Zobrazeno 1 - 10
of 75
pro vyhledávání: '"R T, Kubo"'
Autor:
S, Southwood, J, Sidney, A, Kondo, M F, del Guercio, E, Appella, S, Hoffman, R T, Kubo, R W, Chesnut, H M, Grey, A, Sette
Publikováno v:
The Journal of Immunology. 160:3363-3373
The peptide binding specificities of HLA-DRB1*0401, DRB1*0101, and DRB1*0701 have been analyzed by the use of large collections of synthetic peptides corresponding to naturally occurring sequences. The results demonstrated that nearly all peptides bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddfe3e7abeda2ba6d12dd4868eef3b18
https://doi.org/10.4049/jimmunol.160.7.3363
https://doi.org/10.4049/jimmunol.160.7.3363
Autor:
J Alexander, C Oseroff, J Sidney, P Wentworth, E Keogh, G Hermanson, F V Chisari, R T Kubo, H M Grey, A Sette
Publikováno v:
The Journal of Immunology. 159:4753-4761
Transgenic mice expressing chimeric human (alpha1 and alpha2 HLA-A11 domains) and murine (alpha3, transmembrane, and cytoplasmic H-2Kb domains) class I molecules were derived. These mice were used as a model system to study the immunogenicity of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ac406e2d681bfec6899c12a21eee72c
https://doi.org/10.4049/jimmunol.159.10.4753
https://doi.org/10.4049/jimmunol.159.10.4753
Publikováno v:
The Journal of Immunology. 157:3480-3490
The HLA-B7-like binding supertype includes several different HLA-B molecules. Herein, the primary and secondary anchor specificities of the five most common HLA-B7-like molecules (B*0702, B*3501, B51, B*5301, and B*5401) were defined by the use of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d1ae03f6af2903cb580bf10da8a0138
https://doi.org/10.4049/jimmunol.157.8.3480
https://doi.org/10.4049/jimmunol.157.8.3480
Autor:
A Kondo, J Sidney, S Southwood, M F del Guercio, E Appella, H Sakamoto, E Celis, H M Grey, R W Chesnut, R T Kubo, A Sette
Publikováno v:
The Journal of Immunology. 155:4307-4312
The binding capacity of large sets of peptides corresponding to naturally occurring sequences and carrying previously defined A24-specific motifs was analyzed. It was found that only a minority (9-25%) of the motif-carrying peptides bound the relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5e23b0000fd5b235ef3f8355c9fe961
https://doi.org/10.4049/jimmunol.155.9.4307
https://doi.org/10.4049/jimmunol.155.9.4307
Publikováno v:
The Journal of Immunology. 154:685-693
Direct MHC binding assays with radiolabeled peptides and HLA class I-expressing mammalian cells such as EBV-transformed B cell lines and PHA-activated blasts have been developed. Significant binding of the radiolabeled probe could be obtained if the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7941c2620e45e00a248984d8a7b0b90
https://doi.org/10.4049/jimmunol.154.2.685
https://doi.org/10.4049/jimmunol.154.2.685
Publikováno v:
The Journal of Immunology. 153:1563-1580
The zeta subunit of the TCR complex targets receptor surface expression, is phosphorylated on tyrosine residues upon T cell activation, and is implicated in signal transduction after TCR ligation. Here we show that, although intrathymic expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::341e5d75029e4bf953b6f83b66aa9905
https://doi.org/10.4049/jimmunol.153.4.1563
https://doi.org/10.4049/jimmunol.153.4.1563
Autor:
R T Kubo, A Sette, H M Grey, E Appella, K Sakaguchi, N Z Zhu, D Arnott, N Sherman, J Shabanowitz, H Michel
Publikováno v:
The Journal of Immunology. 152:3913-3924
Allele-specific motifs for the human MHC class I molecules, HLA-A1, A3, A11, and A24 were characterized by three complementary approaches. First, amino acid sequence analysis of acid eluted peptide pools from affinity purified class I molecules defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b751a94532c4d7e976f9de9f0a64e697
https://doi.org/10.4049/jimmunol.152.8.3913
https://doi.org/10.4049/jimmunol.152.8.3913
Publikováno v:
The Journal of Immunology. 151:6822-6832
Mixed isotype MHC class II molecules (E alpha dA beta d) occur at extremely low levels on the surface of normal mouse B cells and macrophages, as determined by surface staining with an E alpha dA beta d-specific hamster mAb, H71-258.41. The surface l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7af7640b1a0f7dcaf38652620dc87a7
https://doi.org/10.4049/jimmunol.151.12.6822
https://doi.org/10.4049/jimmunol.151.12.6822
Publikováno v:
The Journal of Immunology. 146:3340-3346
Some thymocytes, upon activation via the TCR complex in vitro, undergo apoptotic cell death. In this report, we examine the cell death induced in the thymus after administration of anti-CD3 or anti-TCR antibodies. We found that shortly after antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce6c319f81f6f7d51a916b9e85b152f3
https://doi.org/10.4049/jimmunol.146.10.3340
https://doi.org/10.4049/jimmunol.146.10.3340
Publikováno v:
The Journal of Experimental Medicine
Superantigen bound to major histocompatibility complex (MHC) products have been shown to stimulate T cells in a V beta-specific manner. Mouse T cells bearing V beta 8.1 usually respond to the self superantigen, Mls-1a, whereas T cells bearing V beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5041e37c4df561ed6c47fa0de3ec4449
http://europepmc.org/articles/PMC2118855
http://europepmc.org/articles/PMC2118855