Zobrazeno 1 - 4
of 4
pro vyhledávání: '"R V, D'Elia"'
Autor:
Ruth E. Thom, R V. D’Elia
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
New and emerging pathogens, such as SARS-CoV2 have highlighted the requirement for threat agnostic therapies. Some antibiotics or antivirals can demonstrate broad-spectrum activity against pathogens in the same family or genus but efficacy can quickl
Externí odkaz:
https://doaj.org/article/7a9b5707e5a9465096e217273763504b
Autor:
R. E. Thom, E. D. Williamson, J. Casulli, W. A. Butcher, G. Burgess, T. R. Laws, P. Huxley, R. Ashfield, M. A. Travis, R. V. D’Elia
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Antimicrobial resistance continues to be a global issue. Pathogens, such as Burkholderia pseudomallei, have evolved mechanisms to efflux certain antibiotics and manipulate the host response. New treatment strategies are therefore required, s
Externí odkaz:
https://doaj.org/article/b667d7a76d8f4c54b41683b6698cc808
Autor:
J. Casulli, M. E. Fife, S. A. Houston, S. Rossi, J. Dow, E. D. Williamson, G. C Clark, T. Hussell, R. V. D’Elia, M. A Travis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The authors show that the CD200 receptor (CD200R) promotes effective clearance of pulmonary Francisella tularensis infection in knock out mice. This result is unexpected as CD200R is known to dampen pulmonary immune responses, and these data suggest
Externí odkaz:
https://doaj.org/article/863531790019429fb219fb31b164b0b1
Autor:
J, Casulli, M E, Fife, S A, Houston, S, Rossi, J, Dow, E D, Williamson, G C, Clark, T, Hussell, R V, D'Elia, M A, Travis
Publikováno v:
Nature Communications
Pulmonary immune control is crucial for protection against pathogens. Here we identify a pathway that promotes host responses during pulmonary bacterial infection; the expression of CD200 receptor (CD200R), which is known to dampen pulmonary immune r