Zobrazeno 1 - 10
of 49
pro vyhledávání: '"R Spycher"'
Autor:
Philipp R. Spycher, Susanna M. Früh, Ingmar Schoen, Ralf Jungmann, Sebastian Lickert, Viola Vogel, Ulf Matti, Marina Rubini, Jonas Ries, Thomas Schlichthaerle
Publikováno v:
ACS Nano, 15 (7)
The precise spatial localization of proteins in situ by super-resolution microscopy (SRM) demands their targeted labeling. Positioning reporter molecules as close as possible to the target remains a challenge in primary cells or tissues from patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b0d6632614e3e1b41c5aef8a843012
https://hdl.handle.net/20.500.11850/492108
https://hdl.handle.net/20.500.11850/492108
Autor:
Susanna M, Früh, Ulf, Matti, Philipp R, Spycher, Marina, Rubini, Sebastian, Lickert, Thomas, Schlichthaerle, Ralf, Jungmann, Viola, Vogel, Jonas, Ries, Ingmar, Schoen
Publikováno v:
ACS Nano
The precise spatial localization of proteins in situ by super-resolution microscopy (SRM) demands their targeted labeling. Positioning reporter molecules as close as possible to the target remains a challenge in primary cells or tissues from patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::046655d0850149f698a24c1c35dad44a
https://pubmed.ncbi.nlm.nih.gov/34184536
https://pubmed.ncbi.nlm.nih.gov/34184536
Autor:
Philipp R. Spycher, Philipp Probst, Ramona Stark, Dragan Grabulovski, Romain Bertrand, Roger Santimaria, Isabella Attinger-Toller
Publikováno v:
Cancer Research. 81:1842-1842
Araris' site-specific conjugation technology is improving the safety and efficacy of ADCs without antibody engineering. Our technology is using transglutaminase for site-specific enzymatic payload conjugation to ‘off-the-shelf' antibodies, i.e., wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb3a33ab6f583d34f86e82768e0d62cc
https://doi.org/10.1158/1538-7445.am2021-1842
https://doi.org/10.1158/1538-7445.am2021-1842
Autor:
Mikael Jensen, Matthias Gunzer, Philipp R. Spycher, Djamschid Solouk-Saran, Christopher R. Thornton, Mike Hasenberg, Martin Eichner, Bernd J. Pichler, Lauren S. Ryder, Anna-Maria Rolle, Stefan Wiehr, Jesper Fonslet, Adrien Dubois, Roger Schibli, Frédéric Boschetti, Genna Davies, Franck Denat, Claudia Schillinger, Andreas Maurer, Juliane Weski
Publikováno v:
Theranostics
Theranostics, Ivyspring International Publisher, 2017, 7 (14), pp.3398-3414. 〈http://www.thno.org/v07p3398.htm〉. 〈10.7150/thno.20919〉
Davies, G, Rolle, A-M, Maurer, A, Spycher, P R, Schillinger, C, Solouk-Saran, D, Hasenberg, M, Weski, J, Fonslet, J, Dubois, A, Boschetti, F, Denat, F, Gunzer, M, Eichner, M, Ryder, L S, Jensen, M, Schibli, R, Pichler, B J, Wiehr, S & Thornton, C R 2017, ' Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo ', Theranostics, vol. 7, no. 14, pp. 3398-3414 . https://doi.org/10.7150/thno.20919
Theranostics, 7 (14)
Theranostics, Ivyspring International Publisher, 2017, 7 (14), pp.3398-3414. ⟨10.7150/thno.20919⟩
Theranostics, Ivyspring International Publisher, 2017, 7 (14), pp.3398-3414. 〈http://www.thno.org/v07p3398.htm〉. 〈10.7150/thno.20919〉
Davies, G, Rolle, A-M, Maurer, A, Spycher, P R, Schillinger, C, Solouk-Saran, D, Hasenberg, M, Weski, J, Fonslet, J, Dubois, A, Boschetti, F, Denat, F, Gunzer, M, Eichner, M, Ryder, L S, Jensen, M, Schibli, R, Pichler, B J, Wiehr, S & Thornton, C R 2017, ' Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo ', Theranostics, vol. 7, no. 14, pp. 3398-3414 . https://doi.org/10.7150/thno.20919
Theranostics, 7 (14)
Theranostics, Ivyspring International Publisher, 2017, 7 (14), pp.3398-3414. ⟨10.7150/thno.20919⟩
Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy or bone marrow transplant patients caused by the ubiquitous environmental fungus Aspergillus fumigatus. Current diagnostic tests for the disease lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11534a76147f07784219110c83f668b7
http://europepmc.org/articles/PMC5596432
http://europepmc.org/articles/PMC5596432
Autor:
Matthias Gunzer, Andreas Maurer, Johannes Schwenck, Stefan Wiehr, Christopher R. Thornton, Roger Schibli, H Henneberg, Frédéric Boschetti, Bernd J. Pichler, Gerald Reischl, Anna-Maria Wild, Jöri Elias Wehrmüller, Nicolas Beziere, Genna Davies, Philipp R. Spycher
Publikováno v:
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d83210e112bd6fd0b72f20e24ab192
https://doi.org/10.1055/s-0039-1683488
https://doi.org/10.1055/s-0039-1683488
Publikováno v:
Chembiochem : a European journal of chemical biology
Antibody-like proteins selected from discovery platforms are preferentially functionalized by site-specific modification as this approach preserves the binding abilities and allows a side-by-side comparison of multiple conjugates. Here we present an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5372ba8e097f4bc0fe56c2a4f91f25ff
https://doi.org/10.1002/cbic.201500009
https://doi.org/10.1002/cbic.201500009
Autor:
Alain Blanc, Roger Schibli, Jöri Elias Wehrmüller, Andreas Ritler, Daniel Messmer, Olivier Kreis, Martin Béhé, David Hurwitz, Peter Walde, Andreas Küchler, Christian A. Amann, Philipp R. Spycher
Publikováno v:
ChemBioChem, 18 (19)
ChemBioChem, 18 (19)
ISSN:1439-4227
ISSN:1439-7633
ISSN:1439-4227
ISSN:1439-7633
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39bf11f90fee6a0ee4f0c1ff27503a4
https://hdl.handle.net/20.500.11850/280202
https://hdl.handle.net/20.500.11850/280202
Autor:
Susanna M. Früh, Melanie A. Burkhardt, Maria Mitsi, Philipp R. Spycher, Ingmar Schoen, Viola Vogel
Publikováno v:
ChemBioChem
A straightforward strategy is presented for the site-specific incorporation of fluorophores or reactive probes into the extracellular matrix (ECM) protein fibronectin (Fn) by using the enzyme-catalyzed transamidation by activated factor XIII. Charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c503cf08317d9a597b5dc3297809bd53
https://doi.org/10.1002/cbic.201402099
https://doi.org/10.1002/cbic.201402099
Autor:
Torsten Hechler, Andreas Pahl, Isabella Attinger-Toller, Julia Carina Frei, Michael Kulke, Martin Béhé, Roger Schibli, Dragan Grabulovski, Jöri Elias Wehrmüller, Philipp R. Spycher
Publikováno v:
Cancer Research. 79:LB-106
We introduce a novel and versatile ADC-linker technology that is based on site-specific enzymatic payload conjugation to ‘off-the-shelf’ antibodies, i.e., without the need to reduce or engineer the antibody. The functionalization takes place site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4330ff73dfb005f17c4ba9e04ee7fe93
https://doi.org/10.1158/1538-7445.am2019-lb-106
https://doi.org/10.1158/1538-7445.am2019-lb-106
Autor:
Christophe Combescure, R. Spycher, Jacques Fracheboud, Maximilien Catsiyannis, Bernard Hirschel
Publikováno v:
Schweizerische Ärztezeitung. 97
Wer jemanden uber seine HIV-Infektion tauscht und so zum ungeschutzten Geschlechtsverkehr verleitet und infiziert, macht sich strafbar. Aber wie ist diese Straftat rechtlich zu qualifizieren? Einfache oder schwere Korperverletzung? Ein solcher Fall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f600079ff7ec3cd60be45f4f5fa7549b
https://doi.org/10.4414/saez.2016.04309
https://doi.org/10.4414/saez.2016.04309