Zobrazeno 1 - 10
of 95
pro vyhledávání: '"R Untch"'
Autor:
Benjamin A. Nacev, Francisco Sanchez-Vega, Shaleigh A. Smith, Cristina R. Antonescu, Evan Rosenbaum, Hongyu Shi, Cerise Tang, Nicholas D. Socci, Satshil Rana, Rodrigo Gularte-Mérida, Ahmet Zehir, Mrinal M. Gounder, Timothy G. Bowler, Anisha Luthra, Bhumika Jadeja, Azusa Okada, Jonathan A. Strong, Jake Stoller, Jason E. Chan, Ping Chi, Sandra P. D’Angelo, Mark A. Dickson, Ciara M. Kelly, Mary Louise Keohan, Sujana Movva, Katherine Thornton, Paul A. Meyers, Leonard H. Wexler, Emily K. Slotkin, Julia L. Glade Bender, Neerav N. Shukla, Martee L. Hensley, John H. Healey, Michael P. La Quaglia, Kaled M. Alektiar, Aimee M. Crago, Sam S. Yoon, Brian R. Untch, Sarah Chiang, Narasimhan P. Agaram, Meera R. Hameed, Michael F. Berger, David B. Solit, Nikolaus Schultz, Marc Ladanyi, Samuel Singer, William D. Tap
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Sarcomas are rare tumours with many different subtypes and clinical outcomes; a broader knowledge of their genetic features is required. Here, the authors analyse 2138 soft tissue and bone sarcomas across 45 subtypes using MSK-IMPACT targeted sequenc
Externí odkaz:
https://doaj.org/article/89c42dddd0f647ee90d7805699d564f6
Publikováno v:
Journal of Breast Cancer Research. 3:4-7
The recent development of the International Medullary Thyroid Cancer Grading System (IMTCGS) provided clinicians with a tool to predict for disease outcomes after undergoing resection based on histologic features. However, its impact on the clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::900ce2c1e8ec91330b4a357d96935e3c
https://doi.org/10.46439/breastcancer.3.017
https://doi.org/10.46439/breastcancer.3.017
Autor:
Chang S. Chan, Saurabh V. Laddha, Peter W. Lewis, Matthew S. Koletsky, Kenneth Robzyk, Edaise Da Silva, Paula J. Torres, Brian R. Untch, Janet Li, Promita Bose, Timothy A. Chan, David S. Klimstra, C. David Allis, Laura H. Tang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
In pancreatic neuroendocrine tumors (PanNETs) ATRX, DAXX, and MEN1 are commonly mutated (A-D-M mutant PanNETs). Here, the authors find in a cohort of PanNETS 58% are A-D-M mutant PanNETs, with a worse clinical outcome and differences in gene expressi
Externí odkaz:
https://doaj.org/article/91a16d51722c4f0dab5944814d57ad6b
Autor:
Luc G.T. Morris, James A. Fagin, Timothy A. Chan, Alan L. Ho, Eric J. Sherman, Richard J. Wong, Snjezana Dogan, Vladimir Makarov, Neal Patel, Zaineb Nadeem, Cristina Valero, Fengshen Kuo, Catherine Han, Ronald Ghossein, Bin Xu, Brian R. Untch, Mark Lee
Targeted inhibition of BRAF V600E achieves tumor control in a subset of advanced thyroid tumors. Nearly all tumors develop resistance, and some have been observed to subsequently undergo dedifferentiation. The molecular alterations associated with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dff8eee2d1cfea9be68c75d008bf1a6
https://doi.org/10.1158/1541-7786.c.6545222
https://doi.org/10.1158/1541-7786.c.6545222
Autor:
Luc G.T. Morris, James A. Fagin, Timothy A. Chan, Alan L. Ho, Eric J. Sherman, Richard J. Wong, Snjezana Dogan, Vladimir Makarov, Neal Patel, Zaineb Nadeem, Cristina Valero, Fengshen Kuo, Catherine Han, Ronald Ghossein, Bin Xu, Brian R. Untch, Mark Lee
Supplemental Figure 1. Increased clonal heterogeneity in anaplastic metastases (ATC Met 1, 5 clones Supplemental Figure 2. Copy-number alterations for the pre-vemurafenib papillary thyroid carcinoma sample Supplemental Figure 3. Differentially expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c5d6c6e4e91b5d60746945a91c50f3
https://doi.org/10.1158/1541-7786.22526813.v1
https://doi.org/10.1158/1541-7786.22526813.v1
Autor:
Luc G.T. Morris, James A. Fagin, Timothy A. Chan, Alan L. Ho, Eric J. Sherman, Richard J. Wong, Snjezana Dogan, Vladimir Makarov, Neal Patel, Zaineb Nadeem, Cristina Valero, Fengshen Kuo, Catherine Han, Ronald Ghossein, Bin Xu, Brian R. Untch, Mark Lee
Supplemental Table 1. Genomic alterations observed in MSK-THY1 Supplemental Table 2. Cellular prevalence of single nucleotide variants in MSK-THY Supplemental Table 3. Normalized gene expression data from patient MSK-THY1 Supplemental Table 4. Mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5415df00bf8f29141ac82fbaf104399b
https://doi.org/10.1158/1541-7786.22526810.v1
https://doi.org/10.1158/1541-7786.22526810.v1
Autor:
James A. Fagin, Ronald Ghossein, Filippo Giancotti, Kety H. Huberman, Adriana Heguy, Agnes Viale, Suresh C. Jhanwar, Yuqiang Fang, Gisele Oler, Yogindra Persaud, Barry S. Taylor, Ian Ganly, Vicki E. Smith, Francesca Voza, Jeffrey A. Knauf, Iňigo Landa, Brian R. Untch, Julio C. Ricarte-Filho, Maria E.R. Garcia-Rendueles
Supplementary Figure S1. Loss of heterozygosity of Ch22q genes in poorly differentiated (PDTC) and anaplastic thyroid cancers (ATC). Supplementary Figure S2. Focal NF2-exon 4 homozygous deletion in KHM-5M anaplastic thyroid cancer cells. Supplementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00432f909159d62c37d773b52e5a894b
https://doi.org/10.1158/2159-8290.22530699
https://doi.org/10.1158/2159-8290.22530699
Autor:
Chang S. Chan, Laura H. Tang, William D. Travis, John T. Poirier, Natasha Rekhtman, Hua Ke, Brian R. Untch, Kenneth Robzyk, Edaise M. da Silva, Saurabh V. Laddha
LC gene signature classifier and gene list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2545a55739adf2c049b3f90a4e0110c7
https://doi.org/10.1158/0008-5472.22422612.v1
https://doi.org/10.1158/0008-5472.22422612.v1
Autor:
Chang S. Chan, Laura H. Tang, William D. Travis, John T. Poirier, Natasha Rekhtman, Hua Ke, Brian R. Untch, Kenneth Robzyk, Edaise M. da Silva, Saurabh V. Laddha
TMA data for ASCL1 and S100 of 173 LCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5b9c78c313bf8c55f8c99db0e4a200
https://doi.org/10.1158/0008-5472.22422609
https://doi.org/10.1158/0008-5472.22422609
Autor:
Chang S. Chan, Laura H. Tang, William D. Travis, John T. Poirier, Natasha Rekhtman, Hua Ke, Brian R. Untch, Kenneth Robzyk, Edaise M. da Silva, Saurabh V. Laddha
Differentially expressed genes between AC and TC of LC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4db330943358cf38ebbc7cb6b8b469
https://doi.org/10.1158/0008-5472.22422606
https://doi.org/10.1158/0008-5472.22422606