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Publikováno v:
Ultrasound. 20:41-48
Introduction Ultrasound-guided regional anaesthesia (UGRA) is being used increasingly in patients but varying patient characteristics make it difficult to visualize needles and spread of local anaesthetic fluid. Methods To evaluate the use of elastog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d19c70f8f6a436bc6019e78865c79bf3
https://doi.org/10.1258/ult.2011.011039
https://doi.org/10.1258/ult.2011.011039
Autor:
A R Soames, D R Camidge, P J Laud, A. Hughes, C J Sadler, K R Randall, Jayne Wright, Paul D. Smith, John R. Foster
Publikováno v:
British Journal of Cancer
We have demonstrated the feasibility of detecting and quantifying six cell-cycle-related nuclear markers (Ki67, pRb, p27, phospho-p27 (phosphorylated p27), phospho-pRb (phosphorylated pRb), phospho-HH3 (phosphorylated histone H3)) in plucked human sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb468b24f8d837c9d2d0a112e1b5069
https://doi.org/10.1038/sj.bjc.6602558
https://doi.org/10.1038/sj.bjc.6602558
Autor:
John Ashby, Hur Song Chang, Fei Ling Lim, Helen Tinwell, Ruth Stuckey, George Orphanides, Ian Kimber, Tracey Spurway, Tong Zhu, Anthony R. Soames, David J. Moore, Jonathan G. Moggs, Ian Pate, Richard A. Currie
Publikováno v:
Environmental Health Perspectives
A major challenge in the emerging field of toxicogenomics is to define the relationships between chemically induced changes in gene expression and alterations in conventional toxicologic parameters such as clinical chemistry and histopathology. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530efc47f1f6bea3e41d2d438033defc
https://doi.org/10.1289/ehp.7345
https://doi.org/10.1289/ehp.7345
Autor:
L. John R. Foster, Ian Kimber, Clifford R Elcombe, J. Odum, John Ashby, Anthony R. Soames, S.C. Hasmall, Susan Stone
Publikováno v:
Environmental Health Perspectives
We studied nine presumed nongenotoxic rodent carcinogens, as defined by the U.S. National Toxicology Program (NTP), to determine their ability to induce acute or subacute biochemical and tissue changes that may act as useful predictors of nongenotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6ab41d6e7009d7aaf92e49d9e7bab0
https://doi.org/10.1289/ehp.02110363
https://doi.org/10.1289/ehp.02110363
Publikováno v:
Journal of Applied Toxicology. 22:387-395
Sulphuric acid mists have been classified by the International Agency for Research on Cancer as being carcinogenic to humans based on epidemiological findings of respiratory tract tumours. To determine if early changes in the respiratory tract follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144fdc09e1eebac072eefb73539125e9
https://doi.org/10.1002/jat.875
https://doi.org/10.1002/jat.875
Publikováno v:
Toxicologic Pathology. 28:157-163
In 2 studies, a method of linear morphometry was applied to regulatory developmental neurotoxicity studies in the rat. The first study involved the development of the brain during postnatal days (PNDs) 7-63, and the second involved the effects of 8 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff914d6b469c22716f81e7afda8fe051
https://doi.org/10.1177/019262330002800120
https://doi.org/10.1177/019262330002800120
Publikováno v:
Environmental Health Perspectives
Administration of the phytoestrogen coumestrol to ovariectomized rats leads to increases in both wet and dry uterine weights in the absence of an increase in uterine DNA content, as reported by Markaverich et al. [Effects of Coumestrol on Estrogen Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a81654403ee44ce2dab88498ff11c84
https://doi.org/10.1289/ehp.99107819
https://doi.org/10.1289/ehp.99107819
Autor:
R. L. Joiner, John Ashby, Jeff Foster, Anthony R. Soames, J. Odum, J. P. Van Miller, I. T. G. Pyrah
Publikováno v:
Journal of Applied Toxicology. 19:367-378
An earlier report by Colerangle and Roy indicated that administration of p-nonylphenol (NP) to Noble rats, via subcutaneously implanted mini-pumps at estimated doses of 53.2 and 0.073 mg kg(-1) day(-1) for 11 days, led to proliferation of the mammary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e0a44f0ef441ed50bf0e72988bb969
https://doi.org/10.1002/(sici)1099-1263(199909/10)19:5<367::aid-jat593>3.0.co
https://doi.org/10.1002/(sici)1099-1263(199909/10)19:5<367::aid-jat593>3.0.co
Publikováno v:
Archives of Toxicology. 72:784-790
Nongenotoxic rodent hepatocarcinogens do not damage DNA but cause liver tumours in the rat and mouse, associated with the induction of hepatic DNA synthesis. Previously, we have demonstrated that nongenotoxic hepatocarcinogens such as phenobarbitone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e37693df47b93c4959571c37ea79879
https://doi.org/10.1007/s002040050574
https://doi.org/10.1007/s002040050574