Zobrazeno 1 - 3
of 3
pro vyhledávání: '"R V Merrihew"'
Publikováno v:
Nucleic Acids Research. 24:746-753
Several DNA sequence elements are thought to stimulate homologous recombination, illegitimate recombination, or both in mammalian cells. Some are implicated by their recurrence around rearrangement breakpoints, others by their effects on recombinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db052babafebb5c00865722ec43c5ba
https://doi.org/10.1093/nar/24.4.746
https://doi.org/10.1093/nar/24.4.746
To examine the mechanisms of recombination governing the illegitimate integration of transfected DNA into a mammalian genome, we developed a cell system that selects for integration events in defined genomic regions. Cell lines with chromosomal copie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5190cde5aefe040cfde190d13bddbbf4
https://europepmc.org/articles/PMC230973/
https://europepmc.org/articles/PMC230973/
Publikováno v:
Somatic cell and molecular genetics. 21(5)
The FLP/FRT site-specific recombination system was established and characterized at the APRT gene in CHO cells. Targeting frequencies with FLP-stimulation were about 1 to 5 X 10(-5), which were 6-22-fold above gene targeting frequencies in the absenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fe4c12e9f21eb8e166b069c1c94ca3
https://pubmed.ncbi.nlm.nih.gov/8619127
https://pubmed.ncbi.nlm.nih.gov/8619127