Zobrazeno 1 - 10
of 22
pro vyhledávání: '"R T, Moon"'
Autor:
J. Mathieu, D. Detraux, D. Kuppers, Y. Wang, C. Cavanaugh, S. Sidhu, S. Levy, A. M. Robitaille, A. Ferreccio, T. Bottorff, A. McAlister, L. Somasundaram, F. Artoni, S. Battle, R. D. Hawkins, R. T. Moon, C. B. Ware, P. J. Paddison, H. Ruohola-Baker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The pathways involved in exit from pluripotency in human embryonic stem cells are poorly understood. Here, the authors performed a CRISPR-based screen to identify genes that promote exit from naïve pluripotency and find a role for folliculin (FLCN)
Externí odkaz:
https://doaj.org/article/d50b9ac4e8764f89b3e5badb92229b82
Autor:
K, Brown, P, Yang, D, Salvador, R, Kulikauskas, H, Ruohola-Baker, A M, Robitaille, A J, Chien, R T, Moon, V, Sherwood
Publikováno v:
Oncogene
Aberrant regulation of WNT/β-catenin signaling has a crucial role in the onset and progression of cancers, where the effects are not always predictable depending on tumor context. In melanoma, for example, models of the disease predict differing eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07293c0b09ecda6c60f2680d2a18a0c5
https://pubmed.ncbi.nlm.nih.gov/28092677
https://pubmed.ncbi.nlm.nih.gov/28092677
Autor:
J D, Berndt, R T, Moon
Publikováno v:
Science (New York, N.Y.). 339(6126)
Developmental signals such as Wnts are often presented to cells in an oriented manner. To examine the consequences of local Wnt signaling, we immobilized Wnt proteins on beads and introduced them to embryonic stem cells in culture. At the single-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22b2459442d00150d159cfdd740112d8
https://pubmed.ncbi.nlm.nih.gov/23520113
https://pubmed.ncbi.nlm.nih.gov/23520113
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 22(8)
Neural crest cells are multipotent progenitors, capable of producing diverse cell types upon differentiation. Recent studies have identified significant heterogeneity in both the fates produced and genes expressed by different premigratory crest cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d30e0ec14910d70cee365d9893eb62a7
https://pubmed.ncbi.nlm.nih.gov/10918301
https://pubmed.ncbi.nlm.nih.gov/10918301
Publikováno v:
Trends in genetics : TIG. 16(7)
Members of the vertebrate Wnt family have been subdivided into two functional classes according to their biological activities. Some Wnts signal through the canonical Wnt-1/wingless pathway by stabilizing cytoplasmic beta-catenin. By contrast other W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de15d7af18c61bdf8c36ac3438eae408
https://pubmed.ncbi.nlm.nih.gov/10858654
https://pubmed.ncbi.nlm.nih.gov/10858654
Publikováno v:
Molecular marine biology and biotechnology. 7(4)
We describe a simple method for producing androgenetic haploid embryos in zebrafish. Mature eggs are expressed, and the maternal genome is inactivated by irradiation with short-wave ultraviolet light prior to in vitro fertilization. We demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0daef9c3f97006476cedb15493e9d168
https://pubmed.ncbi.nlm.nih.gov/9892723
https://pubmed.ncbi.nlm.nih.gov/9892723
Autor:
R T, Moon, D, Kimelman
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 20(7)
After fertilization of Xenopus eggs, the cortex rotates relative to the cytoplasm, resulting in the formation of a cytoplasmic and transplantable dorsal-determining activity opposite the sperm entry point. This activity induces the dorsal expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d70ff3c6cc709195fe95505bba64f43
https://pubmed.ncbi.nlm.nih.gov/9723002
https://pubmed.ncbi.nlm.nih.gov/9723002
Autor:
R T, Moon, J L, Christian, R M, Campbell, L L, McGrew, A A, DeMarais, M, Torres, C J, Lai, D J, Olson, G M, Kelly
Publikováno v:
Development (Cambridge, England). Supplement.
We review evidence that Xenopus Wnts (Xwnts) have activities consistent with their hypothesized roles as secreted signalling factors involved in multiple developmental processes. Transient misexpression of different Xwnts has distinct effects upon ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ab6ddc63b1d0516763263320cc557a4
https://pubmed.ncbi.nlm.nih.gov/8049491
https://pubmed.ncbi.nlm.nih.gov/8049491
Autor:
R A Stambuk, R T Moon
Publikováno v:
The Biochemical journal. 287
The poly(A)(+)-binding protein (PABP) is a highly conserved protein that binds to the poly(A)+ tail of mRNAs. PABP has been shown to regulate message stability and translational efficiency, yet the mechanisms remain unknown. To facilitate further dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53ee40e6cf25efcfaaee36c44d72c83
https://pubmed.ncbi.nlm.nih.gov/1280105
https://pubmed.ncbi.nlm.nih.gov/1280105
Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family
Autor:
S L, Wolda, R T, Moon
Publikováno v:
Oncogene. 7(10)
Degenerate oligonucleotide primers encoding highly conserved regions of Wnt-related proteins were used with the polymerase chain reaction (PCR) to amplify cDNA derived from Xenopus laevis embryos. cDNA sequences partially encoding seven additional me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18ea8121af3e25d722dcba70ebac0980
https://pubmed.ncbi.nlm.nih.gov/1408135
https://pubmed.ncbi.nlm.nih.gov/1408135