Zobrazeno 1 - 4
of 4
pro vyhledávání: '"R T, Bilinski"'
Autor:
M J, Weyant, A M, Carothers, N N, Mahmoud, H L, Bradlow, H, Remotti, R T, Bilinski, M M, Bertagnolli
Publikováno v:
Cancer research. 61(6)
Menopausal hormone replacement therapy has been widely used to alleviate the symptoms of menopause and to decrease the detrimental effects of ovarian hormone loss on bone density and cardiovascular health. Multiple studies of colorectal cancer epidem
Publikováno v:
Cancer research. 59(2)
The adenomatous polyposis coli (APC) gene product mediates coordinated cell growth in the intestinal mucosa. In humans, germ-line mutations of APC are associated with colorectal carcinogenesis, a process that varies in severity depending on the lengt
Autor:
N N, Mahmoud, A J, Dannenberg, J, Mestre, R T, Bilinski, M R, Churchill, C, Martucci, H, Newmark, M M, Bertagnolli
Publikováno v:
Surgery. 124(2)
Both human and murine studies suggest that anti-inflammatory drugs prevent intestinal neoplasia. The purpose of this study was to investigate the role of aspirin as a chemopreventive agent for colorectal cancer.We administered aspirin to the Min/+ mo
Publikováno v:
Cancer research. 57(22)
Apc-associated intestinal tumor formation appears to require functional loss of both Apc alleles. Apc has, therefore, been classified as a tumor suppressor gene. Loss of APC protein function results in increased intracellular beta-catenin, a molecule