Zobrazeno 1 - 10 of 86 pro vyhledávání: '"R Voges"'
1
Akademický článek
Irreversible inhibition of hepatic fatty acid salt uptake by photoaffinity labeling with 11, 11-azistearate
Autor: W Schmider, A Fahr, R Voges, W Gerok, G Kurz
Publikováno v: Journal of Lipid Research, Vol 37, Iss 4, Pp 739-753 (1996)
In order to have a model compound for detection of proteins involved in transport and metabolism of long-chain fatty acid salts by photoaffinity labeling 11,11-azistearate and 11,11-azi[G-3H]stearate (specific radioactivity 2.78 TBq/mmol) were synthe
Externí odkaz: https://doaj.org/article/87bddda8e19449beb25e4820c127a847
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2
Akademický článek
Synthesis of a metabolically stable modified long-chain fatty acid salt and its photolabile derivative
Autor: GH Stoll, R Voges, W Gerok, G Kurz
Publikováno v: Journal of Lipid Research, Vol 32, Iss 5, Pp 843-857 (1991)
An analogue of the long-chain fatty acid salt, sodium stearate, was synthesized in which the hydrogen atoms at carbons 2, 3, and 18 were replaced by fluorine. The key step in the synthesis was the addition of 3-iodo-2,2,3,3-tetrafluoropropanoic acid
Externí odkaz: https://doaj.org/article/f5643b1bde0e4035bdf93a59b0dc8e93
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3
Akademický článek
Bi-level VNS therapy with different therapy modes at night and daytime improves seizures and quality of life in a patient with drug-resistant epilepsy
Autor: Berthold R. Voges
Publikováno v: Epilepsy & Behavior Reports, Vol 24, Iss , Pp 100633- (2023)
Induction or aggravation of sleep apnea is a known side effect of vagus nerve stimulation (VNS). We report the case of a 44 year old male with drug-resistant epilepsy and depression who did not experience any seizure reduction after 1 year of VNS but
Externí odkaz: https://doaj.org/article/a45c38bb11544be3878c158b1ba75d03
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4
Akademický článek
TIMESTAMP OFFSET DETERMINATION BETWEEN AN ACTUATED LASER SCANNER AND ITS CORRESPONDING MOTOR
Autor: R. Voges, C. S. Wieghardt, B. Wagner
Publikováno v: ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol IV-1-W1, Pp 99-106 (2017)
Motor actuated 2D laser scanners are key sensors for many robotics applications that need wide ranging but low cost 3D data. There exist many approaches on how to build a 3D laser scanner using this technique, but they often lack proper synchronizat
Externí odkaz: https://doaj.org/article/c179cd1a9f6048ec98ef6de2ede56640
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5
Akademický článek
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7
The outstanding metabolic stability of a14C-labeled?-nonapeptide in rats -in vitro andin vivo pharmacokinetic studies
Autor: Bernard Wirz, Maria Ines Rodriguez Perez, Jens Frackenpohl, Ralph Woessner, Dieter Seebach, Hansjörg Wiegand, Alain Schweitzer, Gian Camenisch, R. Voges, Gerhard Gross, Per I. Arvidsson
Publikováno v: Biopharmaceutics & Drug Disposition. 23:251-262
In vitro studies: In CaCo-2 cell monolayers the β-nonapeptide H(β-HAla-β-HLys-β-HPhe)3-OH·4HCl (1), 14C-labeled on both C atoms of the CH2–CO moiety of the central β-HPhe residue, showed a low intrinsic permeability (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf47328a724f450a43a73e848c003d4f
https://doi.org/10.1002/bdd.334
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9
Synthesis of [S-[1-14C]Val7]VALSPODAR application of (+)/(?)-[13,14Cn]BABS and (+)/(?)-[13,14Cn]DPMGBS, part 4
Autor: Y. Metz, B. Kohler, R. Voges, P. Burtscher, R. Wenger
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 43:205-216
VALSPODAR 2, a cyclic undecapeptide anticancer drug derived from natural Cyclosporin D10, was labelled with Carbon-14 in a nine step synthesis. The sequence started from (−)-[1-14C]BABS 1a, a highly versatile two-carbon synthon for a broad spectrum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d459f08b478032531396e0f61f70f43
https://doi.org/10.1002/(sici)1099-1344(20000315)43:3<205::aid-jlcr303>3.0.co
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10
Synthesis of [14C2]taxol: application of (+)/(?)-[13,14Cn]BABS,part 3
Autor: I. Rodriguez, R. Voges
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 43:169-176
A multiple step stereoselective procedure was successfully applied to doubly C-14 labelled Taxol 1 in its pharmacologically essential (2R,3S)-N-benzoyl-3-phenylisoserine side chain. A highly stereocontrolled aldol reaction of internally developed (+)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69c8005938f0eefea46adb4c5d4192c1
https://doi.org/10.1002/(sici)1099-1344(200002)43:2<169::aid-jlcr302>3.0.co
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