Zobrazeno 1 - 10
of 88
pro vyhledávání: '"R U, Ostrovskaia"'
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 76(7)
The effect of dipeptidal neurotensine mimetic, N-caproyl-L-prolyl-L-tyrosine methyl ester (GZR-123, Dilept) and its main metabolite N-caproyl-L-prolyl-L-tyrosine (GZR-125) was evaluated at novel objects recognition test (NOR) in the male outbred rats
Autor:
R U, Ostrovskaia, Iu V, Vakhitova, M Kh, Salimgareeva, R S, Iamidanov, S V, Sadovnikov, I G, Kapitsa, S B, Seredenin
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(12)
The influence of noopept (N-phenylacetyl-L-prolylglycine ethyl ester, GVS-111)--a drug combining the nootrope and neuroprotector properties--on the activity of mitogen-activated protein kinases (MAPKs) and the level of NGF and BDNF gene and protein e
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(1)
Streptozotocin-intracerebroventricularly treated rats are proposed as an experimental model of sporadic Alzheimer disease (AD). Diabetogenic toxin streptozotocin (STZ) administered in both cerebral ventricles in a dose of 3 mg/kg decreases the expres
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 72(6)
The influence of the original dipeptide drug noopept, known to possess nootrope, neuroprotector, and anxiolytic properties, on the anticonvulsant activity of the antiepileptic drug valproate has been studied on the model of corazole-induced convulsio
Publikováno v:
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 57(6)
The interstrain differences in performance of C57BL/6J, BALB/c and DBA/2J male mice in two cognitive tasks were found. Mice C57BL/6J showed good learning ability and preservation of memory traces tested 10 days after performance in a simplified versi
Publikováno v:
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 57(5)
Genotype-dependent behavioral effects were demonstrated in BALB/c, C57BL/6J [Russian character: see text] DBA/2J mice after injections of nootropic drug Noopept. In an elevated plus maze, drug administration induced an increase in the number of enter
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 69(4)
The influence of noopept (N-phenylacetyl-L-prolylglycine ethyl ester, GVS-111) on the extent of ischemic cortical stroke was investigated in experiments on white mongrel male rats with ischemia induced by a combination of the middle cerebral artery o
Autor:
R U, Ostrovskaia
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 66(2)
Although the modern concept of neuroprotection has been formulated quite recently, the basis of this approach was laid about four decades ago when Zakusov initiated the study of mechanisms involved in the neuroprotector action of GABA shunt metabolit
Publikováno v:
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 51(2)
Male outbred rats were trained for step-through avoidance in different experimental conditions: 1) in a two-compartment chamber with a small dark compartment and a chamber with illuminated suspended platform; 2) with or without acquaintance with expe
Autor:
T A, Voronina, G M, Molodavkin, G G, Borlikova, R U, Ostrovskaia, N A, Tushmalova, G G, Naznamov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 63(2)
The effect of piracetam at various doses on the behavioral and electrophysiological characteristics was studied, including the development of passive and active avoidance conditional reflexes in rats, their behavior in conflict situations, and the tr