Zobrazeno 1 - 2
of 2
pro vyhledávání: '"R T Hagelstrom"'
Autor:
Seungchan Kim, Raoul Tibes, Thomas C. Shea, Scott Mohrland, N. Frazer, Christian Beaudry, R. T. Hagelstrom, Reynaldo Garcia, John D. Carpten, James M Bogenberger, Katrina Schroeder, Kevin T. McDonagh, D. D. Von Hoff, Viji Shanmugam, D. Bassett, Lazaros J. Lekakis
Publikováno v:
Investigational new drugs. 33(2)
Inhibiting survivin and Cdc2 (CDK1) has preclinical anti-leukemic activity. Terameprocol is a small molecule survivin and Cdc2/CDK1 inhibitor that was studied in a Phase I dose-escalation trial. Sixteen patients with advanced acute myeloid leukemia (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82585124140d84fb8b61b4eb7592cf3b
https://pubmed.ncbi.nlm.nih.gov/25523151
https://pubmed.ncbi.nlm.nih.gov/25523151
Autor:
E H Goodwin, R T Hagelstrom, Susan M. Bailey, A J Williams, Lila Ramaiah, C Desaintes, K F Askin, Robert L. Ullrich
Publikováno v:
Oncogene. 27(53)
The phenomenon by which irradiated cells influence non-irradiated neighboring cells, referred to as the bystander effect (BSE), is not well understood in terms of the underlying pathways involved. We sought to enlighten connections between DNA damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6def58acbe8f6f142b246b638780cf61
https://pubmed.ncbi.nlm.nih.gov/18679419
https://pubmed.ncbi.nlm.nih.gov/18679419