Zobrazeno 1 - 10
of 342
pro vyhledávání: '"R T, Prehn"'
Autor:
R T, Prehn
Publikováno v:
Cancer research. 59(17)
It has been widely suggested that elevated androgen levels may be critically involved in the genesis of prostate cancer. Despite the dependency of the normal prostate and of most prostatic cancers upon androgens and the fact that tumors can be produc
Autor:
R T, Prehn
Publikováno v:
Folia biologica. 43(4)
Autor:
R T, Prehn
Publikováno v:
Cancer research. 56(5)
Partial regression in cutaneous malignant melanoma has been reported by a number of observers, albeit not all, to be associated with a relatively poor prognosis; in contrast, a keratoacanthoma, which eventually regresses, does not metastasize. The Ha
Autor:
R T, Prehn, L M, Prehn
Publikováno v:
Medicina. 56
A moderate antitumor immune reaction is optimal for tumor growth and most (perhaps all) untransplanted tumors, rather than being inhibited, are probably dependent, at least early in their progression, upon the immune reaction. Some tumors, as for exa
Autor:
R T, Prehn
Publikováno v:
Cancer research. 54(20)
Despite the plethora of "oncogenes" and "tumor suppressor genes," the hypothesis that cancer is usually the result of genomic mutations may be wrong. We should at least examine the alternative hypothesis, for which there is considerable evidence, tha
Autor:
R T, Prehn
Publikováno v:
Cancer research. 54(4)
The accumulated literature suggests that altering the immune capacities of animals or humans seldom has detectable effects on tumor incidence nor, it seems, does the growth of an untransplanted tumor, either spontaneous or induced, immunize the host
Autor:
R T, Prehn
Publikováno v:
Cancer research. 53(14)
A second tumor inoculum is often inhibited in its growth by the presence in the recipient animal of an earlier implanted, growing tumor. The tumor resulting from the first inoculum may, paradoxically, continue to grow despite the simultaneous inhibit
Autor:
R T, Prehn
Publikováno v:
Cancer research. 52(3)
Both organ growth and tumor growth are dependent upon a biased ratio of cell births to cell deaths; this ratio is independent of the frequency of mitosis. Thus, so-called growth factors that affect only the frequency of mitosis are not really growth
Autor:
R T, Prehn
Publikováno v:
Cancer research. 51(1)
Evidence suggests that a tumor behaves, in its pattern of growth, like an integrated organ rather than a collection of independently growing cells. Tumor growth tends to slow progressively as size increases and to undergo compensatory growth after pa
Autor:
R. T. Prehn
Publikováno v:
Scandinavian journal of immunology. 32(3)
The demonstration of the existence of antigenic mimicry suggests that immunological tolerance to self antigens may be an insufficient basis for distinguishing self from non-self. However, some data suggest that even in the absence of tolerance most s