Zobrazeno 1 - 10
of 2 015
pro vyhledávání: '"R Testa"'
Autor:
Rafael R. Testa
Publikováno v:
Principia: An International Journal of Epistemology, Vol 28, Iss 1 (2024)
Belief Revision studies how rational agents change their beliefs in response to new information. The main objective of the works in this area is modelling these dynamics by defining some formal operators of change. This paper is an overview on the AG
Externí odkaz:
https://doaj.org/article/1e6c8707eaaf4c28aa522716d7adb73c
Autor:
John J. Krais, David J. Glass, Ilse Chudoba, Yifan Wang, Wanjuan Feng, Dennis Simpson, Pooja Patel, Zemin Liu, Ryan Neumann-Domer, Robert G. Betsch, Andrea J. Bernhardy, Alice M. Bradbury, Jason Conger, Wei-Ting Yueh, Joseph Nacson, Richard T. Pomerantz, Gaorav P. Gupta, Joseph R. Testa, Neil Johnson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Homologous recombination (HR)-deficiency induces a dependency on DNA polymerase theta (Polθ/Polq)-mediated end joining, and Polθ inhibitors (Polθi) are in development for cancer therapy. BRCA1 and BRCA2 deficient cells are thought to be s
Externí odkaz:
https://doaj.org/article/1134d3c423c24ee9b10823404374aee9
Autor:
Yavuz Sahin, Jianming Pei, Don A. Baldwin, Nashwa Mansoor, Lori Koslosky, Peter Abdelmessieh, Y. Lynn Wang, Reza Nejati, Joseph. R. Testa
Publikováno v:
Leukemia Research Reports, Vol 21, Iss , Pp 100465- (2024)
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy associated with various combinations of gene mutations, epigenetic abnormalities, and chromosome rearrangement-related gene fusions. Despite the significant degree of heterogene
Externí odkaz:
https://doaj.org/article/f0c3cc23a9b1481eaa5a4ec667934ac3
Autor:
Yavuz Sahin, Y. Lynn Wang, Jianming Pei, Nashwa Mansoor, Michael Styler, Joseph R. Testa, Reza Nejati
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 305 (2023)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with an aggressive clinical course and poor prognosis. The genetic abnormalities in BPDCN are heterogeneous; therefore, its molecular pathogenesis and the prognosti
Externí odkaz:
https://doaj.org/article/a79605f3e0f244698ce199c1312c6701
Autor:
Reza Nejati, Ryan Neumann-Domer, Zemin Liu, Lori Koslosky, Erin Neumann-Domer, Jianming Pei, Y. Lynn Wang, Joseph R. Testa
Publikováno v:
Leukemia Research Reports, Vol 20, Iss , Pp 100387- (2023)
We describe genomic findings in an AML case with isochromosome 7p, i(7)(p10), in which SNP array analysis uncovered an additional 7.07-Mb 20q deletion not detected by karyotyping. Several AML cases with i(7)(p10) as an isolated cytogenetic finding ha
Externí odkaz:
https://doaj.org/article/983bc9414f3c41d99a042aecf066b7b8
Autor:
Lauren E. Langbein, Eleonora Sementino, Zhijiu Zhong, Wei Jiang, Li Li, Joseph R. Testa, Haifeng Yang
Publikováno v:
Data in Brief, Vol 45, Iss , Pp 108743- (2022)
The data presented in this article are companion materials to our manuscript titled “BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma” (Langbein et al., 2022), where we investigate
Externí odkaz:
https://doaj.org/article/401d103111d7436ca5f17818e3dac68f
Autor:
Weijia Cai, Liya Su, Lili Liao, Zongzhi Z. Liu, Lauren Langbein, Essel Dulaimi, Joseph R. Testa, Robert G. Uzzo, Zhijiu Zhong, Wei Jiang, Qin Yan, Qing Zhang, Haifeng Yang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Acetylation of p53 is critical for its transcriptional activity and its tumour suppressive function. Here, the authors show that PBRM1 is a reader protein for p53′s C-terminal domain acetylation on lysine 382 through its bromodomain 4 and that muta
Externí odkaz:
https://doaj.org/article/4c56454ffebd47ce98598764f25ff35c
Autor:
Irina P. Panyushkina, Steven W. Leavitt, David M. Meko, Bryan A. Black, A. J. Timothy Jull, Peter Van de Water, Joe Squire, Nicholas R. Testa
Publikováno v:
Forests, Vol 13, Iss 12, p 2161 (2022)
Proxy records from the late Quaternary help in understanding climate variability on extended time scales. An ancient landslide deposit in Oregon U.S.A. preserved large logs from Douglas fir trees (Pseudotsuga menziesii (Mirb.) Franco) and afforded an
Externí odkaz:
https://doaj.org/article/dddaac86bd7e434ba86528afaf0b0806
Autor:
Ralph A. Pietrofesa, Shampa Chatterjee, Yuwaraj Kadariya, Joseph R. Testa, Steven M. Albelda, Melpo Christofidou-Solomidou
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10085 (2022)
Although alveolar macrophages play a critical role in malignant transformation of mesothelial cells following asbestos exposure, inflammatory and oxidative processes continue to occur in the mesothelial cells lining the pleura that may contribute to
Externí odkaz:
https://doaj.org/article/4f773da28553445c99bf56a6aab37cf7
Autor:
RAFAEL R. TESTA
Publikováno v:
Manuscrito, Vol 42, Iss 1, Pp 219-228 (2019)
Abstract In this review I briefly analyse the main elements of each chapter of the book centred in the general areas of logic, epistemology, philosophy and history of science. Most of them are developed around a fine-grained investigation on the prin
Externí odkaz:
https://doaj.org/article/2bf171d279b0429a8025b953da6eb4c3