Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R T, Reilly"'
Publikováno v:
Biochemistry. 32:9888-9895
Traditional fluorine-19 nuclear magnetic resonance (19F NMR) studies of thymidylate synthase (TS) have utilized the fluorine substituent of 5-fluorodeoxyuridine 5'-monophosphate (FdUMP), a mechanism-based inhibitor of the enzyme, in complexes with va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef72a3f467b9385255637046dafcd194
https://doi.org/10.1021/bi00089a003
https://doi.org/10.1021/bi00089a003
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 2(1)
Recent advances in our understanding of immune function with regard to the generation of a potent antitumor response have resulted in a renewed interest in cancer vaccines and point to a role for immunotherapy in the treatment of cancer. Currently, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d954df45060b436f672cfa8471993e18
https://pubmed.ncbi.nlm.nih.gov/11527005
https://pubmed.ncbi.nlm.nih.gov/11527005
Publikováno v:
Current opinion in molecular therapeutics. 3(1)
Cancer vaccines are on the threshold of taking their place alongside the more traditional cancer treatment modalities of surgery, radiation therapy and chemotherapy. The toxicology and immunopharmacology of therapeutic cancer vaccines, particularly t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a562f86e9011d208649c7320d706e406
https://pubmed.ncbi.nlm.nih.gov/11249735
https://pubmed.ncbi.nlm.nih.gov/11249735
Autor:
R T, Reilly, J P, Machiels, L A, Emens, A M, Ercolini, F I, Okoye, R Y, Lei, D, Weintraub, E M, Jaffee
Publikováno v:
Cancer Research, Vol. 61, no.3, p. 880-883 (2001)
HER-2/neu (neu) transgenic mice (neu-N mice), which express the nontransforming rat proto-oncogene, demonstrate immunological tolerance to neu that is similar to what is encountered in patients with neu-expressing breast cancer. We have shown previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::64bd24b8fe3c31548ca433cfffe0cdde
https://hdl.handle.net/2078.1/212974
https://hdl.handle.net/2078.1/212974
Autor:
J P, Machiels, R T, Reilly, L A, Emens, A M, Ercolini, R Y, Lei, D, Weintraub, F I, Okoye, E M, Jaffee
Publikováno v:
Cancer Research, Vol. 61, no.9, p. 3689-3697 (2001)
Tumor-specific immune tolerance limits the effectiveness of cancer vaccines. In addition, tumor vaccines alone have a limited potential for the treatment of measurable tumor burdens. This highlights the importance of identifying more potent cancer va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::98f72c893e4434dbe5303bd013cc256f
https://hdl.handle.net/2078.1/212972
https://hdl.handle.net/2078.1/212972
Publikováno v:
Molecular pharmacology. 48(1)
Thymidylate synthase (TS) is a homodimeric enzyme that catalyzes the reductive methylation of dUMP by N5,N10-methylene-5,6,7,8-tetrahydrofolic acid, to form dTMP. Inhibition of TS by the dUMP analog 5-fluoro-dUMP (FdUMP) occurs through the formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8776ec64829cf640ff9cd7f2237ba94a
https://pubmed.ncbi.nlm.nih.gov/7623777
https://pubmed.ncbi.nlm.nih.gov/7623777
Autor:
R. T. Reilly
Publikováno v:
Journal - American Water Works Association. 28:896-907
The development existing today in the territory bordering on Lake Michigan has taken place in the short span of a little more than 100 years. Other civilizations ripened and matured by centuries of experience still lack much in the way of wholesome w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::651aa2fb919a0fc5dba23d42aae51c71
https://doi.org/10.1002/j.1551-8833.1936.tb19479.x
https://doi.org/10.1002/j.1551-8833.1936.tb19479.x
Publikováno v:
American journal of hospital pharmacy. 42(2)
Pharmacy department costs for preparing and administering intermittent i.v. drug doses using a piggyback bottle system and a syringe pump system were predicted and compared. Centralized i.v. admixture service personnel time for preparation of small-v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4625d7e7da82f0779cb4f136af0dd664
https://pubmed.ncbi.nlm.nih.gov/3976678
https://pubmed.ncbi.nlm.nih.gov/3976678
Publikováno v:
American journal of hospital pharmacy. 43(9)
Attempts to control costs associated with antimicrobial therapy and surgical prophylaxis with injectable cephalosporins in a 335-bed, acute-care, county teaching hospital are described. An ABC analysis of our pharmacy inventory revealed that 11.8% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39c2d983b8ea68a0f87870ce2ec52db5
https://pubmed.ncbi.nlm.nih.gov/3766571
https://pubmed.ncbi.nlm.nih.gov/3766571