Zobrazeno 1 - 8
of 8
pro vyhledávání: '"R V, Chari"'
Publikováno v:
International journal of cancer. 73(6)
Folate receptor is over-expressed in a variety of carcinomas. To design a cytotoxic drug that would selectively target these carcinomas, we synthesized folate-maytansinoids. These drugs showed high affinity toward folate receptor, appeared to enter c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68c0382c1a9f24b13843b95ea1cbe188
https://pubmed.ncbi.nlm.nih.gov/9399666
https://pubmed.ncbi.nlm.nih.gov/9399666
Autor:
R V, Chari, K A, Jackel, L A, Bourret, S M, Derr, B M, Tadayoni, K M, Mattocks, S A, Shah, C, Liu, W A, Blättler, V S, Goldmacher
Publikováno v:
Cancer research. 55(18)
Bis-indolyl-(seco)-1,2,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on e compounds are synthetic analogues of CC-1065 that are highly cytotoxic toward a broad spectrum of tumor cell lines. One of these compounds, called DC1, was conjugated to antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49e7c87eb0ca3c6501d90e3e1d783b97
https://pubmed.ncbi.nlm.nih.gov/7545085
https://pubmed.ncbi.nlm.nih.gov/7545085
Autor:
R V, Chari, B A, Martell, J L, Gross, S B, Cook, S A, Shah, W A, Blättler, S J, McKenzie, V S, Goldmacher
Publikováno v:
Cancer research. 52(1)
The potential of immunoconjugates of cytotoxic drugs for the treatment of cancer has not yet been realized owing to the difficulty of delivering therapeutic concentrations of these drugs to the target cells. In an effort to overcome this problem we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::415c39ce9f076a4642c326480e3244ba
https://pubmed.ncbi.nlm.nih.gov/1727373
https://pubmed.ncbi.nlm.nih.gov/1727373
Publikováno v:
Journal of Biological Chemistry. 258:6823-6826
The paramagnetic effects of Mn2+ . glyoxalase I on the 13C relaxation rates of the reaction product, S-(D-lactoyl)glutathione, separately enriched in the lactoyl carbonyl (C-1) and hydroxymethylene (C-2) carbons, have been measured at 62.8 MHz. The 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::783243c865dcb3e07fe616f821beb185
https://doi.org/10.1016/s0021-9258(18)32296-8
https://doi.org/10.1016/s0021-9258(18)32296-8
Publikováno v:
The Journal of biological chemistry. 258(11)
The paramagnetic effects of Mn2+ . glyoxalase I on the 13C relaxation rates of the reaction product, S-(D-lactoyl)glutathione, separately enriched in the lactoyl carbonyl (C-1) and hydroxymethylene (C-2) carbons, have been measured at 62.8 MHz. The 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1821a27672f441c1b66853414067f036
https://pubmed.ncbi.nlm.nih.gov/6853506
https://pubmed.ncbi.nlm.nih.gov/6853506
Autor:
R V, Chari, J W, Kozarich
Publikováno v:
The Journal of biological chemistry. 256(19)
Fluoromethylglyoxal in the presence of glutathione has been shown to undergo a novel glyoxalase I-catalyzed product partitioning to S-fluorolactoylglutathione and S-pyruvylglutathione with fluoride elimination. While the partition ratio (fluoride eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c11f351b365fa7459322ffe3e57b4b83
https://pubmed.ncbi.nlm.nih.gov/7024272
https://pubmed.ncbi.nlm.nih.gov/7024272
Autor:
R V, Chari, A, Mookerjee
Publikováno v:
Indian journal of biochemistrybiophysics. 12(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::720bc1b9fdb11fedb62a882d4993c85c
https://pubmed.ncbi.nlm.nih.gov/1240866
https://pubmed.ncbi.nlm.nih.gov/1240866
Autor:
J W Kozarich, R V Chari
Publikováno v:
Journal of Biological Chemistry. 256:9785
Fluoromethylglyoxal in the presence of glutathione has been shown to undergo a novel glyoxalase I-catalyzed product partitioning to S-fluorolactoylglutathione and S-pyruvylglutathione with fluoride elimination. While the partition ratio (fluoride eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8982d3e5eab65f7f8a0283c68bbaf18c
https://doi.org/10.1016/s0021-9258(19)68690-4
https://doi.org/10.1016/s0021-9258(19)68690-4