) anthracene - induced rat mammary tumors in vivo were compared. The results indicate that the glucuronide ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29c5cb9f15aef9399e178a02a1a4ec82
https://pubmed.ncbi.nlm.nih.gov/8239515
https://pubmed.ncbi.nlm.nih.gov/8239515
Autor:
H, Abou-Issa, C, Dwivedi, R W, Curley, R, Kirkpatrick, A, Koolemans-Beynen, F N, Engineer, K A, Humphries, W, el-Masry, T E, Webb
Publikováno v:
Anticancer research. 13(2)
The biochemical basis for the cancer chemopreventive and anti-cancer activities of glucarate, retinoids (13-cis-retinoic acid, hydroxyphenyl retinamide) and their synergistic combination, has been evaluated. Neither alone nor in combination did these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c15bcceaae0a617da489e949372c8411
https://pubmed.ncbi.nlm.nih.gov/8517653
https://pubmed.ncbi.nlm.nih.gov/8517653