Zobrazeno 1 - 10
of 270
pro vyhledávání: '"R Scott Hawley"'
Autor:
Youbin Xiang, Dai Tsuchiya, Fengli Guo, Jennifer Gardner, Scott McCroskey, Andrew Price, Eelco C Tromer, James R Walters, Cathleen M Lake, R Scott Hawley
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 5 (2023)
AbstractMeiosis is usually described as 4 essential and sequential processes: (1) homolog pairing; (2) synapsis, mediated by the synaptonemal complex; (3) crossing over; and (4) segregation. In this canonical model, the maturation of crossovers into
Externí odkaz:
https://doaj.org/article/d0d6221d5f60433298d0a371aead6329
Autor:
Danny E Miller, Ana P Dorador, Kelley Van Vaerenberghe, Angela Li, Emily K Grantham, Stefan Cerbin, Celeste Cummings, Marilyn Barragan, Rhonda R Egidy, Allison R Scott, Kate E Hall, Anoja Perera, William D Gilliland, R Scott Hawley, Justin P Blumenstiel
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010598 (2023)
Transposable elements (TE) are selfish genetic elements that can cause harmful mutations. In Drosophila, it has been estimated that half of all spontaneous visible marker phenotypes are mutations caused by TE insertions. Several factors likely limit
Externí odkaz:
https://doaj.org/article/0ab436fda324423bb41b77dd49c091fb
Autor:
Bernard Y Kim, Jeremy R Wang, Danny E Miller, Olga Barmina, Emily Delaney, Ammon Thompson, Aaron A Comeault, David Peede, Emmanuel RR D'Agostino, Julianne Pelaez, Jessica M Aguilar, Diler Haji, Teruyuki Matsunaga, Ellie Armstrong, Molly Zych, Yoshitaka Ogawa, Marina Stamenković-Radak, Mihailo Jelić, Marija Savić Veselinović, Marija Tanasković, Pavle Erić, Jian-Jun Gao, Takehiro K Katoh, Masanori J Toda, Hideaki Watabe, Masayoshi Watada, Jeremy S Davis, Leonie C Moyle, Giulia Manoli, Enrico Bertolini, Vladimír Košťál, R Scott Hawley, Aya Takahashi, Corbin D Jones, Donald K Price, Noah Whiteman, Artyom Kopp, Daniel R Matute, Dmitri A Petrov
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/d98125319e5e400194d09f561565f68d
Autor:
Bernard Y Kim, Jeremy R Wang, Danny E Miller, Olga Barmina, Emily Delaney, Ammon Thompson, Aaron A Comeault, David Peede, Emmanuel RR D'Agostino, Julianne Pelaez, Jessica M Aguilar, Diler Haji, Teruyuki Matsunaga, Ellie E Armstrong, Molly Zych, Yoshitaka Ogawa, Marina Stamenković-Radak, Mihailo Jelić, Marija Savić Veselinović, Marija Tanasković, Pavle Erić, Jian-Jun Gao, Takehiro K Katoh, Masanori J Toda, Hideaki Watabe, Masayoshi Watada, Jeremy S Davis, Leonie C Moyle, Giulia Manoli, Enrico Bertolini, Vladimír Košťál, R Scott Hawley, Aya Takahashi, Corbin D Jones, Donald K Price, Noah Whiteman, Artyom Kopp, Daniel R Matute, Dmitri A Petrov
Publikováno v:
eLife, Vol 10 (2021)
Over 100 years of studies in Drosophila melanogaster and related species in the genus Drosophila have facilitated key discoveries in genetics, genomics, and evolution. While high-quality genome assemblies exist for several species in this group, they
Externí odkaz:
https://doaj.org/article/c9a4e43af79a4652bb1b17ca0d8011cd
Publikováno v:
PLoS Genetics, Vol 15, Iss 11, p e1008421 (2019)
Balancer chromosomes are multiply inverted and rearranged chromosomes that are widely used in Drosophila genetics. First described nearly 100 years ago, balancers are used extensively in stock maintenance and complex crosses. Recently, the complete m
Externí odkaz:
https://doaj.org/article/dcb7106dc1e94a628d39542b2ac2068a
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008161 (2019)
During early meiotic prophase, homologous chromosomes are connected along their entire lengths by a proteinaceous tripartite structure known as the synaptonemal complex (SC). Although the components that comprise the SC are predominantly studied in t
Externí odkaz:
https://doaj.org/article/506eb29bc2d94b8ca89224c89a8d63bf
Autor:
Cathleen M Lake, Rachel J Nielsen, Amanda M Bonner, Salam Eche, Sanese White-Brown, Kim S McKim, R Scott Hawley
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007886 (2019)
Meiotic recombination, which is necessary to ensure that homologous chromosomes segregate properly, begins with the induction of meiotic DNA double-strand breaks (DSBs) and ends with the repair of a subset of those breaks into crossovers. Here we inv
Externí odkaz:
https://doaj.org/article/4d881041bc1e449884e0c76903ae472f
Autor:
Brian D Slaughter, R Scott Hawley
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007445 (2018)
Externí odkaz:
https://doaj.org/article/880f6200418c48eaa1eecead173a6509
Autor:
Cathleen M Lake, Rachel J Nielsen, Fengli Guo, Jay R Unruh, Brian D Slaughter, R Scott Hawley
Publikováno v:
eLife, Vol 4 (2015)
Meiotic recombination begins with the induction of programmed double-strand breaks (DSBs). In most organisms only a fraction of DSBs become crossovers. Here we report a novel meiotic gene, vilya, which encodes a protein with homology to Zip3-like pro
Externí odkaz:
https://doaj.org/article/374a93082f654501b793e89cf8a8a2d2
Autor:
Stacie E Hughes, R Scott Hawley
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004650 (2014)
Heterochromatic homology ensures the segregation of achiasmate chromosomes during meiosis I in Drosophila melanogaster females, perhaps as a consequence of the heterochromatic threads that connect achiasmate homologs during prometaphase I. Here, we a
Externí odkaz:
https://doaj.org/article/7579508782cc4eefa407dff94a502d41