Zobrazeno 1 - 10
of 75
pro vyhledávání: '"R T Gentry"'
Autor:
R. Sharma, R T Gentry, I Amir, Risto O. Roine, Enrique Baraona, Charles S. Lieber, Z. W. Chayes
Publikováno v:
Life Sciences. 65:2505-2512
Aspirin increases blood alcohol levels after post-prandial alcohol consumption in men. This was attributed to a decrease in first pass metabolism secondary to inhibition of gastric alcohol dehydrogenase. Since accelerated gastric emptying, decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba6feb20d67a23ec2777f47159249ce
https://doi.org/10.1016/s0024-3205(99)00517-2
https://doi.org/10.1016/s0024-3205(99)00517-2
Autor:
S. A. A. Mirmiran-Yazdy, R. T. Gentry, R. J. Greenstein, Ki M. Mak, P S Haber, Charles S. Lieber
Publikováno v:
Gastroenterology. 111:863-870
BACKGROUND & AIMS: The bioavailability of orally administered alcohol is incomplete, indicating first-pass metabolism. There is debate regarding the site of first-pass metabolism and specifically whether the stomach has the metabolic capacity to acco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b6666d8791f1d426188839df0a2415
https://doi.org/10.1016/s0016-5085(96)70054-9
https://doi.org/10.1016/s0016-5085(96)70054-9
Publikováno v:
Digestive Diseases and Sciences. 40:2091-2097
To determine whether the first-pass metabolism (FPM) of orally consumed alcohol varies with the time of day, 12 healthy male subjects were tested with both oral and intravenous alcohol (0.3 g/kg), in the morning and evening, always 1 hr after the sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71b1d750067ffa55d9674a4552ec25c
https://doi.org/10.1007/bf02208989
https://doi.org/10.1007/bf02208989
Publikováno v:
Digestive Diseases. 12:351-367
In most individuals, only part of the imbibed alcohol reaches the systemic blood. With doses relevant to social drinking, this is due mainly to gastric first-pass metabolism of alcohol, which acts as a barrier against toxic alcohol blood levels. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec89c7930156e4dacae12e5e0cb843c6
https://doi.org/10.1159/000171470
https://doi.org/10.1159/000171470
Publikováno v:
Alcoholism: Clinical and Experimental Research. 15:734-738
The effect of the concentration of ingested ethanol on the resulting blood alcohol concentrations (BAC) was tested in both humans and rats. In humans, when 0.3 g/kg body weight ethanol was ingested postprandially, the mean area under the blood alcoho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2875af0be2a04697165f812f0e69b387
https://doi.org/10.1111/j.1530-0277.1991.tb00589.x
https://doi.org/10.1111/j.1530-0277.1991.tb00589.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 17:709-711
To determine whether blood alcohol concentrations achieved by ingestion of various alcoholic beverages differ as a function of prandial state, healthy male volunteers, aged 24 to 48 years, were given the same amount of alcohol (0.3 g/kg) as different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e50144120b2fc7c72c024869b540b25
https://doi.org/10.1111/j.1530-0277.1993.tb00824.x
https://doi.org/10.1111/j.1530-0277.1993.tb00824.x
Autor:
R T, Gentry
Publikováno v:
Alcoholism, clinical and experimental research. 24(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::664e23f3e16a3d3a0714315c7b50c415
https://pubmed.ncbi.nlm.nih.gov/10798565
https://pubmed.ncbi.nlm.nih.gov/10798565
Publikováno v:
The Journal of laboratory and clinical medicine. 123(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5d632c42bd1d5682344ef8363255ec7
https://pubmed.ncbi.nlm.nih.gov/8288957
https://pubmed.ncbi.nlm.nih.gov/8288957
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. 2
The human stomach has both low and high K(m) ADH isozymes, resulting in significant ethanol metabolism in gastric cells in vitro, and decreased bioavailability of ethanol (first pass metabolism: FPM) in vivo. Intraduodenal or intraportal infusion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1372c3db1b4cfcc4dc840faf0ca58ba
https://pubmed.ncbi.nlm.nih.gov/8974331
https://pubmed.ncbi.nlm.nih.gov/8974331
Publikováno v:
JAMA. 267(1)
To determine whether the H2-receptor antagonist, ranitidine, which is a potent inhibitor of gastric alcohol dehydrogenase activity in vitro, increases the bioavailability of orally administered ethanol (0.3 g/kg of body weight) and to compare the res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::993afaafc61ec486d6231b42b21cb8a2
https://pubmed.ncbi.nlm.nih.gov/1349359
https://pubmed.ncbi.nlm.nih.gov/1349359